Výsledky vyhledávání - "Richard J Betts"

Akademický článek

Partial depletion of natural CD4⁺CD25⁺ regulatory T cells with anti-CD25 antibody does not alter the course of acute influenza A virus infection.

Autor: Richard J Betts, Adrian W S Ho, David M Kemeny

Publikováno v: PLoS ONE, Vol 6, Iss 11, p e27849 (2011)

Foxp3⁺CD4⁺ regulatory T cells represent a T cell subset with well-characterized immunosuppressive effects during immune homeostasis and chronic infections, and there is emerging evidence to suggest these cells temper pulmonary inflammation in res

Externí odkaz: https://doaj.org/article/34a8023c91f7401a8be6ee9e31d28322

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Akademický článek

Skin microbiome differentiates into distinct cutotypes with unique metabolic functions upon exposure to polycyclic aromatic hydrocarbons

Autor: Marcus H. Y. Leung, Xinzhao Tong, Zhiyong Shen, Shicong Du, Philippe Bastien, Brice M. R. Appenzeller, Richard J. Betts, Sakina Mezzache, Nasrine Bourokba, Nukhet Cavusoglu, Luc Aguilar, Namita Misra, Cécile Clavaud, Patrick K. H. Lee

Publikováno v: Microbiome, Vol 11, Iss 1, Pp 1-14 (2023)

Abstract Background The effects of air pollutants, particularly polycyclic aromatic hydrocarbons (PAHs), on the skin microbiome remain poorly understood. Thus, to better understand the interplay between air pollutants, microbiomes, and skin condition

Externí odkaz: https://doaj.org/article/53497227b09d4efb83122f6fd0a6e847

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Glycosaminoglycans: Sweet as Sugar Targets for Topical Skin Anti-Aging

Autor: Siew Tein Wang, Boon Hoe Neo, Richard J. Betts

Publikováno v: Clinical, Cosmetic and Investigational Dermatology

Glycosaminoglycans (GAGs) are long, linear polysaccharides comprised of repeating disaccharide units with pleiotropic biological functions, with the non-sulfated GAG hyaluronic acid (HA), and sulfated GAGs dermatan sulfate, chondroitin sulfate, hepar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd84acd5bb84de5a15b4cf0eca2f6196
http://europepmc.org/articles/PMC8449875

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Photo-aging evaluation - In vitro biological endpoints combined with collagen density assessment with multi-photon microscopy

Autor: Yang Liu, Juan Liu, Hongbin Dai, Ranran Wang, Amy Hsiao, Wei Wang, Richard J. Betts, Claire Marionnet, Francoise Bernerd, Jie Qiu

Publikováno v: Journal of dermatological science. 105(1)

Ultraviolet exposure has profound effect on the dermal connective tissue of human skin.We aimed to develop and validate an evaluation method/methodology using a full-thickness reconstructed skin model, to assess the anti-photoaging efficacy of cosmet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8985af746d75ba02dfa2563ebdbf44e3
https://pubmed.ncbi.nlm.nih.gov/34952763

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Polycyclic aromatic hydrocarbons regulate the pigmentation pathway and induce DNA damage responses in keratinocytes, a process driven by systemic immunity

Autor: Siew Tein Wang, Namita Misra, Tze Khee Chan, Nasrine Bourokba, Rebecca Y.X. Lim, Boon Hoe Neo, Richard J. Betts, Vedula Krishna, Hyoju Kim, Diah Bramono, Shawn Lim

Publikováno v: Journal of dermatological science. 104(2)

Background Urban pollution is correlated with an increased prevalence of skin pigmentation disorders, however the physiological processes underlying this association are unclear. Objectives To delineate the relationship between polycyclic aromatic hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb40163aa3608ccdf945b088b400d43c
https://pubmed.ncbi.nlm.nih.gov/34690024

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Changes of the human skin microbiota upon chronic exposure to polycyclic aromatic hydrocarbon pollutants

Autor: Marcus H. Y. Leung, Lionel Breton, Patrick K. H. Lee, Sakina Mezzache, Nasrine Bourokba, Cécile Clavaud, Richard J. Betts, Brice M.R. Appenzeller, Philippe Bastien, Arthur Tenenhaus, Xinzhao Tong, Jing Li, Florent Guinot

Publikováno v: Microbiome
Microbiome, BioMed Central, 2020, 8 (1), ⟨10.1186/s40168-020-00874-1⟩
Microbiome, 2020, 8 (1), ⟨10.1186/s40168-020-00874-1⟩
Microbiome, Vol 8, Iss 1, Pp 1-17 (2020)

Background Polycyclic aromatic hydrocarbons (PAHs) are of environmental and public health concerns and contribute to adverse skin attributes such as premature skin aging and pigmentary disorder. However, little information is available on the potenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04646e4daae3cc2a62509a84665c012
https://hal.archives-ouvertes.fr/hal-03111196

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Contact sensitizers trigger human CD1-autoreactive T-cell responses

Autor: Silvia Teissier, Adrijana Perkovic, Gennaro De Libero, Richard J. Betts, Kaddy Camara, Subhashree Mahapatra, Aurélia Del Bufalo, Lucia Mori, Amy R. Howell

Publikováno v: European Journal of Immunology. 47:1171-1180

Allergic contact dermatitis is a primarily T-cell-mediated inflammatory skin disease induced by exposure to small molecular-weight haptens, which covalently bind to proteins. The abundance of cutaneous T cells that recognize CD1a antigen-presenting m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d1c715c6462e20a6fab1ee15e84e98
https://doi.org/10.1002/eji.201746939

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Validation of a predictive method for sunscreen formula evaluation using gene expression analysis in a Chinese reconstructed full-thickness skin model

Autor: H. Dai, H. Nocairi, C. Ding, Jie Qiu, Richard J. Betts, X. He, R. Wang, Claire Marionnet, X. Wang, Françoise Bernerd, Y. Liu, Z. Cai, Emilie Planel

Publikováno v: International journal of cosmetic science. 41(2)

This study aimed to establish a predictive in vitro method for assessing the photoprotective properties of sunscreens using a reconstructed full-thickness skin model.A full-thickness skin model reconstructed with human fibroblasts and keratinocytes i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75a74211446afa01a66a1574237a921
https://pubmed.ncbi.nlm.nih.gov/30719735

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Polygonum multiflorum Radix extract protects human foreskin melanocytes from oxidative stress in vitro and potentiates hair follicle pigmentation ex vivo

Autor: Jean-François Michelet, Ping Wang, Ishak Benkhalifa, Xuezhu Tan, Stephane Commo, Jie Qiu, Richard J. Betts, Severine Jeulin, Joan Eilstein, Peggy Sextius, Marco Massironi

Publikováno v: International journal of cosmetic science. 39(4)

Objective To examine the ability of an extract from traditional Chinese medicine, Polygonum multiflorum Radix, to protect melanocyte viability from oxidative stress, a key mechanism in the initiation and progression of hair greying. Methods To assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2c2207090ac04b64be9ae4dc9b6218
https://pubmed.ncbi.nlm.nih.gov/28109001

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Influenza A Virus Infection Results in a Robust, Antigen-Responsive, and Widely Disseminated Foxp3 + Regulatory T Cell Response

Autor: David M. Kemeny, Adrian W. S. Ho, Fei Chuin Lew, Nayana Prabhu, Richard J. Betts, Paul Edward Hutchinson, Olaf Rötzschke, Paul A. MacAry

Publikováno v: Journal of Virology. 86:2817-2825

Foxp3 + CD4 + regulatory T cells (Tregs) represent a highly suppressive T cell subset with well-characterized immunosuppressive effects during immune homeostasis and chronic infections, although the role of these cells in acute viral infections is po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f798010b80ed65b8234bca0ae2cc946c
https://doi.org/10.1128/jvi.05685-11

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