Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Richard J Bram"'
Autor:
Ying Zhang, Justin Gundelach, Lonnie D Lindquist, Darren J Baker, Jan van Deursen, Richard J Bram
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224172 (2019)
T cell acute lymphoblastic leukemia (T-ALL) is a serious hematologic malignancy that occurs in children and young adults. Current therapies include intensive chemotherapy and ionizing radiation that preferentially kill malignant cells. Unfortunately,
Externí odkaz:
https://doaj.org/article/c7dc5ecea4734e388ada123b68d909ac
Autor:
Jae Won Choi, Shari L Sutor, Lonn Lindquist, Glenda L Evans, Benjamin J Madden, H Robert Bergen, Theresa E Hefferan, Michael J Yaszemski, Richard J Bram
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000750 (2009)
Osteogenesis Imperfecta (OI) is a human syndrome characterized by exquisitely fragile bones due to osteoporosis. The majority of autosomal dominant OI cases result from point or splice site mutations in the type I collagen genes, which are thought to
Externí odkaz:
https://doaj.org/article/6198cc03b1f54266bae27fc9975b998a
Autor:
Haotian Zhao, Olivier Ayrault, Michael D. Talyor, Ulrich Schüller, Richard J. Bram, Kameswaran Surendran, Indra Chandrasekar, Stephanie Puget, Erliang Zeng, Xijin Ge, Alex H. Heglin, Xin Wang, Diane M. Maher, Slobodan Macura, Justin H. Gundelach, Amanda M. Schaefer, Antoine Forget, A. Sorana Morrissy, Hasitha Premathilake, Laure Bihannic, Samuel D.R. Dooyema, Katie B. Grausam
This table provide supplemental information on the results of ChIP-seq and gene expression analyses of primary and spinal metastatic tumors in MAP mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856331407f22976062816d2b1b7d120a
https://doi.org/10.1158/0008-5472.22415012.v1
https://doi.org/10.1158/0008-5472.22415012.v1
Autor:
Haotian Zhao, Olivier Ayrault, Michael D. Talyor, Ulrich Schüller, Richard J. Bram, Kameswaran Surendran, Indra Chandrasekar, Stephanie Puget, Erliang Zeng, Xijin Ge, Alex H. Heglin, Xin Wang, Diane M. Maher, Slobodan Macura, Justin H. Gundelach, Amanda M. Schaefer, Antoine Forget, A. Sorana Morrissy, Hasitha Premathilake, Laure Bihannic, Samuel D.R. Dooyema, Katie B. Grausam
This file provides illustration of supplemental experimental results and explanation of data presented. Supplemental Figure 1 Analysis of gene expression in CAG-A1Z transgenic mice. Supplemental Figure 2 Normal cerebellar development in Atoh1 transge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646048ca6c3e852d7d38f68afc44e3bf
https://doi.org/10.1158/0008-5472.22415009.v1
https://doi.org/10.1158/0008-5472.22415009.v1
Autor:
Haotian Zhao, Olivier Ayrault, Michael D. Talyor, Ulrich Schüller, Richard J. Bram, Kameswaran Surendran, Indra Chandrasekar, Stephanie Puget, Erliang Zeng, Xijin Ge, Alex H. Heglin, Xin Wang, Diane M. Maher, Slobodan Macura, Justin H. Gundelach, Amanda M. Schaefer, Antoine Forget, A. Sorana Morrissy, Hasitha Premathilake, Laure Bihannic, Samuel D.R. Dooyema, Katie B. Grausam
This section provides detailed information on experimental procedures and data analysis methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8eb04cb0166aa4efb32d8f483115f7
https://doi.org/10.1158/0008-5472.22415024.v1
https://doi.org/10.1158/0008-5472.22415024.v1
Autor:
Haotian Zhao, Olivier Ayrault, Michael D. Talyor, Ulrich Schüller, Richard J. Bram, Kameswaran Surendran, Indra Chandrasekar, Stephanie Puget, Erliang Zeng, Xijin Ge, Alex H. Heglin, Xin Wang, Diane M. Maher, Slobodan Macura, Justin H. Gundelach, Amanda M. Schaefer, Antoine Forget, A. Sorana Morrissy, Hasitha Premathilake, Laure Bihannic, Samuel D.R. Dooyema, Katie B. Grausam
Medulloblastoma arising from the cerebellum is the most common pediatric brain malignancy, with leptomeningeal metastases often present at diagnosis and recurrence associated with poor clinical outcome. In this study, we used mouse medulloblastoma mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e11fa39ef5c0deb112ac2eb8a77e9b8
https://doi.org/10.1158/0008-5472.c.6509144.v1
https://doi.org/10.1158/0008-5472.c.6509144.v1
Autor:
Haotian Zhao, Olivier Ayrault, Michael D. Talyor, Ulrich Schüller, Richard J. Bram, Kameswaran Surendran, Indra Chandrasekar, Stephanie Puget, Erliang Zeng, Xijin Ge, Alex H. Heglin, Xin Wang, Diane M. Maher, Slobodan Macura, Justin H. Gundelach, Amanda M. Schaefer, Antoine Forget, A. Sorana Morrissy, Hasitha Premathilake, Laure Bihannic, Samuel D.R. Dooyema, Katie B. Grausam
This table provides sequence information for primers and probes used in RT-qPCR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b996e9b930e83755a339e0f01e6bf9
https://doi.org/10.1158/0008-5472.22415021.v1
https://doi.org/10.1158/0008-5472.22415021.v1
Glioblastoma multiforme is an aggressive, treatment-refractory type of brain tumor for which effective therapeutic targets remain important to identify. Here, we report that cyclophilin B (CypB), a prolyl isomerase residing in the endoplasmic reticul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55575f92d3157916d29b1c1eee756384
https://doi.org/10.1158/0008-5472.c.6505772
https://doi.org/10.1158/0008-5472.c.6505772
PDF file - 1026K, Figure S1. Pharmacological inhibition of Cyclophilin B reduces glioblastoma cell survival. Figure S2. Inhibition of MAPK signaling prevents CypB knockdown-induced senescence. Figure S3. Cyclophilin B controls p53 expression. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1c527965d9752a4f712acf93bc8130
https://doi.org/10.1158/0008-5472.22401137.v1
https://doi.org/10.1158/0008-5472.22401137.v1