Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Richard J Caselli"'
Autor:
Thomas G Beach, Charles H Adler, Nan Zhang, Geidy E Serrano, Lucia I Sue, Erika Driver-Dunckley, Shayamal H Mehta, Edouard E Zamrini, Marwan N Sabbagh, Holly A Shill, Christine M Belden, David R Shprecher, Richard J Caselli, Eric M Reiman, Kathryn J Davis, Kathy E Long, Lisa R Nicholson, Anthony J Intorcia, Michael J Glass, Jessica E Walker, Michael M Callan, Javon C Oliver, Richard Arce, Richard C Gerkin
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231720 (2020)
Many subjects with neuropathologically-confirmed dementia with Lewy bodies (DLB) are never diagnosed during life, instead being categorized as Alzheimer's disease dementia (ADD) or unspecified dementia. Unrecognized DLB therefore is a critical impedi
Externí odkaz:
https://doaj.org/article/185d07c965d94231a069e5f00e8cea58
Autor:
Michael Malek-Ahmadi, Thomas G Beach, Edward Zamrini, Charles H Adler, Marwan N Sabbagh, Holly A Shill, Sandra A Jacobson, Christine M Belden, Richard J Caselli, Brian K Woodruff, Steven Z Rapscak, Geoffrey L Ahern, Jiong Shi, John N Caviness, Erika Driver-Dunckley, Shyamal H Mehta, David R Shprecher, Bryan M Spann, Pierre Tariot, Kathryn J Davis, Kathy E Long, Lisa R Nicholson, Anthony Intorcia, Michael J Glass, Jessica E Walker, Michael Callan, Jasmine Curry, Brett Cutler, Javon Oliver, Richard Arce, Douglas G Walker, Lih-Fen Lue, Geidy E Serrano, Lucia I Sue, Kewei Chen, Eric M Reiman
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217566 (2019)
BackgroundNeuropathology has demonstrated a high rate of comorbid pathology in dementia due to Alzheimer's disease (ADD). The most common major comorbidity is Lewy body disease (LBD), either as dementia with Lewy bodies (AD-DLB) or Alzheimer's diseas
Externí odkaz:
https://doaj.org/article/20865cfb54d54fcb81882a55f80987e8
Autor:
Oana M. Dumitrascu, MD, MSc, Xin Li, MS, Wenhui Zhu, MS, Bryan K. Woodruff, MD, Simona Nikolova, PhD, Jacob Sobczak, Amal Youssef, MD, Siddhant Saxena, Janine Andreev, Richard J. Caselli, MD, John J. Chen, MD, PhD, Yalin Wang, PhD
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 4, Pp 548-558 (2024)
Objective: To report the development and performance of 2 distinct deep learning models trained exclusively on retinal color fundus photographs to classify Alzheimer disease (AD). Patients and Methods: Two independent datasets (UK Biobank and our ter
Externí odkaz:
https://doaj.org/article/7328428056c84b1e896cd08f0d73c6e3
Autor:
Bolun Li, Jie Shi, Boris A Gutman, Leslie C Baxter, Paul M Thompson, Richard J Caselli, Yalin Wang, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152901 (2016)
The apolipoprotein E (APOE) e4 genotype is a powerful risk factor for late-onset Alzheimer's disease (AD). In the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort, we previously reported significant baseline structural differences in APOE e4
Externí odkaz:
https://doaj.org/article/10b2153c1aa04e309fee058c5e70d8da
Autor:
Frank Schraml, Kewei Chen, Napatkamon Ayutyanont, Roontiva Auttawut, Jessica B S Langbaum, Wendy Lee, Xiaofen Liu, Dan Bandy, Stephanie Q Reeder, Gene E Alexander, Richard J Caselli, Adam S Fleisher, Eric M Reiman, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67163 (2013)
BACKGROUNDWe introduced a hypometabolic convergence index (HCI) to characterize in a single measurement the extent to which a person's fluorodeoxyglucose positron emission tomogram (FDG PET) corresponds to that in Alzheimer's disease (AD). Apolipopro
Externí odkaz:
https://doaj.org/article/700a91dbed794ea5b9db8ef982e21991
Autor:
Nicola J Rutherford, Yong-Jie Zhang, Matt Baker, Jennifer M Gass, Nicole A Finch, Ya-Fei Xu, Heather Stewart, Brendan J Kelley, Karen Kuntz, Richard J P Crook, Jemeen Sreedharan, Caroline Vance, Eric Sorenson, Carol Lippa, Eileen H Bigio, Daniel H Geschwind, David S Knopman, Hiroshi Mitsumoto, Ronald C Petersen, Neil R Cashman, Mike Hutton, Christopher E Shaw, Kevin B Boylan, Bradley Boeve, Neill R Graff-Radford, Zbigniew K Wszolek, Richard J Caselli, Dennis W Dickson, Ian R Mackenzie, Leonard Petrucelli, Rosa Rademakers
Publikováno v:
PLoS Genetics, Vol 4, Iss 9, p e1000193 (2008)
The TAR DNA-binding protein 43 (TDP-43) has been identified as the major disease protein in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin inclusions (FTLD-U), defining a novel class of neurodegenerative cond
Externí odkaz:
https://doaj.org/article/3cae87e0864343239646260c2e500bfe
Autor:
Maurizio Bergamino, Anna Burke, Marwan N. Sabbagh, Richard J. Caselli, Leslie C. Baxter, Ashley M. Stokes
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionCognitive impairment (CI) due to Alzheimer’s disease (AD) encompasses a decline in cognitive abilities and can significantly impact an individual’s quality of life. Early detection and intervention are crucial in managing CI, both in
Externí odkaz:
https://doaj.org/article/620da2248c1248d49ec4f474e5a61eca
Autor:
Michael Malek-Ahmadi, Yi Su, Valentina Ghisays, Ji Luo, Vivek Devadas, Yinghua Chen, Wendy Lee, Hillary Protas, Kewei Chen, Henrik Zetterberg, Kaj Blennow, Richard J. Caselli, Eric M. Reiman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract Background Plasma neurofilament light (NfL) is an indicator of neurodegeneration and/or neuroaxonal injury in persons with Alzheimer’s disease (AD) and a wide range of other neurological disorders. Here, we characterized and compared plasm
Externí odkaz:
https://doaj.org/article/1e0baaa1053d468dacf6da005802ca91
Autor:
Thomas G Beach, Lucia I Sue, Sarah Scott, Anthony J Intorcia, Jessica E Walker, Richard A Arce, Michael J Glass, Claryssa I Borja, Madison P Cline, Spencer J Hemmingsen, Sanaria Qiji, Analisa Stewart, Kayleigh N Martinez, Addison Krupp, Rylee McHattie, Monica Mariner, Ileana Lorenzini, Angela Kuramoto, Kathy E Long, Cécilia Tremblay, Richard J Caselli, Bryan K Woodruff, Steven Z Rapscak, Christine M Belden, Danielle Goldfarb, Parichita Choudhury, Erika D Driver-Dunckley, Shyamal H Mehta, Marwan N Sabbagh, Holly A Shill, Alireza Atri, Charles H Adler, Geidy E Serrano
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 82:457-466
Cerebral white matter rarefaction (CWMR) was considered by Binswanger and Alzheimer to be due to cerebral arteriolosclerosis. Renewed attention came with CT and MR brain imaging, and neuropathological studies finding a high rate of CWMR in Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7a948f73150d9128a670c619f96e0e
https://doi.org/10.1093/jnen/nlad026
https://doi.org/10.1093/jnen/nlad026
Autor:
Richard J, Caselli, Yinghua, Chen, Kewei, Chen, Robert J, Bauer, Dona E C, Locke, Bryan K, Woodruff
Publikováno v:
J Alzheimers Dis
Background: Older age is a major risk factor for severe COVID-19 disease which has been associated with a variety of neurologic complications, both acutely and chronically. Objective: We sought to determine whether milder COVID-19 disease in older vu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72b13f246a96a070d74efb7a2b4d93a
https://doi.org/10.3233/jad-220435
https://doi.org/10.3233/jad-220435