Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Richard J Alsop"'
Autor:
Richard J. Alsop, Sebastian Himbert, Alexander Dhaliwal, Karin Schmalzl, Maikel C. Rheinstädter
Publikováno v:
Royal Society Open Science, Vol 5, Iss 2 (2018)
Local structure and dynamics of lipid membranes play an important role in membrane function. The diffusion of small molecules, the curvature of lipids around a protein and the existence of cholesterol-rich lipid domains (rafts) are examples for the m
Externí odkaz:
https://doaj.org/article/66c3d39f1bee4b83bff05f5957be5ab6
Publikováno v:
Membranes, Vol 5, Iss 4, Pp 824-843 (2015)
Amyloid-β peptides interact with cell membranes in the human brain and are associated with neurodegenerative diseases, such as Alzheimer’s disease. An emerging explanation of the molecular mechanism, which results in neurodegeneration, places the
Externí odkaz:
https://doaj.org/article/33b9e67382f24c86a5ea8454a45f8c78
Publikováno v:
Membranes, Vol 5, Iss 4, Pp 532-552 (2015)
NIt was recently reported that static magnetic fields increase lipid order in the hydrophobic membrane core of dehydrated native plant plasma membranes [Poinapen, Soft Matter 9:6804-6813, 2013]. As plasma membranes are multicomponent, highly complex
Externí odkaz:
https://doaj.org/article/27b2aa9b9e7e49d2adf66ba7496dd8af
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 2, Iss 2, Pp 125-140 (2015)
There is an urgent quest for improved heart health. Here, we review how neutron radiation can provide insight into the molecular basis of heart health. Lower cholesterol, a daily intake of aspirin and supplemental vitamin E are argued to all improve
Externí odkaz:
https://doaj.org/article/7cb566f4504e4d90bdb6024e2b28371f
Autor:
Richard J Alsop, Asfia Soomro, Yuchen Zhang, Marc Pieterse, Ayodele Fatona, Kimberly Dej, Maikel C Rheinstädter
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149619 (2016)
We report the biophysical characterization of hair from a patient with a de novo ribosomopathy. The patient was diagnosed with a mutation on gene RPS23, which codes for a protein which comprises part of the 40S subunit of the ribosome. The patient pr
Externí odkaz:
https://doaj.org/article/b87ff20c0a1f42e39c74cfe4aa39d4d5
Publikováno v:
PeerJ, Vol 3, p e1296 (2015)
The hair is a filamentous biomaterial consisting of the cuticle, the cortex and the medulla, all held together by the cell membrane complex. The cortex mostly consists of helical keratin proteins that spiral together to form coiled-coil dimers, inter
Externí odkaz:
https://doaj.org/article/bcb1a507faa94adc8a6767c2e02bfee2
Autor:
Richard J. Alsop, Ivan Urosev, Maikel C. Rheinstädter, Helen Dorrington, Emilia Bakaic, Trevor Gilbert, Nicola Muzzin, Todd Hoare
Publikováno v:
ACS Applied Polymer Materials. 1:369-380
The physicochemical properties of injectable hydrogels are typically modified by altering the chemistry of the precursor polymer and/or the amount or type of cross-linker, both of which can lead to hydrogels with altered mechanics, swelling, degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907d089d71989317c696669111ed584f
https://doi.org/10.1021/acsapm.8b00085
https://doi.org/10.1021/acsapm.8b00085
Publikováno v:
Membranes, Vol 7, Iss 3, p 49 (2017)
Amyloid- β aggregates play a causative role in Alzheimer’s disease. These aggregates are a product of the physical environment provided by the basic neuronal membrane, composed of a lipid bilayer. The intrinsic properties of the lipid bilayer allo
Externí odkaz:
https://doaj.org/article/fd6c1aeb88e1462a973e0dc3d44c2150
Autor:
Viviana Cristiglio, Sebastian Himbert, Maikel C. Rheinstädter, Giovanna Fragneto, Richard J. Alsop, Lili Zhang
Publikováno v:
Soft matter. 16(42)
The potency of anesthesia was directly linked to the partitioning of the drug molecules in cell membranes by Meyer and Overton. Many molecules interact with lipid bilayers and lead to structural and functional changes. It remains an open question whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dd39731285d9f9c426323823603554
https://pubmed.ncbi.nlm.nih.gov/32869047
https://pubmed.ncbi.nlm.nih.gov/32869047
Autor:
Matthew A Barrett, Songbo Zheng, Golnaz Roshankar, Richard J Alsop, Randy K R Belanger, Chris Huynh, Norbert Kučerka, Maikel C Rheinstädter
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34357 (2012)
We studied the interaction of Aspirin (acetylsalicylic acid) with lipid membranes using x-ray diffraction for bilayers containing up to 50 mol% of aspirin. From 2D x-ray intensity maps that cover large areas of reciprocal space we determined the posi
Externí odkaz:
https://doaj.org/article/d01dee1dcc0e442a9595ba51aa0221cf