Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Richard J Grainger"'
Publikováno v:
Frontiers in Marine Science, Vol 7 (2021)
Ocean warming (OW) and acidification (OA) affects nearly all aspects of marine organism physiology and it is important to consider both stressors when predicting responses to climate change. We investigated the effects of long-term exposure to OW and
Externí odkaz:
https://doaj.org/article/acae7a209a9c4e64aa1c02aba9796780
Autor:
Tatsiana Auchynnikava, Jean D. Beggs, Parastoo Ehsani, Richard J. Grainger, Kum-Loong Boon, Chris F. Inglehearn, J. David Barrass
Publikováno v:
Nature Structural & Molecular Biology. 14:1077-1083
Prp8 protein (Prp8p) is a highly conserved pre-mRNA splicing factor and a component of spliceosomal U5 small nuclear ribonucleoproteins (snRNPs). Although it is ubiquitously expressed, mutations in the C terminus of human Prp8p cause the retina-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ea5c62570c8988dec04a7ea196e91a
https://doi.org/10.1038/nsmb1303
https://doi.org/10.1038/nsmb1303
Publikováno v:
Nucleic Acids Research
Pre-mRNA splicing involves two transesterification steps catalyzed by the spliceosome. How RNA substrates are positioned in each step and the molecular rearrangements involved, remain obscure. Here, we show that mutations in PRP16, PRP8, SNU114 and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e06988a3de8e2784963f06b0368b1321
https://pubmed.ncbi.nlm.nih.gov/25740649
https://pubmed.ncbi.nlm.nih.gov/25740649
Autor:
Richard J. Grainger, Jean D. Beggs
Publikováno v:
RNA. 11:533-557
Pre-messenger RNA (pre-mRNA) splicing is a central step in gene expression. Lying between transcription and protein synthesis, pre-mRNA splicing removes sequences (introns) that would otherwise disrupt the coding potential of intron-containing transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213f041d2c65636cb45dbc9e4d6b5642
https://doi.org/10.1261/rna.2220705
https://doi.org/10.1261/rna.2220705
Autor:
Richard J. Grainger
Publikováno v:
Journal of Teaching in International Business. 12:87-101
Educational exports are worth three billion dollars per annum to the Australian economy and are Australia's fifth largest export. Within this overall context, Australian commerce faculties have benefited disproportionately because of the popularity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c81c8ed638202e436d0bbe0321b07613
https://doi.org/10.1300/j066v12n03_05
https://doi.org/10.1300/j066v12n03_05
Publikováno v:
Biochemistry. 39:6317-6324
Fluorescence resonance energy transfer provides valuable long-range distance information about macromolecules in solution. Fluorescein and Cy3 are an important donor-acceptor pair of fluorophores; the characteristic Förster length for this pair on D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede8f5828e910e4ff9b65471c5ceab0b
https://doi.org/10.1021/bi992944a
https://doi.org/10.1021/bi992944a
Publikováno v:
Journal of Molecular Biology. 288:585-594
We have studied the global structure of the U1A 3' untranslated region (UTR) element using fluorescence resonance energy transfer. Comparison of a single UTR-box with a series of oligoadenine bulges indicates that the UTR-box introduces a significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b24865fff208639a841ebb6345ef043
https://doi.org/10.1006/jmbi.1999.2717
https://doi.org/10.1006/jmbi.1999.2717
Publikováno v:
Grainger, R J, Barrass, J D, Jacquier, A, Rain, J-C & Beggs, J D 2009, ' Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome ', RNA, vol. 15, no. 12, pp. 2161-2173 . https://doi.org/10.1261/rna.1908309
In Saccharomyces cerevisiae, Cwc21p is a protein of unknown function that is associated with the NineTeen Complex (NTC), a group of proteins involved in activating the spliceosome to promote the pre-mRNA splicing reaction. Here, we show that Cwc21p b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5a80bff089087ed8a4b05cb1b5c42d
https://www.pure.ed.ac.uk/ws/files/7536092/RNA_2009_Beggs.pdf
https://www.pure.ed.ac.uk/ws/files/7536092/RNA_2009_Beggs.pdf
Autor:
Lenka, Ivings, Katherine V, Towns, M A, Matin, Charles, Taylor, Frederique, Ponchel, Richard J, Grainger, Rajkumar S, Ramesar, David A, Mackey, Chris F, Inglehearn
Publikováno v:
Molecular Vision
Purpose Retinitis pigmentosa (RP) is caused by mutations in a variety of genes, most of which have known functions in the retina. However, one of the most perplexing findings of recent retinal genetics research was the discovery of mutations causing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7404f5dc25569c3c276234e2e5681c8e
https://pubmed.ncbi.nlm.nih.gov/19096719
https://pubmed.ncbi.nlm.nih.gov/19096719