Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Richard J Levy"'
Autor:
Dhwajbahadur K Rawat, Peter Hecker, Makino Watanabe, Sukrutha Chettimada, Richard J Levy, Takao Okada, John G Edwards, Sachin A Gupte
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45365 (2012)
We recently demonstrated that a 17-ketosteroid, epiandrosterone, attenuates L-type Ca(2+) currents (I(Ca-L)) in cardiac myocytes and inhibits myocardial contractility. Because 17-ketosteroids are known to inhibit glucose-6-phosphate dehydrogenase (G6
Externí odkaz:
https://doaj.org/article/feb043ae5a404445ba4069be56cb7215
Autor:
Ying Cheng, Adia Thomas, Feras Mardini, Shannon L Bianchi, Junxia X Tang, Jun Peng, Huafeng Wei, Maryellen F Eckenhoff, Roderic G Eckenhoff, Richard J Levy
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32029 (2012)
Carbon monoxide (CO) exposure at high concentrations results in overt neurotoxicity. Exposure to low CO concentrations occurs commonly yet is usually sub-clinical. Infants are uniquely vulnerable to a variety of toxins, however, the effects of postna
Externí odkaz:
https://doaj.org/article/80c40d9e0d2c46cbb9a321fdd698cab1
Publikováno v:
Journal of Neurosurgical Anesthesiology. 35:97-103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0975153ab3353234f4c56845e1fdf561
https://doi.org/10.1097/ana.0000000000000886
https://doi.org/10.1097/ana.0000000000000886
Publikováno v:
MethodsX, Vol 7, Iss , Pp 101058- (2020)
The Langendorff-perfused model is a powerful tool to study biological responses in the isolated heart in the absence of confounders. The model has been adapted recently to enable study of the isolated mouse heart and the effects of genetic manipulati
Externí odkaz:
https://doaj.org/article/b879f889590941b7b467b72e131dc611
Publikováno v:
Mitochondrion. 65:1-10
Brown adipose tissue (BAT) mitochondria generate heat via uncoupled respiration due to excessive proton leak through uncoupling proteins (UCPs). We previously found hyperthermia in a newborn mouse model of fragile X syndrome and excessive leak in Fmr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff46098a5747a91fce95440208688feb
https://doi.org/10.1016/j.mito.2022.04.003
https://doi.org/10.1016/j.mito.2022.04.003
Autor:
Richard J. Levy
Publikováno v:
Carbon Monoxide in Drug Discovery. :286-301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088511e5048ad486e9f3db30447b40ed
https://doi.org/10.1002/9781119783435.ch16
https://doi.org/10.1002/9781119783435.ch16
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex
Autor:
Nelli Mnatsakanyan, Han-A Park, Jing Wu, Xiang He, Marc C. Llaguno, Maria Latta, Paige Miranda, Besnik Murtishi, Morven Graham, Joachim Weber, Richard J. Levy, Evgeny V. Pavlov, Elizabeth A. Jonas
Publikováno v:
Cell Death & Differentiation. 29:1874-1887
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4741c186f970772952c9a055389a99
https://doi.org/10.1038/s41418-022-00972-7
https://doi.org/10.1038/s41418-022-00972-7
Publikováno v:
Pediatric Research. 92:1341-1349
Background Propofol infusion syndrome (PRIS) is a potentially lethal consequence of long-term propofol administration. Children are vulnerable and cardiac involvement is often prominent and associated with mortality. We aimed to determine the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88497a3e8621053ddecc506d69ef0e8
https://doi.org/10.1038/s41390-022-01985-1
https://doi.org/10.1038/s41390-022-01985-1
Autor:
Jerri C. Price, Jennifer J. Lee, Caleb Ing, Guohua Li, Jacquelin Narula, Mary K. Clark, Steven Stylianos, Robert A. Whittington, Richard J. Levy, Lena S. Sun
Publikováno v:
Journal of Neurosurgical Anesthesiology. 34:132-135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcfe0a9ec8c2ce4dd4f3adfa7d0c22b5
https://doi.org/10.1097/ana.0000000000000805
https://doi.org/10.1097/ana.0000000000000805
Publikováno v:
Physiological reports. 10(15)
Infants and children are vulnerable to developing propofol infusion syndrome (PRIS) and young age is a risk factor. Cardiac involvement is often prominent and associated with death. However, the mechanisms of pediatric PRIS are poorly understood beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e9e3d8bc891efb117f94a2f82397ec
https://pubmed.ncbi.nlm.nih.gov/35923108
https://pubmed.ncbi.nlm.nih.gov/35923108