Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Richard H. Masland"'
Autor:
Uygar eSümbül, Aleksandar eZlateski, Ashwin eVishwanathan, Richard H. Masland, H. Sebastian eSeung
Publikováno v:
Frontiers in Neuroanatomy, Vol 8 (2014)
The shape and position of a neuron convey information regarding its molecular and functional identity. The identification of cell types from structure, a classic method, relies on the time-consuming step of arbor tracing. However, as genetic tools an
Externí odkaz:
https://doaj.org/article/1c15b2b9410e4a42b34ed5dfde917b77
Publikováno v:
PLoS ONE, Vol 2, Iss 2, p e221 (2007)
The adult mammalian retina is an important model in research on the central nervous system. Many experiments require the combined use of genetic manipulation, imaging, and electrophysiological recording, which make it desirable to use an in vitro pre
Externí odkaz:
https://doaj.org/article/9cdeff6325a8431180250e189833fd1d
Autor:
Cheri Stowell, Claude F. Burgoyne, Ernst R. Tamm, C. Ross Ethier, John E. Dowling, Crawford Downs, Mark H. Ellisman, Steven Fisher, Brad Fortune, Marcus Fruttiger, Tatjana Jakobs, Geoffrey Lewis, Richard H. Masland, Claire H. Mitchell, John Morrison, Sansar C. Sharma, Ian Sigal, Michael Sofroniew, Lin Wang, Janey Wiggs, Samuel Wu
Publikováno v:
Experimental Eye Research. 157:13-19
The biomechanical environment within the optic nerve head (ONH) is complex and is likely directly involved in the loss of retinal ganglion cells (RGCs) in glaucoma. Unfortunately, our understanding of this process is poor. Here we describe factors th
Autor:
Richard T. Libby, Leonard A. Levin, Paul A. Sieving, Alfred Sommer, Robert W. Nickells, Y. Joyce Liao, Larry A. Donoso, Harry A. Quigley, Megan E. Crowe, Richard H. Masland, M Francesca Cordeiro
Publikováno v:
Experimental Eye Research. 157:34-37
Within the field of glaucoma research, neuroprotection is defined as slowing the functional loss in glaucoma by a mechanism independent of lowering of intraocular pressure. There is currently a great potential for research surrounding neuroprotection
Autor:
Ernst R. Tamm, C. Ross Ethier, John E. Dowling, Crawford Downs, Mark H. Ellisman, Steven Fisher, Brad Fortune, Marcus Fruttiger, Tatjana Jakobs, Geoffrey Lewis, Richard H. Masland, Claire H. Mitchell, John Morrison, Sansar C. Sharma, Ian Sigal, Michael Sofroniew, Lin Wang, Janey Wiggs, Samuel Wu
Publikováno v:
Experimental Eye Research. 157:5-12
Autor:
Richard H. Masland
Publikováno v:
Current Biology. 27:R303-R305
The central (foveal) retina takes about 30 milliseconds longer to signal to the brain than the peripheral retina. In the natural world, a 30 millisecond delay could have real consequences. Why did evolution do it this way?
Autor:
Richard H. Masland
Publikováno v:
Neuron. 76(2):266-280
The mammalian retina consists of neurons of >60 distinct types, each playing a specific role in processing visual images. They are arranged in three main stages. The first decomposes the outputs of the rod and cone photoreceptors into ∼12 parallel
Autor:
Richard H. Masland
Publikováno v:
Nature. 542:418-419
A systematic analysis of bipolar cells, which act as a central signalling conduit in the retina, reveals that the neurons' diverse responses to light are generated largely by feedback from neighbouring amacrine cells. See Article p.439
Autor:
Richard H. Masland, Karl Farrow
Publikováno v:
Journal of Neurophysiology. 105:1516-1530
Anatomy predicts that mammalian retinas should have in excess of 12 physiological channels, each encoding a specific aspect of the visual scene. Although several channels have been correlated with morphological cell types, the number of morphological
Publikováno v:
Nature. 451:470-474
To establish functional circuitry, retinal neurons occupy spatial domains by arborizing their processes, which requires the self-avoidance of neurites from an individual cell, and by spacing their cell bodies, which requires positioning the soma and