Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Richard J. Atherley"'
Autor:
JongBun Kim, Richard J. Atherley, Joseph F. Antognini, David F. Werner, Earl Carstens, Gregg E. Homanics
Publikováno v:
Neuroscience Letters. 420:209-212
Anesthetics produce immobility and depress spinal nociceptive processing, but the exact sites and mechanisms of anesthetic action are unknown. The gamma-aminobutyric acid type-A (GABA A ) receptor is thought to be important to anesthetic action. We s
Autor:
Earl Carstens, Richard J. Atherley, Michael J. Laster, Joseph F. Antognini, Robert C. Dutton, Edmond I. Eger
Publikováno v:
Anesthesia & Analgesia. 104:829-835
BACKGROUND: Because of the logistical obstacles to measurement under hyperbaric conditions, the effect of nitrous oxide (N 2 O) alone on spinal neuronal responses has not been tested. We hypothesized that, like other inhaled anesthetics, N 2 O would
Publikováno v:
Acta Anaesthesiologica Scandinavica. 50:993-998
Background: Halothane and propofol depress the central nervous system, and this is partly manifested by a decrease in electroencephalographic (EEG) activity. Little work has been performed to determine the differences between these anesthetics with r
Publikováno v:
British Journal of Anaesthesia. 96:216-221
Background Although N2O has been widely used as an anaesthetic adjuvant its effect on electroencephalographic (EEG) activity is poorly understood because it is usually studied in the presence of additional anaesthetics, including inhaled anaesthetics
Publikováno v:
Biomedical Chromatography. 18:714-718
We have developed a technique to determine the concentration of volatile anesthetics (halothane, isoflurane and sevoflurane) in blood that is a modification of a method used for volatile anesthetics in Krebs solution. Methylene chloride was the inter
Publikováno v:
Anesthesia & Analgesia. :999-1003
UNLABELLED Anesthetics act in the spinal cord to ablate both movement and the ascending transmission of nociceptive information. We investigated whether a spinal cord action of isoflurane affected cortical activity as determined by the electroencepha
Immobility is an end-point that is produced by all general anesthetics and is predominantly mediated by the spinal cord.1;2 Sonner et al showed that the mechanism by which 2 commonly used anesthetics, propofol and isoflurane, causes immobility is dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8de10314ac8fc4584bb5a01c55aa97
https://europepmc.org/articles/PMC3148181/
https://europepmc.org/articles/PMC3148181/
Autor:
JongBun Kim, Aubrey P Yao, Sean Shargh, Steven L. Jinks, Richard J. Atherley, Earl Carstens, Alana Sulger, Joseph F. Antognini
Publikováno v:
Anesthesia and analgesia. 106(6)
BACKGROUND: Gamma-aminobutyric acid type A receptor potentiation and/or N-methyl-Daspartate (NMDA) receptor inhibition might explain the anesthetic properties of fluorinated aromatic compounds. We hypothesized that depression of dorsal horn neuronal
Autor:
JongBun Kim, Joseph F. Antognini, Aubrey P Yao, Earl Carstens, Steven L. Jinks, Richard J. Atherley
Publikováno v:
Anesthesia and analgesia. 105(4)
Volatile anesthetics act primarily in the spinal cord to produce immobility but their exact site of action is unclear. Between 0.8 and 1.2 minimum alveolar anesthetic concentration (MAC), isoflurane does not depress neurons in the dorsal horn, sugges
Autor:
Linda S Barter, Katarzyna Jankowska, Emigdio Bravo, Richard J. Atherley, Edmond I. Eger, M. J. Laster, Douglas E. Raines, Joseph F. Antognini, Ken Solt
Publikováno v:
Anesthesia and analgesia. 104(4)
BACKGROUND Previous work demonstrated that isoflurane and halothane act on the spinal cord rather than on the brain to produce immobility in the face of noxious stimulation. These anesthetics share many effects on specific receptors, and thus do not