Platelet proteome reveals features of cell death, antiviral response and viral replication in covid-19

Autor: Monique R. O. Trugilho, Isaclaudia G. Azevedo-Quintanilha, João S. M. Gesto, Emilly Caroline S. Moraes, Samuel C. Mandacaru, Mariana M. Campos, Douglas M. Oliveira, Suelen S. G. Dias, Viviane A. Bastos, Marlon D. M. Santos, Paulo C. Carvalho, Richard H. Valente, Eugenio D. Hottz, Fernando A. Bozza, Thiago Moreno L. Souza, Jonas Perales, Patrícia T. Bozza

Publikováno v: Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)

Abstract Coronavirus disease 2019 (COVID-19) has affected over 400 million people worldwide, leading to 6 million deaths. Among the complex symptomatology of COVID-19, hypercoagulation and thrombosis have been described to directly contribute to leth

Externí odkaz: https://doaj.org/article/872ce91a2be0406f806e073372def0cc

Data on antigen recognition hindrance by antibodies covalently immobilized to Protein G magnetic beads by dimethyl pimelimidate (DMP) cross-linking

Autor: Marcelle A. Caminha, Virginia Maria B. de Lorena, Wilson de Oliveira Júnior, Jonas Perales, Paulo C. Carvalho, Diogo B. Lima, Maria da Glória A.M. Cavalcanti, Sílvia M. Martins, Richard H. Valente, Rubem F.S. Menna-Barreto

Publikováno v: Data in Brief, Vol 22, Iss , Pp 516-521 (2019)

The data presented herein is related to the article entitled ''Trypanosoma cruzi immunoproteome: calpain-like CAP5.5 differentially detected throughout distinct stages of human Chagas disease cardiomyopathy'' [1]. Electrophoretic analyses under denat

Externí odkaz: https://doaj.org/article/7aae552bd66c4cc38d8c4ab2f637ac6a

Proteomics reveals disturbances in the immune response and energy metabolism of monocytes from patients with septic shock

Autor: Giselle Villa Flor Brunoro, Helder I. Nakaya, Monique R.O. Trugilho, Patrícia T. Bozza, Richard H. Valente, Fernando A. Bozza, Pedro Mendes de Azambuja Rodrigues, Mariana Araujo-Pereira

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Sepsis results from a dyshomeostatic response to infection, which may lead to hyper or hypoimmune states. Monocytes are central regulators of the inflammatory response, but our understanding of their role in the genesis and resolution of sepsis is st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940ee140554d23cdfdd9c0feffaf7ffe
https://doaj.org/article/869df548087c49c1885abac0b2e21581

DiagnoMass: A proteomics hub for pinpointing discriminative spectral clusters

Autor: Marlon D.M. Santos, Amanda C. Camillo-Andrade, Diogo B. Lima, Tatiana A.C.B. Souza, Juliana de S. da G. Fischer, Richard H. Valente, Fabio C. Gozzo, Valmir C. Barbosa, Carlos Batthyany, Julia Chamot-Rooke, Rosario Duran, Paulo C. Carvalho

Publikováno v: Journal of Proteomics. 277:104853

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fc67b14dad28d9429e30ae068941718
https://doi.org/10.1016/j.jprot.2023.104853

Glycolytic profile shift and antioxidant triggering in symbiont-free and H2O2-resistant Strigomonas culicis

Autor: Richard H. Valente, Paulo C. Carvalho, Geovane Dias-Lopes, Jonas Perales, Giselle Villa Flor Brunoro, Vítor Ennes-Vidal, Claudia M. d’Avila-Levy, Rubem Figueiredo Sadok Menna-Barreto, Ana Cristina S. Bombaça

Publikováno v: Free Radical Biology and Medicine. 146:392-401

During their life cycle, trypanosomatids are exposed to stress conditions and adapt their energy and antioxidant metabolism to colonize their hosts. Strigomonas culicis is a monoxenous protist found in invertebrates with an endosymbiotic bacterium th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6435bde3d5d3debfef283ac330e68ee0
https://doi.org/10.1016/j.freeradbiomed.2019.11.025