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pro vyhledávání: '"Richard J, Haslam"'
Autor:
Richard J. Haslam
Publikováno v:
Irish University Review. 42:437-441
Publikováno v:
PROTEOMICS. 9:4254-4258
Pleckstrin (plek)-null platelets from a knockout mouse have been shown to be defective in granule secretion, aggregation and actin polymerization. However, the mechanism of plek signaling is currently unknown. Therefore, we sought to identify plek-bi
Publikováno v:
Platelets. 20:446-457
Pleckstrin is a modular platelet protein consisting of N- and C-terminal pleckstrin homology (PH) domains, a central dishevelled egl10 and pleckstrin (DEP) domain and a phosphorylation region. Following agonist-induced platelet stimulation, dimeric p
Autor:
R.L. Summerfield, Kun Zhang, Sean G. Jackson, Murray S. Junop, Xiankun Bao, Richard J. Haslam, Yi Zhang
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 62:324-330
Pleckstrin is an important intracellular protein involved in the phosphoinositide-signalling pathways of platelet activation. This protein contains both N- and C-terminal pleckstrin-homology (PH) domains (N-PH and C-PH). The crystal structure of C-PH
Autor:
Richard J. Haslam
Publikováno v:
Éire-Ireland. 41:215-244
Autor:
Richard J. Haslam
Publikováno v:
Irish Studies Review. 12:303-314
Autor:
Richard J. Haslam
Publikováno v:
Études irlandaises. 29:55-72
This essay explores snobbery as both a mood and a stylistic mode in the poetical, critical, and autobiographical writings of W. B. Yeats. In seeking to answer the question "What kind of snob was Yeats ?" the essay examines three stages of his career
Autor:
Joseph E. Azzam, Elliott K. Jang, Richard J. Haslam, Monica M. L. Davidson, Natalie T. Dickinson
Publikováno v:
British Journal of Haematology. 117:664-675
In studies on human platelets, nitroprusside (NP) alone at 1-10 micromol/l increased platelet cyclic AMP (cAMP) by 40-70%, whereas increases in cyclic GMP (cGMP) were much larger in percentage though not in concentration terms. Collagen enhanced thes
Autor:
Valerie B. O'Donnell, Allison Bloodsworth, Jason P. Eiserich, John C. Giddings, Bruce A. Freeman, Richard J. Haslam, Barbara Coles, Rachel M. McLoughlin, Marcus Jonathan Coffey, Malcolm J. Lewis
Publikováno v:
Journal of Biological Chemistry. 277:5832-5840
Reactive species formed from nitric oxide (NO) nitrate unsaturated fatty acids such as linoleate (LA) to nitrated derivatives including nitrolinoleate (LNO(2)). The effect of LNO(2) on human platelets was examined to define how nitrated lipids might
Publikováno v:
European Journal of Biochemistry. 269:259-271
GTP-binding proteins of the Rab family were cloned from human platelets using RT-PCR. Clones corresponding to two novel Rab proteins, Rab31 and Rab32, and to Rab11A, which had not been detected in platelets previously, were isolated. The coding seque