Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Richard J Prankerd"'
Autor:
Tri-Hung Nguyen, Peter Lambert, Rajpreet Singh Minhas, Claire McEvoy, Kim Deadman, Philip Wright, Richard J Prankerd, Seloi Mogatle, Michelle P McIntosh
Publikováno v:
BMJ Open, Vol 9, Iss 7 (2019)
Introduction Oxytocin, administered via injection, is recommended by WHO for the prevention and treatment of postpartum haemorrhage. However, the susceptibility of oxytocin injection to thermal degradation has led WHO and UNICEF to recommend cold-cha
Externí odkaz:
https://doaj.org/article/9e25142c85874fa58ba7b37a1eaa3465
Autor:
Richard J Prankerd, Tri-Hung Nguyen, Jibriil P Ibrahim, Robert J Bischof, Gemma C Nassta, Livesey D Olerile, Adrian S Russell, Felix Meiser, Helena C Parkington, Harold A Coleman, David A V Morton, Michelle P McIntosh
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82965 (2013)
Oxytocin is recommended by the World Health Organisation as the most effective uterotonic for the prevention and treatment of postpartum haemorrhage. The requirement for parenteral administration by trained healthcare providers and the need for the d
Externí odkaz:
https://doaj.org/article/78913c02b58f49af9aacc7792db5e3bc
Publikováno v:
The Australian Journal of Hospital Pharmacy. 29:149-154
The potential for gene therapy of some genetically based human diseases is given, then some fundamental background on the structure and mechanism of action of genes. Some important approaches to the delivery of genetic material to cells and some of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26e63f62216bf608ce5c0b392acd2518
https://doi.org/10.1002/jppr1999293149
https://doi.org/10.1002/jppr1999293149
Publikováno v:
The Australian Journal of Hospital Pharmacy. 29:20-27
This review describes the problems of using peptides and proteins as therapeutic agents, approaches used in overcoming these problems and alternatives to the oral route of administration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a1240ecd37687b55dcbe191f190a70
https://doi.org/10.1002/jppr199929120
https://doi.org/10.1002/jppr199929120
Publikováno v:
The Australian Journal of Hospital Pharmacy. 28:417-425
Site-specific delivery of small molecule drugs is briefly reviewed. The area is divided into molecular design and formulation approaches to modifying the biodistribution of a drug molecule, such that delivery to one part of the body is favoured over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::594fe7a4b750fe717aaef077c9dd9b70
https://doi.org/10.1002/jppr1998286417
https://doi.org/10.1002/jppr1998286417
Autor:
Richard J Prankerd, Heather Ah Benson
Publikováno v:
The Australian Journal of Hospital Pharmacy. 28:318-324
This article reviews the current status and possible future applications of drug delivery via the mucosal membranes of the eye, vagina and rectum, as well as a little of its history. The anatomy of each administration site is briefly discussed with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37402ed73689850470074fe7a1d45569
https://doi.org/10.1002/jppr1998285318
https://doi.org/10.1002/jppr1998285318
Autor:
Richard J Prankerd, Heather AE Benson
Publikováno v:
The Australian Journal of Hospital Pharmacy. 28:165-173
This article reviews the application of bioreversible chemical modification to overcome drug delivery of drug utilisation problems. This involves the use of prodrugs, 'soft' drugs and chemical delivery systems. Mechanisms are outlined for some specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794ac70c932e92ed09f21280e65dd7e1
https://doi.org/10.1002/jppr1998283165
https://doi.org/10.1002/jppr1998283165
Publikováno v:
The Australian Journal of Hospital Pharmacy. 28:99-104
This article reviews the origins, current status and possible future directions for drug delivery using modified-release parenteral products, including implants. The physicochemical bases for modified drug release profiles, their advantages and disad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0869accef6cfea6904d41b16bbd4716
https://doi.org/10.1002/jppr199828299
https://doi.org/10.1002/jppr199828299
Publikováno v:
International Journal of Pharmaceutics. 163:177-190
The aim of this work is to develop 3-acyl prodrugs of the potent analgesic morphine-6-sulfate (M6S). These are expected to have higher potency and/or exhibit longer duration of analgesic action than the parent compound. M6S and the prodrugs were synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daca14213a5f4c052ac510ba267941db
https://doi.org/10.1016/s0378-5173(97)00381-5
https://doi.org/10.1016/s0378-5173(97)00381-5
Publikováno v:
International Journal of Pharmaceutics. 163:191-201
This investigation was designed to examine the antinociceptive activity in rats of 3-O-acyl prodrugs of M6S relative to the parent drug, after intravenous and intramuscular injection, using the tail flick latency test of antinociception. M6S, 3-acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::390a041cdce27e0617e8e3960c70b0b7
https://doi.org/10.1016/s0378-5173(97)00380-3
https://doi.org/10.1016/s0378-5173(97)00380-3