Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Richard J. Bryant"'
Autor:
Ioana R. Marian, Alexander Ooms, Jane Holmes, Matthew J. Parkes, Alastair D. Lamb, Richard J. Bryant
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background The TRANSLATE (TRANSrectal biopsy versus Local Anaesthetic Transperineal biopsy Evaluation) trial assesses the clinical and cost-effectiveness of two biopsy procedures in terms of detection of clinically significant prostate cance
Externí odkaz:
https://doaj.org/article/06521101632f458bae35061011c1d43c
Autor:
Benjamin H. L. Harris, Matteo Di Giovannantonio, Ping Zhang, David A. Harris, Simon R. Lord, Naomi E. Allen, Tim S. Maughan, Richard J. Bryant, Adrian L. Harris, Gareth L. Bond, Francesca M. Buffa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cancer risk is associated with the widely debated measure body mass index (BMI). Fat mass and fat-free mass measurements from bioelectrical impedance may further clarify this association. The UK Biobank is a rare resource in which bioelectri
Externí odkaz:
https://doaj.org/article/2f3050f839a7488a9330c4b7083a5352
Autor:
Srinivasa Rao, Clare Verrill, Lucia Cerundolo, Nasullah Khalid Alham, Zeynep Kaya, Miriam O’Hanlon, Alicia Hayes, Adam Lambert, Martha James, Iain D. C. Tullis, Jane Niederer, Shelagh Lovell, Altan Omer, Francisco Lopez, Tom Leslie, Francesca Buffa, Richard J. Bryant, Alastair D. Lamb, Boris Vojnovic, David C. Wedge, Ian G. Mills, Dan J. Woodcock, Ian Tomlinson, Freddie C. Hamdy
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Extension of prostate cancer beyond the primary site by local invasion or nodal metastasis is associated with poor prognosis. Despite significant research on tumour evolution in prostate cancer metastasis, the emergence and evolut
Externí odkaz:
https://doaj.org/article/fea0ecc091594c4e9bf661d9a47540cf
Autor:
Sandy Figiel, Wencheng Yin, Dimitrios Doultsinos, Andrew Erickson, Ninu Poulose, Reema Singh, Anette Magnussen, Thineskrishna Anbarasan, Renuka Teague, Mengxiao He, Joakim Lundeberg, Massimo Loda, Clare Verrill, Richard Colling, Pelvender S. Gill, Richard J. Bryant, Freddie C. Hamdy, Dan J. Woodcock, Ian G. Mills, Olivier Cussenot, Alastair D. Lamb
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-5 (2023)
Abstract Genetic signatures have added a molecular dimension to prognostics and therapeutic decision-making. However, tumour heterogeneity in prostate cancer and current sampling methods could confound accurate assessment. Based on previously publish
Externí odkaz:
https://doaj.org/article/586aa75e487c4ec0a28a445500a1ab30
Autor:
Olivier Cussenot, Ruth Macpherson, Tom Leslie, Luca Lunelli, Giancarlo Marra, Marc Laniado, Freddie C. Hamdy, Richard J. Bryant
Publikováno v:
Anatomia, Vol 2, Iss 3, Pp 232-242 (2023)
Irreversible electroporation (IRE) is a recent and minimally invasive method of partial prostate ablation. However, knowledge of the essential landmarks of prostate anatomy is crucial to achieving safe and effective partial ablation by IRE. High-qual
Externí odkaz:
https://doaj.org/article/f3a1b396b8ce47dca093b7c97e407d44
Autor:
Srinivasa R. Rao, Andrew Protheroe, Lucia Cerundolo, David Maldonado-Perez, Lisa Browning, Alastair D. Lamb, Richard J. Bryant, Ian G. Mills, Dan J. Woodcock, Freddie C. Hamdy, Ian P. M. Tomlinson, Clare Verrill
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12722 (2023)
Prostate cancer is typically of acinar adenocarcinoma type but can occasionally present as neuroendocrine and/or ductal type carcinoma. These are associated with clinically aggressive disease, and the former often arises on a background of androgen d
Externí odkaz:
https://doaj.org/article/3dc858a542854e47aba148547ce1d7ed
Autor:
Veena Somasundaram, Lisa A. Ridnour, Robert YS. Cheng, Abigail J. Walke, Noemi Kedei, Dibyangana D. Bhattacharyya, Adelaide L. Wink, Elijah F. Edmondson, Donna Butcher, Andrew C. Warner, Tiffany H. Dorsey, David A. Scheiblin, William Heinz, Richard J. Bryant, Robert J. Kinders, Stanley Lipkowitz, Stephen TC. Wong, Milind Pore, Stephen M. Hewitt, Daniel W. McVicar, Stephen K. Anderson, Jenny Chang, Sharon A. Glynn, Stefan Ambs, Stephen J. Lockett, David A. Wink
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102529- (2022)
Antitumor immune polarization is a key predictor of clinical outcomes to cancer therapy. An emerging concept influencing clinical outcome involves the spatial location of CD8+ T cells, within the tumor. Our earlier work demonstrated immunosuppressive
Externí odkaz:
https://doaj.org/article/861cead31d3f4ebb8be3e8669adfe0cf
Autor:
Kai Rakovic, Richard Colling, Lisa Browning, Monica Dolton, Margaret R. Horton, Andrew Protheroe, Alastair D. Lamb, Richard J. Bryant, Richard Scheffer, James Crofts, Ewart Stanislaus, Clare Verrill
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1225 (2022)
There has been particular interest in the deployment of digital pathology (DP) and artificial intelligence (AI) in the diagnosis of prostate cancer, but little is known about the views of the public on their use. Prostate Cancer UK supporters were in
Externí odkaz:
https://doaj.org/article/a0d50451df7243d296850f599a640310
Autor:
Annelies Gonnissen, Sofie Isebaert, Christiaan Perneel, Chad M. McKee, Clare Verrill, Richard J. Bryant, Filip Van Utterbeeck, Evelyne Lerut, Karin Haustermans, Ruth J. Muschel
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-7 (2017)
Abstract Background Prostate cancer (PCa) is a heterogeneous disease with a variable natural history, genetics, and treatment outcome. The Hedgehog (Hh) signaling pathway is increasingly recognized as being potentially important for the development a
Externí odkaz:
https://doaj.org/article/73aa47090a9744e39ca68a40e77237b4
Autor:
Valentine M. Macaulay, Stephen Taylor, Thomas Bogenrieder, Michael P. Sanderson, Ulrike Weyer-Czernilofsky, Freddie C. Hamdy, Rajeev Kumar, Adam G. Lambert, Kathryn Hutchinson, Cheng Han, Richard J. Bryant, Clare Verrill, Jack Mills, Eliot Osher, Guillaume Rieunier, Xiaoning Wu, Nicki Gray, Tamara Aleksic
Supplementary file containing: Supplementary methods Table S1: Primers, probes and siRNAs used in this study. Table S2: Demographics of men treated by radical prostatectomy for prostate cancer. Table S3: IGF-1R scores and clinical parameters in men u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573218d9a30e08fded720f68f497737d
https://doi.org/10.1158/0008-5472.22420502
https://doi.org/10.1158/0008-5472.22420502