Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Richard H Duerr"'
Autor:
Manuel A Rivas, Brandon E Avila, Jukka Koskela, Hailiang Huang, Christine Stevens, Matti Pirinen, Talin Haritunians, Benjamin M Neale, Mitja Kurki, Andrea Ganna, Daniel Graham, Benjamin Glaser, Inga Peter, Gil Atzmon, Nir Barzilai, Adam P Levine, Elena Schiff, Nikolas Pontikos, Ben Weisburd, Monkol Lek, Konrad J Karczewski, Jonathan Bloom, Eric V Minikel, Britt-Sabina Petersen, Laurent Beaugerie, Philippe Seksik, Jacques Cosnes, Stefan Schreiber, Bernd Bokemeyer, Johannes Bethge, International IBD Genetics Consortium, NIDDK IBD Genetics Consortium, T2D-GENES Consortium, Graham Heap, Tariq Ahmad, Vincent Plagnol, Anthony W Segal, Stephan Targan, Dan Turner, Paivi Saavalainen, Martti Farkkila, Kimmo Kontula, Aarno Palotie, Steven R Brant, Richard H Duerr, Mark S Silverberg, John D Rioux, Rinse K Weersma, Andre Franke, Luke Jostins, Carl A Anderson, Jeffrey C Barrett, Daniel G MacArthur, Chaim Jalas, Harry Sokol, Ramnik J Xavier, Ann Pulver, Judy H Cho, Dermot P B McGovern, Mark J Daly
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008190 (2019)
[This corrects the article DOI: 10.1371/journal.pgen.1007329.].
Externí odkaz:
https://doaj.org/article/3ae352ebf0834370b7f64609330444d8
Autor:
Manuel A Rivas, Brandon E Avila, Jukka Koskela, Hailiang Huang, Christine Stevens, Matti Pirinen, Talin Haritunians, Benjamin M Neale, Mitja Kurki, Andrea Ganna, Daniel Graham, Benjamin Glaser, Inga Peter, Gil Atzmon, Nir Barzilai, Adam P Levine, Elena Schiff, Nikolas Pontikos, Ben Weisburd, Monkol Lek, Konrad J Karczewski, Jonathan Bloom, Eric V Minikel, Britt-Sabina Petersen, Laurent Beaugerie, Philippe Seksik, Jacques Cosnes, Stefan Schreiber, Bernd Bokemeyer, Johannes Bethge, International IBD Genetics Consortium, NIDDK IBD Genetics Consortium, T2D-GENES Consortium, Graham Heap, Tariq Ahmad, Vincent Plagnol, Anthony W Segal, Stephan Targan, Dan Turner, Paivi Saavalainen, Martti Farkkila, Kimmo Kontula, Aarno Palotie, Steven R Brant, Richard H Duerr, Mark S Silverberg, John D Rioux, Rinse K Weersma, Andre Franke, Luke Jostins, Carl A Anderson, Jeffrey C Barrett, Daniel G MacArthur, Chaim Jalas, Harry Sokol, Ramnik J Xavier, Ann Pulver, Judy H Cho, Dermot P B McGovern, Mark J Daly
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007329 (2018)
As part of a broader collaborative network of exome sequencing studies, we developed a jointly called data set of 5,685 Ashkenazi Jewish exomes. We make publicly available a resource of site and allele frequencies, which should serve as a reference f
Externí odkaz:
https://doaj.org/article/36415c854cfc4f458bf1a4f15bcfe6f2
Autor:
Haoran Hu, Xinjun Wang, Site Feng, Zhongli Xu, Jing Liu, Elisa Heidrich-O’Hare, Yanshuo Chen, Molin Yue, Lang Zeng, Ziqi Rong, Tianmeng Chen, Timothy Billiar, Ying Ding, Heng Huang, Richard H. Duerr, Wei Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Droplet-based single-cell sequencing techniques rely on the fundamental assumption that each droplet encapsulates a single cell, enabling individual cell omics profiling. However, the inevitable issue of multiplets, where two or more cells a
Externí odkaz:
https://doaj.org/article/63e8e2ce179744b6a2790a44d9e5f6e8
Autor:
Mélissa Beaudoin, Philippe Goyette, Gabrielle Boucher, Ken Sin Lo, Manuel A Rivas, Christine Stevens, Azadeh Alikashani, Martin Ladouceur, David Ellinghaus, Leif Törkvist, Gautam Goel, Caroline Lagacé, Vito Annese, Alain Bitton, Jakob Begun, Steve R Brant, Francesca Bresso, Judy H Cho, Richard H Duerr, Jonas Halfvarson, Dermot P B McGovern, Graham Radford-Smith, Stefan Schreiber, Philip L Schumm, Yashoda Sharma, Mark S Silverberg, Rinse K Weersma, Quebec IBD Genetics Consortium, NIDDK IBD Genetics Consortium, International IBD Genetics Consortium, Mauro D'Amato, Severine Vermeire, Andre Franke, Guillaume Lettre, Ramnik J Xavier, Mark J Daly, John D Rioux
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003723 (2013)
Genome-wide association studies and follow-up meta-analyses in Crohn's disease (CD) and ulcerative colitis (UC) have recently identified 163 disease-associated loci that meet genome-wide significance for these two inflammatory bowel diseases (IBD). T
Externí odkaz:
https://doaj.org/article/33fe8a7a38e3471896ec4843eff4a498
Autor:
Jürgen Glas, Julia Seiderer, Darina Czamara, Giulia Pasciuto, Julia Diegelmann, Martin Wetzke, Torsten Olszak, Christiane Wolf, Bertram Müller-Myhsok, Tobias Balschun, Jean-Paul Achkar, M Ilyas Kamboh, Andre Franke, Richard H Duerr, Stephan Brand
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52873 (2012)
Genome-wide association studies identified a PTGER4 expression-modulating region on chromosome 5p13.1 as Crohn's disease (CD) susceptibility region. The study aim was to test this association in a large cohort of patients with inflammatory bowel dise
Externí odkaz:
https://doaj.org/article/fd698a4c82b847e4b355979e8cb7896b
Autor:
Eimear E Kenny, Itsik Pe'er, Amir Karban, Laurie Ozelius, Adele A Mitchell, Sok Meng Ng, Monica Erazo, Harry Ostrer, Clara Abraham, Maria T Abreu, Gil Atzmon, Nir Barzilai, Steven R Brant, Susan Bressman, Edward R Burns, Yehuda Chowers, Lorraine N Clark, Ariel Darvasi, Dana Doheny, Richard H Duerr, Rami Eliakim, Nir Giladi, Peter K Gregersen, Hakon Hakonarson, Michelle R Jones, Karen Marder, Dermot P B McGovern, Jennifer Mulle, Avi Orr-Urtreger, Deborah D Proctor, Ann Pulver, Jerome I Rotter, Mark S Silverberg, Thomas Ullman, Stephen T Warren, Matti Waterman, Wei Zhang, Aviv Bergman, Lloyd Mayer, Seymour Katz, Robert J Desnick, Judy H Cho, Inga Peter
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002559 (2012)
Crohn's disease (CD) is a complex disorder resulting from the interaction of intestinal microbiota with the host immune system in genetically susceptible individuals. The largest meta-analysis of genome-wide association to date identified 71 CD-susce
Externí odkaz:
https://doaj.org/article/abe8a066ac7148858f2fdce06d10c5d5
Autor:
Brindusa Truta, Ferdouse Begum, Lisa Wu Datta, Steven R. Brant, Judy H. Cho, Richard H. Duerr, Dermot B.P. McGovern, John R. Rioux, Mark S. Silverberg
Publikováno v:
Gastro Hep Advances. 2:22-32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa5671e63a7cbba961a9d61c30836610
https://doi.org/10.1016/j.gastha.2022.08.001
https://doi.org/10.1016/j.gastha.2022.08.001
Autor:
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, Cigdem Sevim Bayrak, Peng Zhang, Aayushee Jain, Patrick Maffucci, Ksenija Sabic, Tielman Van Vleck, Girish Nadkarni, Lee A. Denson, Harry Ostrer, Adam P. Levine, Elena R. Schiff, Anthony W. Segal, Subra Kugathasan, Peter D. Stenson, David N. Cooper, L. Philip Schumm, Scott Snapper, Mark J. Daly, Talin Haritunians, Richard H. Duerr, Mark S. Silverberg, John D. Rioux, Steven R. Brant, Dermot P. B. McGovern, Judy H. Cho, Yuval Itan
Publikováno v:
Nature Communications. 14
Inflammatory bowel disease (IBD) is a group of chronic digestive tract inflammatory conditions whose genetic etiology is still poorly understood. The incidence of IBD is particularly high among Ashkenazi Jews. Here, we identify 8 novel and plausible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af42b7dbc79ae2f023af0c8ecfd76885
https://doi.org/10.1038/s41467-023-37849-3
https://doi.org/10.1038/s41467-023-37849-3
Autor:
Andres Yarur, Freddy Caldera, Sirimon O'Charoen, Joshua R. Korzenik, Cecile Norris, Matthew Bohm, Monika Fischer, Sara Sweeney, Alandra Weaver, Uni Wong, Sushila Dalal, Themistocles Dassopoulos, Katerina Wells, David Hudesman, Lilani P. Perera, Shrinivas Bishu, Caren Heller, Richard H. Duerr, Tara Fehlmann, Deepak Parakkal, Raymond K. Cross, James D. Lewis, Manreet Kaur, Matthew A. Ciorba, Sumona Saha, Elizabeth A. Scoville, Laura E. Raffals, Joel Pekow, Scott B. Snapper, Angela Dobes, Meenakshi Bewtra
Publikováno v:
Inflamm Bowel Dis
Background Clinical and molecular subcategories of inflammatory bowel disease (IBD) are needed to discover mechanisms of disease and predictors of response and disease relapse. We aimed to develop a study of a prospective adult research cohort with I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdddd093b9db869b8411122566803360
https://doi.org/10.1093/ibd/izab071
https://doi.org/10.1093/ibd/izab071
Autor:
Xinjun Wang, Zhongli Xu, Haoran Hu, Xueping Zhou, Yanfu Zhang, Robert Lafyatis, Kong Chen, Heng Huang, Ying Ding, Richard H Duerr, Wei Chen
Publikováno v:
PNAS Nexus. 1
The recent advance of single cell sequencing (scRNA-seq) technology such as Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq) allows researchers to quantify cell surface protein abundance and RNA expression simultaneously at s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4b438badb4240e2895ac83face681c
https://doi.org/10.1093/pnasnexus/pgac165
https://doi.org/10.1093/pnasnexus/pgac165