Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Richard J Whitby"'
Autor:
Jennifer L Mamrosh, Jae Man Lee, Martin Wagner, Peter J Stambrook, Richard J Whitby, Richard N Sifers, San-Pin Wu, Ming-Jer Tsai, Francesco J DeMayo, David D Moore
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/7cb0c66bbfc04c7ea1650a865d96bc55
Autor:
Vijyesh K. Vyas, George R. Bacanu, Murari Soundararajan, Elizabeth S. Marsden, Tanzeeha Jafari, Anna Shugai, Mark E. Light, Urmas Nagel, Toomas Rõõm, Malcolm H. Levitt, Richard J. Whitby
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The cavity inside fullerene C60 provides a highly symmetric and inert environment for housing atoms and small molecules. Here we report the encapsulation of formaldehyde inside C60 by molecular surgery, yielding the supermolecular complex CH
Externí odkaz:
https://doaj.org/article/6a5940fd03964202935337481b8b97fb
Autor:
Jennifer L Mamrosh, Jae Man Lee, Martin Wagner, Peter J Stambrook, Richard J Whitby, Richard N Sifers, San-Pin Wu, Ming-Jer Tsai, Francesco J DeMayo, David D Moore
Publikováno v:
eLife, Vol 3 (2014)
Chronic endoplasmic reticulum (ER) stress results in toxicity that contributes to multiple human disorders. We report a stress resolution pathway initiated by the nuclear receptor LRH-1 that is independent of known unfolded protein response (UPR) pat
Externí odkaz:
https://doaj.org/article/1cc3ba7a8d1b4fd08d92d37e45f4bf72
Autor:
Sally Bloodworth, Richard J. Whitby
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-14 (2022)
‘Molecular surgery’ is a useful method through which to create endohedral fullerenes that aren’t accessible by conventional physical methods of trapping small atoms and molecules. Here, the authors review the organic chemistry behind molecular
Externí odkaz:
https://doaj.org/article/a8b4b29053014925aee128e72425190d
Autor:
Samuel P. Jarvis, Hongqian Sang, Filipe Junqueira, Oliver Gordon, Jo E. A. Hodgkinson, Alex Saywell, Philipp Rahe, Salvatore Mamone, Simon Taylor, Adam Sweetman, Jeremy Leaf, David A. Duncan, Tien-Lin Lee, Pardeep K. Thakur, Gabriella Hoffman, Richard J. Whitby, Malcolm H. Levitt, Georg Held, Lev Kantorovich, Philip Moriarty, Robert G. Jones
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-7 (2021)
The chemical nature of molecules encapsulated within fullerenes remain debated, with reports proposing a Faraday cage effect. Here, the authors show that H2O and HF molecules encapsulated inside a C60 cage experience a substantial intra-cage electros
Externí odkaz:
https://doaj.org/article/07e30074e71842c896f80b0abfb21066
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Chirality is an important consideration in drug development: it can influence recognition of the intended target, pharmacokinetics, and off-target effects. Here, we investigate how chirality affects the activity and mechanism of action of RJ
Externí odkaz:
https://doaj.org/article/bde5e80a95114cbbb7800f850e004f61
Publikováno v:
The Journal of Organic Chemistry. 88:5341-5347
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709b90c72ec0e3ea08691dfd119d0855
https://doi.org/10.1021/acs.joc.2c02861
https://doi.org/10.1021/acs.joc.2c02861
Autor:
Dawid Drelinkiewicz, Richard J. Whitby
Publikováno v:
RSC Advances. 12:28910-28915
A robust and versatile protocol for synthesis of 1-monosubstituted and 1,4-disubstituted 1H-1,2,3-triazoles was established under continuous flow conditions using copper-on-charcoal as a heterogeneous catalyst. This methodology allowed for the synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b04acb4613d9980ab28717cf4cc6fc
https://doi.org/10.1039/d2ra04727f
https://doi.org/10.1039/d2ra04727f
Autor:
Johanna Rademacher, Elliott S. Reedy, Fabrizia Negri, Shamim Alom, Richard J. Whitby, Malcolm H. Levitt, Ewen K. Campbell
Publikováno v:
Molecular Physics.
Gas-phase electronic spectra of H2O@C+60 and D2O@C+60 are presented. These data were obtained by one-photon dissociation of weakly bound helium complexes synthesised in a 3 K ion trap. Mea- surements were recorded in the vicinity of the 2 Ag ,2 Bg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a5a28efc1c0c127456ace021e20e6d
https://doi.org/10.1080/00268976.2023.2173507
https://doi.org/10.1080/00268976.2023.2173507
Publikováno v:
Crystal Growth & Design. 22:559-569
In this study, we have combined structural comparisons and the rugosity model to investigate experimental and predicted crystal structures from previous results of a crystal structure prediction study on a group of three rigid, planar small molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5bf1be1fa8497019cff0fbc5b740ed5
https://doi.org/10.1021/acs.cgd.1c01132
https://doi.org/10.1021/acs.cgd.1c01132