Výsledky vyhledávání - "Richard J Deckelbaum"

Akademický článek

DHA but Not EPA Emulsions Preserve Neurological and Mitochondrial Function after Brain Hypoxia-Ischemia in Neonatal Mice.

Autor: Korapat Mayurasakorn, Zoya V Niatsetskaya, Sergey A Sosunov, Jill J Williams, Hylde Zirpoli, Iliyan Vlasakov, Richard J Deckelbaum, Vadim S Ten

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160870 (2016)

Treatment with triglyceride emulsions of docosahexaenoic acid (tri-DHA) protected neonatal mice against hypoxia-ischemia (HI) brain injury. The mechanism of this neuroprotection remains unclear. We hypothesized that administration of tri-DHA enriches

Externí odkaz: https://doaj.org/article/25908a8bcdaf4ecc90ae9ce63fff873f

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Akademický článek

Acute administration of n-3 rich triglyceride emulsions provides cardioprotection in murine models after ischemia-reperfusion.

Autor: Hylde Zirpoli, Mariane Abdillahi, Nosirudeen Quadri, Radha Ananthakrishnan, Lingjie Wang, Rosa Rosario, Zhengbin Zhu, Richard J Deckelbaum, Ravichandran Ramasamy

Publikováno v: PLoS ONE, Vol 10, Iss 1, p e0116274 (2015)

Dietary n-3 fatty acids (FAs) may reduce cardiovascular disease risk. We questioned whether acute administration of n-3 rich triglyceride (TG) emulsions could preserve cardiac function and decrease injury after ischemia/reperfusion (I/R) insult. We u

Externí odkaz: https://doaj.org/article/8bfdb80efdbd4289a5d6456aec1c00d2

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Akademický článek

Omega-3 fatty acid diglyceride emulsions as a novel injectable acute therapeutic in neonatal hypoxic-ischemic brain injury

Autor: Hylde Zirpoli, Maria Eugenia Bernis, Hemmen Sabir, Denny Joseph Manual Kollareth, James A. Hamilton, Nasi Huang, Jesse Ng, Sergey A. Sosunov, Ben Gaebler, Vadim S. Ten, Richard J. Deckelbaum

Publikováno v: Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116749- (2024)

Hypoxic-ischemic encephalopathy (HIE), resulting from a lack of blood flow and oxygen before or during newborn delivery, is a leading cause of cerebral palsy and neurological disability in children. Therapeutic hypothermia (TH), the current standard

Externí odkaz: https://doaj.org/article/09898beb26164f4ab55eb2a4d98f52a4

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Akademický článek

N-3 fatty acid rich triglyceride emulsions are neuroprotective after cerebral hypoxic-ischemic injury in neonatal mice.

Autor: Jill J Williams, Korapat Mayurasakorn, Susan J Vannucci, Christopher Mastropietro, Nicolas G Bazan, Vadim S Ten, Richard J Deckelbaum

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e56233 (2013)

We questioned if acute administration of n-3 fatty acids (FA) carried in n-3 rich triglyceride (TG) emulsions provides neuroprotection in neonatal mice subjected to hypoxic-ischemic (H/I) brain injury. We examined specificity of FA, optimal doses, an

Externí odkaz: https://doaj.org/article/97fb6e391834423da23d251a61cdd352

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Akademický článek

Acute Injection of Omega-3 Triglyceride Emulsion Provides Very Similar Protection as Hypothermia in a Neonatal Mouse Model of Hypoxic-Ischemic Brain Injury

Autor: Denny Joseph Manual Kollareth, Hylde Zirpoli, Vadim S. Ten, Richard J. Deckelbaum

Publikováno v: Frontiers in Neurology, Vol 11 (2021)

Therapeutic hypothermia (HT) is a currently accepted treatment for neonatal asphyxia and is a promising strategy in adult stroke therapy. We previously reported that acute administration of docosahexaenoic acid (DHA) triglyceride emulsion (tri-DHA) p

Externí odkaz: https://doaj.org/article/03664fea1d354677806e16f8d2ffc468

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Akademický článek

Radiolabeled cholesteryl ethers: A need to analyze for biological stability before use

Autor: Denny Joseph Manual Kollareth, Chuchun L. Chang, Inge H. Hansen, Richard J. Deckelbaum

Publikováno v: Biochemistry and Biophysics Reports, Vol 13, Iss , Pp 1-6 (2018)

Radiolabeled cholesteryl ethers are widely used as non-metabolizable tracers for lipoproteins and lipid emulsions in a variety of in vitro and in vivo experiments. Since cholesteryl ethers do not leave cells after uptake and are not hydrolyzed by mam

Externí odkaz: https://doaj.org/article/ffd856c94a7142c1863167cbdecceb8f

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Assessing the safety of bioactive ingredients in infant formula that affect the immune system: recommendations from an expert panel

Autor: Emily A Callahan, Joshua D. Milner, Richard J. Deckelbaum, Josef Neu, Ronald E. Kleinman, John C. Wallingford, Kirsi M. Järvinen, Frank R Greer, Olle Hernell, Catherine J. Field, Talal A. Chatila, Kinga K. Smolen

Publikováno v: The American Journal of Clinical Nutrition. 115:570-587

Bioactive ingredients for infant formula have been sought to reduce disparities in health outcomes between breastfed and formula-fed infants. Traditional food safety methodologies have limited ability to assess some bioactive ingredients. It is diffi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bcae475f80d4866106e39d7248f119
https://doi.org/10.1093/ajcn/nqab346

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The Critical Need for Pooled Data on Coronavirus Disease 2019 in African Children: An AFREhealth Call for Action Through Multicountry Research Collaboration

Autor: Onesmus Gachuno, Michel P Hermans, Prisca Olabisi Adejumo, Oma Amadi, Jean B. Nachega, Aster Tsegaye, Mary Glenn Fowler, Rhoderick Machekano, Nancy Mongweli, Serge Zigabe, Michel Tshiasuma Pipo, Lynne M. Mofenson, Lawal Waisu Umar, Hellen Tukamuhebwa Aanyu, John O Otshudiema, Asara M Abdullahi, Alfred K Mteta, Nadia A. Sam-Agudu, Léon Tshilolo, Jean-Marie Ntumba Kayembe, Refiloe Masekela, Aishatu Mohammed Jibril, Marieke M. van der Zalm, Christian Bongo-Pasi Nswe, Evans Kofi Agbeno, Angela Dramowski, Birhanu Teshome Ayele, Emilia Virginia Noormahomed, Umar Mohammed Umar, Ameena Ebrahim Goga, Emmanuella Amoako, Andrew Redfern, Peter Nyasulu, Don Jethro Mavungu Landu, Richard J. Deckelbaum, Fatima Suleman, Liliane N. Byamungu, Nelson K. Sewankambo, Jean-Jacques Muyembe-Tamfum, Alimuddin Zumla, Abdon Mukalay, Elizabeth Agyare, Daniel Katuashi Ishoso, Adolescents, Philippa Musoke, Edward J Mills, Placide Mbala-Kingebeni, John Kinuthia, Mariana Kruger, Helena Rabie

Publikováno v: Clinical Infectious Diseases

Globally, there are prevailing knowledge gaps in the epidemiology, clinical manifestations, and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among children and adolescents; and these gaps are especially wide in A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e2298d430a0b201d88db5e72de648a
https://doi.org/10.1093/cid/ciab142

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