Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Richard Howard Green"'
Autor:
Paul F. Lambeth, Fiona S. Lucas, Richard Howard Green, Martin E. Swarbrick, Jeremy John Payne, Lee William Page, Malcolm Clive Carter, Paul John Beswick, Alexander J. Stevens, Sharon C Stratton, Neil Anthony Pegg, John Skidmore, Savvas Kleanthous, Alastair J. Stuart, Sue D. Collins, Sharon Bingham, John Andrew Corfield, Richard Stocker, Joanne O. Wiseman, C. David Hartley, Helen Susanne Price, Neil Mathews, Laura J. Chambers, Iain P. Chessell, Robert Gleave, Nick M. Clayton, Alan Naylor, C. Bountra
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(15)
A novel series of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidine-based cyclooxygenase-2 (COX-2) inhibitors, which have a different arrangement of substituents compared to the more common 1,2-diarylheterocycle based molecules, have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadff8d23a6fefccadd5166b5ed7fd16
https://pubmed.ncbi.nlm.nih.gov/19520573
https://pubmed.ncbi.nlm.nih.gov/19520573
Autor:
Andrew Richard Whittington, Nick M. Clayton, Ian D. Wall, Karamjit S. Jandu, Richard Howard Green, Paul Goldsmith, Brian Peter Slingsby, Anthony D. Rawlings, Gerard Martin Paul Giblin, Andrew J. Brown, Iain P. Chessell, Carl Haslam, William L. Mitchell, Andrew John Eatherton, Alan Naylor, Alex W. Wilson
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(1)
We describe herein the medicinal chemistry approach which led to the discovery of a novel pyridine-3-carboxamide series of CB2 receptor agonists. The SAR of this new template was evaluated and culminated in the identification of analogue 14a which de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522ff0e0e05866d73f5dc7653aba21b2
https://pubmed.ncbi.nlm.nih.gov/19010671
https://pubmed.ncbi.nlm.nih.gov/19010671