Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Richard J. Byers"'
Autor:
Tim D.D. Somerville, Fabrizio Simeoni, John A. Chadwick, Emma L. Williams, Gary J. Spencer, Katalin Boros, Christopher Wirth, Eleni Tholouli, Richard J. Byers, Tim C.P. Somervaille
Publikováno v:
Cell Reports, Vol 22, Iss 3, Pp 638-652 (2018)
The Iroquois homeodomain transcription factor gene IRX3 is expressed in the developing nervous system, limb buds, and heart, and transcript levels specify obesity risk in humans. We now report a functional role for IRX3 in human acute leukemia. Altho
Externí odkaz:
https://doaj.org/article/4afa71a0ca914ca1a316ea4f6f7850b2
Autor:
Richard J Byers, Anita J Byers, Chibamba Mumba, Angela Mutuku, Jennifer Singer-Rupp, Michael Wilson, Kenneth Fleming, Shahin Sayed
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundResource barriers to the provision of accessible training in cancer diagnosis in lower- and middle-income countries (LMICs) limit the potential of African health systems. Long-term provision via teaching visits from senior pathologists and
Externí odkaz:
https://doaj.org/article/401777e4d39e4cfaa46d6a9789dd5c22
Autor:
Kim Linton, Richard J. Byers, Martin Fergie, Anna-Maria Tsakiroglou, Elaine F. Harkness, Adeline Rosenberg, Susan M. Astley, Matthew Sperrin, Manas Dave, Catharine M L West
Publikováno v:
Cancer Immunology, Immunotherapy
Tsakiroglou, A-M, Astley, S, Dave, M, Fergie, M, Harkness, E, Rosenberg, A, Sperrin, M, West, C, Byers, R & Linton, K 2021, ' Immune infiltrate diversity confers a good prognosis in follicular lymphoma ', Cancer immunology, immunotherapy : CII . https://doi.org/10.1007/s00262-021-02945-0
Tsakiroglou, A-M, Astley, S, Dave, M, Fergie, M, Harkness, E, Rosenberg, A, Sperrin, M, West, C, Byers, R & Linton, K 2021, ' Immune infiltrate diversity confers a good prognosis in follicular lymphoma ', Cancer immunology, immunotherapy : CII . https://doi.org/10.1007/s00262-021-02945-0
Background Follicular lymphoma (FL) prognosis is influenced by the composition of the tumour microenvironment. We tested an automated approach to quantitatively assess the phenotypic and spatial immune infiltrate diversity as a prognostic biomarker f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8464b3152604ba52170d53791e042198
http://europepmc.org/articles/PMC8571143
http://europepmc.org/articles/PMC8571143
Autor:
Martin Fergie, Kenneth K Oguejiofor, Kim Linton, Anna Maria Tsakiroglou, Peter L. Stern, Catharine M L West, Richard J. Byers, David J Thomson, Susan M. Astley
Publikováno v:
Tsakiroglou, A M, Fergie, M, Oguejiofor, K, Linton, K, Thomson, D, Stern, P L, Astley, S, Byers, R & West, C M L 2019, ' Spatial proximity between T and PD-L1 expressing cells as a prognostic biomarker for oropharyngeal squamous cell carcinoma ', British Journal of Cancer, vol. 122, pp. 539–544 . https://doi.org/10.1038/s41416-019-0634-z
British Journal of Cancer
British Journal of Cancer
Background Fulfilling the promise of cancer immunotherapy requires novel predictive biomarkers to characterise the host immune microenvironment. Deciphering the complexity of immune cell interactions requires an automated multiplex approach to histol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b278a7ed9a9839a65778323d9003bb50
https://doi.org/10.1038/s41416-019-0634-z
https://doi.org/10.1038/s41416-019-0634-z
Autor:
Richard J. Byers, Newton A C S Wong, Rachel Butler, Manuel Salto-Tellez, Mohammad Ilyas, Philippe Taniere, Fernanda Amary, Harry R Haynes, David Gonzalez
Publikováno v:
Wong, N A C S, Amary, F, Butler, R, Byers, R, Gonzalez, D, Haynes, H R, Ilyas, M, Salto-Tellez, M & Taniere, P 2018, ' HER2 testing of gastro-oesophageal adenocarcinoma : a commentary and guidance document from the Association of Clinical Pathologists Molecular Pathology and Diagnostics Committee ', Journal of Clinical Pathology, vol. 71, no. 5, pp. 388-394 . https://doi.org/10.1136/jclinpath-2017-204943
The use of biologics targeted to the human epidermal growth factor receptor 2 (HER2) protein is the latest addition to the armamentarium used to fight advanced gastric or gastro-oesophageal junction adenocarcinoma. The decision to treat with the biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c889757c4c2a29db116320e965b1f93c
https://doi.org/10.1136/jclinpath-2017-204943
https://doi.org/10.1136/jclinpath-2017-204943
Autor:
Timothy M Illidge, Cathy Burton, Sally F. Barrington, John Radford, Kim Linton, Rachel Oakley, Nicholas Counsell, Joanna Williams, Joanna M Oladipo, Janet Taylor, Richard J. Byers
Publikováno v:
Blood. 136:18-19
Introduction: Interim PET identifies patients with early stage classical HL (cHL) suitable for risk-adapted treatment escalation or de-escalation, but relapse-free survival remains inferior for patients with a negative interim PET who omit radiothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02452e928990e83aa1e9f84a614dd2f
https://doi.org/10.1182/blood-2020-136318
https://doi.org/10.1182/blood-2020-136318
Autor:
Abigail E. Derbyshire, Richard J. Byers, Michelle L. MacKintosh, Basil J. Ammori, Steven Bagley, Martin Fergie, Anie Naqvi, James Bolton, Anna Maria Tsakiroglou, Akheel A. Syed, Emma J Crosbie, Phillip W. Pemberton, Garry Ashton, Rhona J McVey, Thomas D. J. Walker
Publikováno v:
The Journal of Pathology. 249
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337c9c941b1efd427e38cb590d03d412
https://doi.org/10.1002/path.5345
https://doi.org/10.1002/path.5345
Publikováno v:
Journal of Clinical Pathology. 70:571-574
AimsPrimary cilia play an important role in the regulation of cell signalling pathways and are thought to have a role in cancer but have seldom been studied in human cancer samples.MethodsPrimary cilia were visualised by dual immunofluorescence for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b3bcd8518b944dc1ec6b62a69de00c
https://doi.org/10.1136/jclinpath-2016-204103
https://doi.org/10.1136/jclinpath-2016-204103
Publikováno v:
Journal of Pathology Informatics, Vol 4, Iss 2, Pp 4-4 (2013)
Background: Multispectral microscopy and multiple staining can be used to identify cells with distinct immunohistochemical (IHC) characteristics. We present here a method called hypothesized interaction distribution (HID) analysis for characterizing
Externí odkaz:
https://doaj.org/article/1d01eb61ba644f0a86fcfc0dc72fbeb0
Autor:
Martin Fergie, Sophie Fitzpatrick, Kang Zeng, Anna Maria Tsakiroglou, Lilli Nelson, Catharine M L West, Richard J. Byers, Susan M. Astley, Kim Linton, Garry Ashton
Publikováno v:
Medical Imaging: Digital Pathology
Tsakiroglou, A M, Fergie, M, West, C, Linton, K, Astley, S, Byers, R, Fitzpatrick, S, Zeng, K, Ashton, G & Nelson, L 2018, ' Quantifying cell-type interactions and their spatial patterns as prognostic biomarkers in follicular lymphoma ', Proceedings Of The Society Of Photo-Optical Instrumentation Engineers (Spie), . https://doi.org/10.1117/12.2293572
Tsakiroglou, A M, Fergie, M, West, C, Linton, K, Astley, S, Byers, R, Fitzpatrick, S, Zeng, K, Ashton, G & Nelson, L 2018, ' Quantifying cell-type interactions and their spatial patterns as prognostic biomarkers in follicular lymphoma ', Proceedings Of The Society Of Photo-Optical Instrumentation Engineers (Spie), . https://doi.org/10.1117/12.2293572
Background: Observing the spatial pattern of tumour infiltrating lymphocytes in follicular lymphoma can lead to the development of promising novel biomarkers for survival prognosis. We have developed the “Hypothesised Interactions Distribution” (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613236e07233e6aa4a0a759106322c0c
https://doi.org/10.1117/12.2293572
https://doi.org/10.1117/12.2293572