Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Richard J. DiPaolo"'
Autor:
Alexander Piening, Emily Ebert, Carter Gottlieb, Niloufar Khojandi, Lindsey M. Kuehm, Stella G. Hoft, Kelly D. Pyles, Kyle S. McCommis, Richard J. DiPaolo, Stephen T. Ferris, Elise Alspach, Ryan M. Teague
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Obesity is a well-established risk factor for human cancer, yet the underlying mechanisms remain elusive. Immune dysfunction is commonly associated with obesity but whether compromised immune surveillance contributes to cancer susceptibility
Externí odkaz:
https://doaj.org/article/cd1f556956cf44109479901a6087aca1
Autor:
Spencer G. Willet, Nattapon Thanintorn, Helen McNeill, Sung-Ho Huh, David M. Ornitz, Won Jae Huh, Stella G. Hoft, Richard J. DiPaolo, Jason C. Mills
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 325-339 (2023)
Background & Aims: Acute and chronic gastric injury induces alterations in differentiation within the corpus of the stomach called pyloric metaplasia. Pyloric metaplasia is characterized by the death of parietal cells and reprogramming of mitotically
Externí odkaz:
https://doaj.org/article/cabec06a0a304c2999d88643e63e8b04
Autor:
Christine N. Noto, Stella G. Hoft, Kevin A. Bockerstett, Nicholas M. Jackson, Eric L. Ford, Luke S. Vest, Richard J. DiPaolo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 623-642 (2022)
Background & Aims: It is well established that chronic inflammation promotes gastric cancer–associated metaplasia, but little is known regarding the mechanisms by which immune cells and cytokines regulate metaplastic cellular changes. The goals of
Externí odkaz:
https://doaj.org/article/31ca8dd185f940d9ac0855d92d7ae0a8
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Single-cell RNA sequencing (scRNAseq) technology is still relatively new in the field of gastric cancer immunology but gaining significant traction. This technology now provides unprecedented insights into the intratumoral and intertumoral heterogene
Externí odkaz:
https://doaj.org/article/c829d707bb294522993d99e8ae7d8be4
Autor:
Kevin A. Bockerstett, Christine P. Petersen, Christine N. Noto, Lindsey M. Kuehm, Chun Fung Wong, Eric L. Ford, Ryan M. Teague, Jason C. Mills, James R. Goldenring, Richard J. DiPaolo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 561-579 (2020)
Background & Aims: The association between chronic inflammation and gastric carcinogenesis is well established, but it is not clear how immune cells and cytokines regulate this process. We investigated the role of interleukin 27 (IL27) in the develop
Externí odkaz:
https://doaj.org/article/a9b943789971460984bc215b4cf4f29f
Autor:
Zhibin Chen, Richard J. DiPaolo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/209abb2f8fd543d88c218cb2631bc17c
Autor:
Elizabeth Geerling, Amanda N. Pinski, Taylor E. Stone, Richard J. DiPaolo, Michael Z. Zulu, Kevin J. Maroney, James D. Brien, Ilhem Messaoudi, Amelia K. Pinto
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103553- (2022)
Summary: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019. Few studies have compared replication dynamics and host responses to SARS-CoV-2 in cell lines from different tissues and species
Externí odkaz:
https://doaj.org/article/6706e14fa6744fd3962e3f683aaae492
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Gastric cancer is a leading cause of mortality worldwide. The risk of developing gastric adenocarcinoma, which comprises >90% of gastric cancers, is multifactorial, but most associated with Helicobacter pylori infection. Autoimmune gastritis is a chr
Externí odkaz:
https://doaj.org/article/3e883cec97e94df4b1e97c505bddfef4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mast cells are an essential part of the immune system and are best known as important modulators of allergic and anaphylactic immune responses. Upon activation, mast cells release a multitude of inflammatory mediators with various effector functions
Externí odkaz:
https://doaj.org/article/c4fa2868a9394740aff8d5b142cf4ba8
Autor:
Ahmad Rajeh, Kyle Wolf, Courtney Schiebout, Nabeel Sait, Tim Kosfeld, Richard J. DiPaolo, Tae-Hyuk Ahn
Publikováno v:
F1000Research, Vol 10 (2021)
The pathogen exposure history of an individual is recorded in their T-cell repertoire and can be accessed through the study of T-cell receptors (TCRs) if the tools to identify them were available. For each T-cell, the TCR loci undergoes genetic rearr
Externí odkaz:
https://doaj.org/article/3f3fbdbe14be428d8e24c245f4435416