Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Richard Hoft"'
Autor:
Fawzia Bardag-Gorce, Alissa Diaz, Robert Niihara, Jeremy Stark, Daileen Cortez, Alexander Lee, Richard Hoft, Yutaka Niihara
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 4032 (2022)
Purpose: The purpose of the present study is to investigate the expression of aldehyde dehydrogenases (ALDHs) in rabbit corneas with limbal stem cell deficiency (LSCD) and corneas treated with cultured autologous oral mucosa epithelial cell sheet CAO
Externí odkaz:
https://doaj.org/article/53eff5743267403eb41e8e8e82c3e0db
Autor:
Jeremy Stark, Samuel W. French, Joan Oliva, Andrew Wood, Arjie Florentino, Fawzia Bardag-Gorce, Kumar Tiger, Richard Hoft, Julio Garcia, Andrew Makalinao, Amanda Laporte, Derek Pan, Imara Meepe, Yutaka Niihara, Robert Niihara, Amber M. Gorce, Daileen Cortez
Publikováno v:
The Ocular Surface. 15:749-758
Purpose This study focuses on characterizing proteasomes in corneal epithelial cells (CEC) and in cultured autologous oral mucosal epithelial cell sheets (CAOMECS) used to regenerate the ocular surface. Methods Limbal stem cell deficiency (LSCD) was
Autor:
Joan Oliva, Richard Hoft, Fawzia Bardag-Gorce, Michael Di Lorenzo, Amanda Laporte, Yutaka Niihara, Daileen Cortez, Imara Meepe, Samuel W. French, Jeremy Stark, Andrew Makalinao, Amber M. Gorce, William Lungo
Publikováno v:
Heliyon
Heliyon, Vol 4, Iss 12, Pp e01012-(2018)
Heliyon, Vol 4, Iss 12, Pp e01012-(2018)
Purpose To understand the mechanism of corneal keratin expression and clearance in corneal epithelium with Limbal Stem Cell Deficiency (LSCD). The hypothesis is that LSCD-induced proteasome dysfunction is a contributing factor to keratin aggregation,
Autor:
Joan Oliva, Derek Pan, Andrew Wood, Fawzia Bardag-Gorce, Andrew Makalinao, Samuel W. French, Richard Hoft, Yutaka Niihara, Jacquelyn Thropay
Publikováno v:
The Ocular Surface. 13:150-163
This study investigates the therapeutic effects of carrier-free cultured autologous oral mucosa epithelial cell sheet (CAOMECS) transplantation for experimentally induced severe rabbit limbal stem cell deficiency (LSCD). Buccal biopsies were performe
Autor:
Derek Pan, Joan Oliva, Hope Niihara, Julio Garcia, Samuel W. French, Imara Meepe, Yutaka Niihara, Kumar Tiger, Amanda Laporte, Andrew Makalinao, Richard Hoft, Fawzia Bardag-Gorce, Jacquelyn Thropay, Andrew Wood
Publikováno v:
Journal of Ophthalmology, Vol 2016 (2016)
Journal of Ophthalmology
Journal of Ophthalmology
The role of E-cadherin in epithelial barrier function of cultured autologous oral mucosa epithelial cell sheet (CAOMECS) grafts was examined. CAOMECS were cultured on a temperature-responsive surface and grafted onto rabbit corneas with Limbal Stem C
Autor:
Emil D. Kakkis, Joseph Muenzer, George E. Tiller, Lewis Waber, John Belmont, Merry Passage, Barbara Izykowski, Jeffrey Phillips, Robin Doroshow, Irv Walot, Richard Hoft, Kian Ti Yu, Susie Okazaki, Dave Lewis, Ralph Lachman, Jerry N. Thompson, Elizabeth F. Neufeld
Publikováno v:
New England Journal of Medicine. 344:182-188
Mucopolysaccharidosis I is a lysosomal storage disease caused by a deficiency of the enzyme alpha-L-iduronidase. We evaluated the effect of enzyme-replacement therapy with recombinant human alpha-L-iduronidase in patients with this disorder.We treate
Autor:
Hiroyuki Sota, Derek Pan, Andrew R. Wood, Joan Oliva, Yutaka Niihara, Richard Hoft, Fawzia Bardag-Gorce
Publikováno v:
The FASEB Journal. 27
Autor:
Michael Diament, Monica Sifuentes, Richard Hoft, Kenneth Huff, Susan Okazaki, Emil D. Kakkis, Robin W. Doroshow, Irwin Walot, Gerald F. Cox, G.R. Mason, Stuart J. Swiedler
Publikováno v:
Molecular genetics and metabolism. 90(2)
Recombinant human α-l-iduronidase (Aldurazyme ® , laronidase) was approved as an enzyme replacement therapy for patients with the lysosomal storage disorder, mucopolysaccharidosis I (MPS I). In order to assess the long-term safety and efficacy of l
Autor:
Frank M. Polack, Richard Hoft, Eugene R. Schiff, Saul Ullman, Stephen C. Pflugfelder, Richard K. Forster
Publikováno v:
Cornea. 16:132
PurposeTwo cases of hepatitis B virus (HBV) infection after penetrating keratoplasty are presented.MethodsAn extensive clinical and serologic investigation of these two transplant recipients was performed. In addition, the medical histories, autopsy
Autor:
Richard Hoft, Robert J. Glaser
Publikováno v:
The New England journal of medicine. 307(27)
The growth of prepaid medical-care programs has caused the leaders of a number of academic medical centers to begin to have an increased interest in affiliating with or sponsoring centers in prepaid programs -- otherwise known as health-maintenance o