Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Richard I. Duclos"'
Autor:
Hongying Zheng, Richard I. Duclos, Jr., Conor C. Smith, Harrison W. Farber, Raphael A. Zoeller
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 3, Pp 633-642 (2006)
The synthesis of an ω-pyrene-labeled 1-O-alkyl-sn-glycerol was performed using a chirospecific method starting from R-(−)-2,3-O-isopropylidene-sn-glycerol. The product, 1-O-[9′-(1″-pyrenyl)]nonyl-sn-glycerol (pAG), is a fluorescent ether lipid
Externí odkaz:
https://doaj.org/article/b441b5f8c9c54f02ac5b01f34c5f043e
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 9, Pp 1429-1439 (2002)
Esterification of fatty acids with the small polar molecule carnitine is a required step for the regulated flow of fatty acids into mitochondrial inner matrix. We have studied the interactions of acyl carnitines (ACs) with model membranes [egg yolk p
Externí odkaz:
https://doaj.org/article/3612090e541d46479d430220e00005cb
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 5, Pp 839-849 (1999)
The structural and thermal properties of aqueous dispersions of the totally synthetic cerebrosides, d-erythro-N-palmitoyl galactosyl- and glucosyl-C18-sphingosine (C16:0-GalCer and C16:0-GluCer, respectively) have been studied using differential scan
Externí odkaz:
https://doaj.org/article/bdf9acdf7fa4406791193bf6c18da055
Publikováno v:
Prostaglandins & Other Lipid Mediators. 141:25-33
Introduction Synaptamide, the N-acylethanolamine of docosahexaenoic acid (DHA), is structurally similar to the endocannabinoid N-arachidonoylethanolamine, anandamide. It is an endogenous ligand at the orphan G-protein coupled receptor 110 (GPR110; AD
Publikováno v:
ACS Medicinal Chemistry Letters. 9:274-278
[Image: see text] Tetrahydrolipstatin (THL), its enantiomer, and an additional six diastereomers were evaluated as inhibitors of the hydrolysis of p-nitrophenyl butyrate by porcine pancreatic lipase. IC(50)s were found for all eight stereoisomers ran
Publikováno v:
Chemistry and Physics of Lipids. 210:90-97
N-Docosahexaenoylethanolamine (synaptamide) is structurally similar to the endocannabinoid N-arachidonoylethanolamine (anandamide), but incorporates the omega-3 22:6 fatty acid docosahexaenoic acid (DHA) in place of the omega-6 20:4 fatty acid arachi
Autor:
Srinivas Sridhar, Richard I. Duclos, Samuel J. Gatley, Haotian Wang, Dattatri Nagesha, Rajiv Kumar
Publikováno v:
Nuclear Medicine and Biology. 42:65-70
Introduction Iron-oxide nanoparticles can act as contrast agents in magnetic resonance imaging (MRI), while radiolabeling the same platform with nuclear medicine isotopes allows imaging with positron emission tomography (PET) or single-photon emissio
Publikováno v:
Journal of Sulfur Chemistry. 36:135-144
Selenium is an essential micronutrient in humans due to the important roles of the selenocysteine-containing selenoproteins. Organoselenium metabolites are generally found to be substrates for the biochemical pathways of their sulfur analogs, and the
Autor:
Clinton E. Hagen, S. John Gatley, Timothy R. DeGrado, Mark Jacobson, Kun Qian, Mukesh K. Pandey, Richard I. Duclos
Publikováno v:
ACS Chemical Neuroscience. 5:793-802
N-Acylethanolamines are lipid signaling molecules found throughout the plant and animal kingdoms. The best-known mammalian compound of this class is anandamide, N-arachidonoylethanolamine, one of the endogenous ligands of cannabinoid CB1 and CB2 rece
Publikováno v:
Nuclear medicine and biology. 45
Introduction Anandamide (N-arachidonoylethanolamine) is a retrograde neuromodulator that activates cannabinoid receptors. The concentration of anandamide in the brain is controlled by fatty acid amide hydrolase (FAAH), which has been the focus of rec