Zobrazeno 1 - 10
of 514
pro vyhledávání: '"Richard J Clark"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
TLQP-21 is a 21-amino acid neuropeptide derived from the VGF precursor protein. TLQP-21 is expressed in the nervous system and neuroendocrine glands, and demonstrates pleiotropic roles including regulating metabolism, nociception and microglial funct
Externí odkaz:
https://doaj.org/article/3e34e826125b49e68e8a93beb3225f67
Autor:
Hooman Mirzaee, Emily Ariens, James Booth, Lilia C. Carvalhais, Mark A.T. Blaskovich, Richard J. Clark, Peer M. Schenk
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 31, Iss , Pp S2- (2022)
Externí odkaz:
https://doaj.org/article/1d7271bfd86e4467af461554ff702dce
Autor:
Vinod Kumar, John D. Lee, Richard J. Clark, Peter G. Noakes, Stephen M. Taylor, Trent M. Woodruff
Publikováno v:
ACS Omega, Vol 5, Iss 5, Pp 2345-2354 (2020)
Externí odkaz:
https://doaj.org/article/f29e91c092ab4c299c6708ce5ebc6b12
Autor:
Martin W Lo, Alberto A Amarilla, John D Lee, Eduardo A Albornoz, Naphak Modhiran, Richard J Clark, Vito Ferro, Mohit Chhabra, Alexander A Khromykh, Daniel Watterson, Trent M Woodruff
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 8, Pp n/a-n/a (2022)
Abstract Objectives To determine whether SARS‐CoV‐2 can trigger complement activation, the pathways that are involved and the functional significance of the resultant effect. Methods SARS‐CoV‐2 was inoculated into a human lepirudin‐anticoag
Externí odkaz:
https://doaj.org/article/fce3333fc3fd462e95eb7a2ae93b9833
Autor:
Kirat K. Chand, Kah Meng Lee, Nickolas A. Lavidis, Manuel Rodriguez-Valle, Hina Ijaz, Johannes Koehbach, Richard J. Clark, Ala Lew-Tabor, Peter G. Noakes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1422b4e514b4457f84631a3e5f573c5f
Autor:
Daniela Goncalves Monteiro, Gautam Rishi, Declan M. Gorman, Guillaume Burnet, Randy Aliyanto, K. Johan Rosengren, David M. Frazer, V. Nathan Subramaniam, Richard J. Clark
Publikováno v:
Molecules, Vol 27, Iss 19, p 6581 (2022)
The protein HFE (homeostatic iron regulator) is a key regulator of iron metabolism, and mutations in HFE underlie the most frequent form of hereditary haemochromatosis (HH-type I). Studies have shown that HFE interacts with transferrin receptor 1 (TF
Externí odkaz:
https://doaj.org/article/755487bbd72842d38be1503a06cd4aa6
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Liver-expressed antimicrobial peptide 2 (LEAP-2), originally described as an antimicrobial peptide, has recently been recognized as an endogenous blocker of growth hormone secretagogue receptor 1a (GHS-R1a). GHS-R1a, also known as ghrelin receptor, i
Externí odkaz:
https://doaj.org/article/853bfd37efd5424e8fea62d89bb9cfec
Autor:
Aaron G. Poth, Francis C.K. Chiu, Sofie Stalmans, Brett R. Hamilton, Yen-Hua Huang, David M. Shackleford, Rahul Patil, Thao T. Le, Meng-Wei Kan, Thomas Durek, Evelien Wynendaele, Bart De Spiegeleer, Andrew K. Powell, Deon J. Venter, Richard J. Clark, Susan A. Charman, David J. Craik
Publikováno v:
Medicine in Drug Discovery, Vol 10, Iss , Pp 100087- (2021)
Chronic pain is an undertreated epidemic affecting quality of life in at least 20% of the global population, and CNS-related side effects, tolerance, and addiction are common features of current medications. α-Conotoxin Vc1.1 potently elicits prolon
Externí odkaz:
https://doaj.org/article/e60af3d636f34e9cace11a1df3b3f934
Publikováno v:
The Auk, 1979 Jul 01. 96(3), 643-644.
Externí odkaz:
https://www.jstor.org/stable/4085584
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Innate immune complement activation generates the C3 and C5 protein cleavage products C3a and C5a, defined classically as anaphylatoxins. C3a activates C3aR, while C5a activates two receptors (C5aR1 and C5aR2) to exert their immunomodulatory activiti
Externí odkaz:
https://doaj.org/article/6cf602609c404216b0c05fe2750006d7