Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Richard H Karas"'
Autor:
Qing Lu, Gavin R Schnitzler, Kazutaka Ueda, Lakshmanan K Iyer, Olga I Diomede, Tiffany Andrade, Richard H Karas
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152807 (2016)
Estrogen promotes the proliferation and migration of vascular endothelial cells (ECs), which likely underlies its ability to accelerate re-endothelialization and reduce adverse remodeling after vascular injury. In previous studies, we have shown that
Externí odkaz:
https://doaj.org/article/0f053d1b8e494e2480ff88bab8ee5122
Autor:
Jin Zhao, Gavin R Schnitzler, Lakshmanan K Iyer, Mark J Aronovitz, Wendy E Baur, Richard H Karas
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156772 (2016)
MicroRNA-offset RNAs (moRs) were first identified in simple chordates and subsequently in mouse and human cells by deep sequencing of short RNAs. MoRs are derived from sequences located immediately adjacent to microRNAs (miRs) in the primary miR (pri
Externí odkaz:
https://doaj.org/article/cb4e36cc342a4bdc8990daecd21f5750
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109416 (2014)
Unique innate immunity-linked γδT cells have been seen in early human artery lesions, but their role in lesion development has received little attention. Here we investigated whether γδT cells modulate atherogenesis in apolipoprotein E-deficient
Externí odkaz:
https://doaj.org/article/26fb4a9896bd49038b740e5363f34701
Autor:
Navin K Kapur, Vikram Paruchuri, Mark J Aronovitz, Xiaoying Qiao, Emily E Mackey, Gerard H Daly, Kishan Ughreja, Jonathan Levine, Robert Blanton, Nicholas S Hill, Richard H Karas
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70802 (2013)
Right ventricular (RV) failure is a major cause of mortality in acute or chronic lung disease and left heart failure. The objective of this study was to demonstrate a percutaneous approach to study biventricular hemodynamics in murine models of prima
Externí odkaz:
https://doaj.org/article/601f03893aa34ae492630ef53ed9ffe1
Autor:
Cristiana Barbati, Marina Pierdominici, Lucrezia Gambardella, Fiorella Malchiodi Albedi, Richard H Karas, Giuseppe Rosano, Walter Malorni, Elena Ortona
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42339 (2012)
In addition to the classical nuclear estrogen receptor, the expression of non-nuclear estrogen receptors localized to the cell surface membrane (mER) has recently been demonstrated. Estrogen and its receptors have been implicated in the development o
Externí odkaz:
https://doaj.org/article/1116b9eefac84cc68177754877404ac4
Autor:
Navin K Kapur, Chetan Shenoy, Adil A Yunis, Najwa N Mohammad, Szuhuei Wilson, Vikram Paruchuri, Emily E Mackey, Xiaoying Qiao, Ameer Shah, Michele L Esposito, Richard H Karas, Iris Z Jaffe
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34344 (2012)
Human studies of therapeutic angiogenesis, stem-cell, and progenitor-cell therapy have failed to demonstrate consistent clinical benefit. Recent studies have shown that heparin increases circulating levels of anti-angiogenic peptides. Given the widel
Externí odkaz:
https://doaj.org/article/97102087fbc64d989c05d5264325a832
Autor:
Timothy D. Calamaras, Suchita Pande, Robert A.U. Baumgartner, Seung Kyum Kim, Joseph C. McCarthy, Gregory L. Martin, Kelly Tam, Angela L. McLaughlin, Guang-rong Wang, Mark J. Aronovitz, Weiyu Lin, Jonathan I. Aguirre, Paulina Baca, Peiwen Liu, Daniel A. Richards, Roger J. Davis, Richard H. Karas, Iris Z. Jaffe, Robert M. Blanton
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
cGMP-dependent protein kinase 1α (PKG1α) promotes left ventricle (LV) compensation after pressure overload. PKG1-activating drugs improve heart failure (HF) outcomes but are limited by vasodilation-induced hypotension. Signaling molecules that medi
Externí odkaz:
https://doaj.org/article/5cb3bfd35e8f4781898dd9135f28a00f
Autor:
Hideyuki Sasaki, Robert M. Blanton, Kazutaka Ueda, Richard H. Karas, Dong Ik Lee, Nazareno Paolocci, Brian O'Rourke, Michael E. Mendelsohn, Masaki Hashimoto, David A. Kass, Guangshuo Zhu, Yuan Yuan, Masayuki Sasaki, Eiki Takimoto, Djahida Bedja, Taro Kariya, Manling Zhang, Matthew Gabrielson, Nina Kaludercic
Publikováno v:
FEBS Lett
Phosphodiesterase 5 inhibition (PDE5i) activates cGMP-dependent protein kinase (PKG) and ameliorates heart failure; however, its impact on cardiac mitochondrial regulation has not been fully determined. Here, we investigated the role of the mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca2e5243ebd6fb35e736a6cfc5be429
https://doi.org/10.1002/1873-3468.14228
https://doi.org/10.1002/1873-3468.14228
Autor:
Mohit Pahuja, William O’Neill, Richard H. Karas, Jeffrey Moses, James Udelson, Haroon Faraz, Navin K. Kapur
Publikováno v:
JACC: Cardiovascular Interventions. 16:S8-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::562543f65c15e839467c7801d6dde74f
https://doi.org/10.1016/j.jcin.2023.01.046
https://doi.org/10.1016/j.jcin.2023.01.046
Autor:
Lara Reyelt, Michael Chin, Paige Crowley, Elric Zweck, Corinne Thomas, Shreyas Bhave, Courtney Boggins, Lija Swain, Xiaoying Qiao, Richard H. Karas, Michele Esposito, William W. O'Neill, Navin K. Kapur
Publikováno v:
Journal of the American College of Cardiology. 76:684-699
Myocardial damage due to acute ST-segment elevation myocardial infarction (STEMI) remains a significant global health problem. New approaches to limit myocardial infarct size and reduce progression to heart failure after STEMI are needed. Mechanicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcadd3281276e11837910ed16942c9b
https://doi.org/10.1016/j.jacc.2020.06.031
https://doi.org/10.1016/j.jacc.2020.06.031