Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Richard J Alsop"'
Autor:
Richard J Alsop, Asfia Soomro, Yuchen Zhang, Marc Pieterse, Ayodele Fatona, Kimberly Dej, Maikel C Rheinstädter
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149619 (2016)
We report the biophysical characterization of hair from a patient with a de novo ribosomopathy. The patient was diagnosed with a mutation on gene RPS23, which codes for a protein which comprises part of the 40S subunit of the ribosome. The patient pr
Externí odkaz:
https://doaj.org/article/b87ff20c0a1f42e39c74cfe4aa39d4d5
Autor:
Matthew A Barrett, Songbo Zheng, Golnaz Roshankar, Richard J Alsop, Randy K R Belanger, Chris Huynh, Norbert Kučerka, Maikel C Rheinstädter
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34357 (2012)
We studied the interaction of Aspirin (acetylsalicylic acid) with lipid membranes using x-ray diffraction for bilayers containing up to 50 mol% of aspirin. From 2D x-ray intensity maps that cover large areas of reciprocal space we determined the posi
Externí odkaz:
https://doaj.org/article/d01dee1dcc0e442a9595ba51aa0221cf
Autor:
Richard J. Alsop, Sebastian Himbert, Alexander Dhaliwal, Karin Schmalzl, Maikel C. Rheinstädter
Publikováno v:
Royal Society Open Science, Vol 5, Iss 2 (2018)
Local structure and dynamics of lipid membranes play an important role in membrane function. The diffusion of small molecules, the curvature of lipids around a protein and the existence of cholesterol-rich lipid domains (rafts) are examples for the m
Externí odkaz:
https://doaj.org/article/66c3d39f1bee4b83bff05f5957be5ab6
Autor:
Richard J. Alsop, Ivan Urosev, Maikel C. Rheinstädter, Helen Dorrington, Emilia Bakaic, Trevor Gilbert, Nicola Muzzin, Todd Hoare
Publikováno v:
ACS Applied Polymer Materials. 1:369-380
The physicochemical properties of injectable hydrogels are typically modified by altering the chemistry of the precursor polymer and/or the amount or type of cross-linker, both of which can lead to hydrogels with altered mechanics, swelling, degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907d089d71989317c696669111ed584f
https://doi.org/10.1021/acsapm.8b00085
https://doi.org/10.1021/acsapm.8b00085
Publikováno v:
Membranes, Vol 7, Iss 3, p 49 (2017)
Amyloid- β aggregates play a causative role in Alzheimer’s disease. These aggregates are a product of the physical environment provided by the basic neuronal membrane, composed of a lipid bilayer. The intrinsic properties of the lipid bilayer allo
Externí odkaz:
https://doaj.org/article/fd6c1aeb88e1462a973e0dc3d44c2150
Autor:
Viviana Cristiglio, Sebastian Himbert, Maikel C. Rheinstädter, Giovanna Fragneto, Richard J. Alsop, Lili Zhang
Publikováno v:
Soft matter. 16(42)
The potency of anesthesia was directly linked to the partitioning of the drug molecules in cell membranes by Meyer and Overton. Many molecules interact with lipid bilayers and lead to structural and functional changes. It remains an open question whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dd39731285d9f9c426323823603554
https://pubmed.ncbi.nlm.nih.gov/32869047
https://pubmed.ncbi.nlm.nih.gov/32869047
Autor:
Sebastian Himbert, Adam P. Hitchcock, Jennifer Tang, An-Chang Shi, Maikel C. Rheinstädter, Adree Khondker, Richard J. Alsop
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
The formation of amyloid-β plaques is one of the hallmarks of Alzheimer’s disease. The presence of an amphiphatic cell membrane can accelerate the formation of amyloid-β aggregates, making it a potential druggable target to delay the progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8f31422077a9af64ef23542b5927cc
http://link.springer.com/article/10.1038/s41598-018-30431-8
http://link.springer.com/article/10.1038/s41598-018-30431-8
Autor:
Richard J. Alsop, Pia Lenzig, Rahul Rimal, Adree Khondker, Dominik Wiemuth, Maikel C. Rheinstädter, Natalie N. Gervasi, Sylvia Joussen, Axel Schmidt, Stefan Gründer
Publikováno v:
Biophysical Journal. 114:1321-1335
The bile acid-sensitive ion channel is activated by amphiphilic substances such as bile acids or artificial detergents via membrane alterations; however, the mechanism of membrane sensitivity of the bile acid-sensitive ion channel is not known. It ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac59876f8f898637ec65f85a3c17a8f
https://doi.org/10.1016/j.bpj.2018.01.028
https://doi.org/10.1016/j.bpj.2018.01.028
Autor:
Eva Mueller, Walter Richtering, Maikel C. Rheinstädter, Richard J. Alsop, Andrea Scotti, Todd Hoare, Markus Bleuel
Publikováno v:
Langmuir. 34:1601-1612
The internal morphology of temperature-responsive degradable poly(N-isopropylacrylamide) (PNIPAM) microgels formed via an aqueous self-assembly process based on hydrazide and aldehyde-functionalized PNIPAM oligomers is investigated. A combination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78245c4ce1b82adec73fe07ace38d853
https://doi.org/10.1021/acs.langmuir.7b03664
https://doi.org/10.1021/acs.langmuir.7b03664
Autor:
Maikel C. Rheinstädter, Todd Hoare, Jose M. Moran-Mirabal, Richard J. Alsop, Trevor Gilbert, Mouhanad Babi
Publikováno v:
ACS Applied Materials & Interfaces. 9:42179-42191
Herein, we comprehensively investigate the internal morphology of fully injectable interpenetrating networks (IPNs) prepared via coextrusion of functionalized precursor polymer solutions based on thermoresponsive poly(N-isopropylacrylamide) (PNIPAM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2f7c9664f79c6d5f63c96f079fe70d
https://doi.org/10.1021/acsami.7b11637
https://doi.org/10.1021/acsami.7b11637