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pro vyhledávání: '"Richard Hooijmaijers"'
Autor:
Richard Hooijmaijers, Ridhi Parasrampuria, Eleonora Marostica, Geraldine Ferron‐Brady, Teun M. Post, Sandra A. G. Visser
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 11, Pp 1602-1618 (2023)
Abstract Establishing a dosing regimen that maximizes clinical benefit and minimizes adverse effects for novel therapeutics is a key objective for drug developers. Finding an optimal dose and schedule can be particularly challenging for compounds wit
Externí odkaz:
https://doaj.org/article/96dc123b4b514d36af8c07bddd333909
Autor:
Matthew Fidler, Richard Hooijmaijers, Rik Schoemaker, Justin J. Wilkins, Yuan Xiong, Wenping Wang
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 4, Pp 283-285 (2021)
Externí odkaz:
https://doaj.org/article/4278dcf1b65a4392ae9568d68d944b14
Autor:
Rik Schoemaker, Matthew Fidler, Christian Laveille, Justin J. Wilkins, Richard Hooijmaijers, Teun M. Post, Mirjam N. Trame, Yuan Xiong, Wenping Wang
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 12, Pp 923-930 (2019)
The free and open‐source package nlmixr implements pharmacometric nonlinear mixed effects model parameter estimation in R. It provides a uniform language to define pharmacometric models using ordinary differential equations. Performances of the sto
Externí odkaz:
https://doaj.org/article/2e1c6e4ff2d84c399b05ad5b72e6c0d5
Autor:
Matthew Fidler, Justin J. Wilkins, Richard Hooijmaijers, Teun M. Post, Rik Schoemaker, Mirjam N. Trame, Yuan Xiong, Wenping Wang
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 9, Pp 621-633 (2019)
nlmixr is a free and open‐source R package for fitting nonlinear pharmacokinetic (PK), pharmacodynamic (PD), joint PK‐PD, and quantitative systems pharmacology mixed‐effects models. Currently, nlmixr is capable of fitting both traditional compa
Externí odkaz:
https://doaj.org/article/c685fc663e074a178b95e9516024ef69
Autor:
Justin J. Wilkins, Matthew Fidler, Rik C. Schoemaker, Richard Hooijmaijers, Yuan Xiong, Wenping Wang
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 4, Pp 283-285 (2021)
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
Autor:
Matthew Fidler, Richard Hooijmaijers, Mirjam N. Trame, Justin J. Wilkins, Rik C. Schoemaker, Yuan Xiong, Christian Laveille, Wenping Wang, Teun M. Post
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 12, Pp 923-930 (2019)
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
The free and open-source package nlmixr implements pharmacometric nonlinear mixed effects model parameter estimation in R. It provides a uniform language to define pharmacometric models using ordinary differential equations. Performances of the stoch
Autor:
Richard Hooijmaijers, Justin J. Wilkins, Wenping Wang, Yuan Xiong, Teun M. Post, Rik C. Schoemaker, Matthew Fidler, Mirjam N. Trame
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 9, Pp 621-633 (2019)
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
nlmixr is a free and open-source R package for fitting nonlinear pharmacokinetic (PK), pharmacodynamic (PD), joint PK-PD, and quantitative systems pharmacology mixed-effects models. Currently, nlmixr is capable of fitting both traditional compartment