Zobrazeno 1 - 10
of 425
pro vyhledávání: '"Richard J Bold"'
Autor:
Lauren M. Perry, MD, Robert J. Canter, MD, Cameron E. Gaskill, MD, MPH, Richard J. Bold, MD, MBA
Publikováno v:
Surgery Open Science, Vol 16, Iss , Pp 198-204 (2023)
Introduction: Pancreatic cancer (PC) surgery has been associated with improved outcomes and value when performed at high-volume centers (HVC; ≥20 surgeries annually) compared to low-volume centers (LVC). Some have used these differences to suggest
Externí odkaz:
https://doaj.org/article/7758eb4898ba4962bcd03c8b5023d386
Autor:
Sarah S. Wang, Madison L. Hall, EunJung Lee, Soon-Chan Kim, Neha Ramesh, Sang Hyub Lee, Jin-Young Jang, Richard J. Bold, Ja-Lok Ku, Chang-Il Hwang
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109414- (2024)
Summary: In pancreatic ductal adenocarcinoma (PDAC), no recurrent metastasis-specific mutation has been found, suggesting that epigenetic mechanisms, such as DNA methylation, are the major contributors of late-stage disease progression. Here, we perf
Externí odkaz:
https://doaj.org/article/b585b1d868174aa89f6764d299282f5f
Autor:
Demin Cai, Junjian Wang, Bei Gao, Jin Li, Feng Wu, June X. Zou, Jianzhen Xu, Yuqian Jiang, Hongye Zou, Zenghong Huang, Alexander D. Borowsky, Richard J. Bold, Primo N. Lara, Jian Jian Li, Xinbin Chen, Kit S. Lam, Ka-Fai To, Hsing-Jien Kung, Oliver Fiehn, Ruqian Zhao, Ronald M. Evans, Hong-Wu Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Enhanced cholesterol biosynthesis is associated with cancer progression. Here the authors identify the nuclear receptor RORγ as a novel master regulator of cholesterol metabolism in triple negative breast cancer (TNBC) and find that RORγ small-mole
Externí odkaz:
https://doaj.org/article/985e83249405455e850f73d41a842e97
Autor:
Sean J. Judge, Jingran Ji, James Liu, Manmeet Kaur, Edward Kim, Jun Gong, Kit W. Tam, Amanda R. Kirane, Sepideh Gholami, Robert J. Canter, Richard J. Bold, Alexandra Gangi, Marwan Fakih, May Cho
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The role of palliative surgery in the management of acute complications in patients with disseminated malignancy remains controversial given the complexity of assessing acute surgical risk and long-term oncologic outcome. With the emergence of checkp
Externí odkaz:
https://doaj.org/article/d5f3b66e41fc46c8b45a0811f98cb86a
Autor:
Sarah B. Bateni, Alicia A. Gingrich, Susan L. Stewart, Frederick J. Meyers, Richard J. Bold, Robert J. Canter
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Malignant bowel obstruction (MBO) is often a terminal event in end-stage cancer patients. The decision to intervene surgically is complex, given the risk of harm in patients with a limited lifespan. Therefore, we sought to compare
Externí odkaz:
https://doaj.org/article/36b8de133d94414ab2ea5126d4e640f0
Publikováno v:
Surgery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08b86ced3012adb2e88112d82ab430df
https://doi.org/10.1016/j.surg.2023.02.030
https://doi.org/10.1016/j.surg.2023.02.030
Autor:
Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner
Shows the biodistribution data for [18F]αvβ6-BP in mice bearing paired αvβ6-expressing DX3puroβ6 and non-αvβ6-expressing DX3puro xenograft tumors at 1, 2 and 4 h p.i. and at 1 h p.i. after pre-administration of blocking peptide. Tissue uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78af266f4811fbf64af07f8e9bde8240
https://doi.org/10.1158/1078-0432.22467603.v1
https://doi.org/10.1158/1078-0432.22467603.v1
Autor:
Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner
Purpose:The study was undertaken to develop and evaluate the potential of an integrin αvβ6-binding peptide (αvβ6-BP) for noninvasive imaging of a diverse range of malignancies with PET.Experimental Design:The peptide αvβ6-BP was prepared on sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405e7502a084ce6f15ffd02e8f1fe0fa
https://doi.org/10.1158/1078-0432.c.6526695.v1
https://doi.org/10.1158/1078-0432.c.6526695.v1
Autor:
Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner
Shows the in vivo stability of [18F]αvβ6-BP in human blood. Representative radio-HPLC of blood sample taken 30 min post injection. Top: Sample only; bottom: sample spiked with [18F]αvβ6-BP. X-axis: retention time [min]; Y-axis: detector response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c46e86ac37f7576a9f3f73d85ecbe1
https://doi.org/10.1158/1078-0432.22467612.v1
https://doi.org/10.1158/1078-0432.22467612.v1
Autor:
Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner
Describes additional methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df5ae43674db2d9248b8862f34eef09
https://doi.org/10.1158/1078-0432.22467609.v1
https://doi.org/10.1158/1078-0432.22467609.v1