Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Richard H. Smith"'
Publikováno v:
Infectious Disease Reports, Vol 13, Iss 1, Pp 58-71 (2021)
Contaminated surfaces and indoor environments are important sources of infectious spread within hospital and non-hospital facilities. Bacterial infections such as infections with Clostridioides (formerly Clostridium) difficile (C. difficile) and Stap
Externí odkaz:
https://doaj.org/article/fe18fed0cf534500ad90e6d8e297bf16
Autor:
E. Lynne Kelley, Richard H. Smith, Gillian Corcoran, Sandra Nygren, Mary V. Jacoski, Andrea Fernandes
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 1915-1922 (2021)
Needle-free injection is a desirable goal for many reasons, including reducing pain, anxiety, and eliminating safety risks associated with needle-stick injuries. However, development of a safe, reliable needle-free device optimized for at-home use ha
Externí odkaz:
https://doaj.org/article/ccec6f02949d4d7d8bfde4fe215df9e2
Publikováno v:
Frontiers in Surgery, Vol 6 (2020)
Complete spinal cord injury is a devastating occurrence afflicting millions of people worldwide with no available treatment for functional motor recovery. In this report, we describe a procedure in which we used parts of a device available for chroni
Externí odkaz:
https://doaj.org/article/6f1e6d7bf2534d688324a63e34aa216e
Autor:
Husam Qanash, Yongqin Li, Richard H. Smith, Kaari Linask, Sara Young-Baird, Waleed Hakami, Keyvan Keyvanfar, John S. Choy, Jizhong Zou, Andre Larochelle
Publikováno v:
Cells, Vol 10, Iss 4, p 734 (2021)
Diamond Blackfan Anemia (DBA) is a congenital macrocytic anemia associated with ribosomal protein haploinsufficiency. Ribosomal dysfunction delays globin synthesis, resulting in excess toxic free heme in erythroid progenitors, early differentiation a
Externí odkaz:
https://doaj.org/article/a092e388358d41e1be854e0b2763fc10
Autor:
Richard H. Smith, Yun-Ching Chen, Fayaz Seifuddin, Daniel Hupalo, Camille Alba, Robert Reger, Xin Tian, Daisuke Araki, Clifton L. Dalgard, Richard W. Childs, Mehdi Pirooznia, Andre Larochelle
Publikováno v:
Genes, Vol 11, Iss 12, p 1501 (2020)
CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9)-mediated genome editing holds remarkable promise for the treatment of human genetic diseases. However, the possibility of off-target Cas9 activity rem
Externí odkaz:
https://doaj.org/article/60c5054d8f5d4ebba90f236aa6e1c80e
Autor:
Md Nasimuzzaman, Danielle Lynn, Rebecca Ernst, Michele Beuerlein, Richard H. Smith, Archana Shrestha, Scott Cross, Kevin Link, Carolyn Lutzko, Diana Nordling, David W. Russell, Andre Larochelle, Punam Malik, Johannes C.M. Van der Loo
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Compared to other integrating viral vectors, foamy virus (FV) vectors have distinct advantages as a gene transfer tool, including their nonpathogenicity, the ability to carry larger transgene cassettes, and increased stability of virus particles due
Externí odkaz:
https://doaj.org/article/b6b698cb4bc343e5a99cb5efe3e8967e
Publikováno v:
BioTechniques, Vol 33, Iss 1, Pp 204-211 (2002)
Adeno-associated viruses (AAVs) are replication-defective parvoviruses that require helper virus functions for efficient productive replication. The AAVs are currently premier candidates as vectors for human gene therapy applications. In particular,
Externí odkaz:
https://doaj.org/article/e65940009e90452cb9e221f59791c1dc
Autor:
Richard H. Smith
Few people will easily admit to taking pleasure in the misfortunes of others. But who doesn't enjoy it when an arrogant but untalented contestant is humiliated on American Idol, or when the embarrassing vice of a self-righteous politician is exposed,
Publikováno v:
DETUROPE - The Central European Journal of Tourism and Regional Development. 14:23-44
Autor:
Mehdi Pirooznia, Javier Traba, Stefan Cordes, Ayla Cash, Richard H. Smith, Heather D. Huntsman, Luigi J. Alvarado, Andre Larochelle, Fayaz Seifuddin, Yuesheng Li, Patali S. Cheruku, Daisuke Araki, Jian Fei Fu
Publikováno v:
Stem Cell Reports
Summary Activation of NOTCH signaling in human hematopoietic stem/progenitor cells (HSPCs) by treatment with an engineered Delta-like ligand (DELTA1ext-IgG [DXI]) has enabled ex vivo expansion of short-term HSPCs, but the effect on long-term repopula