Výsledky vyhledávání - "Richard H, Guy"

Akademický článek

Reverse Iontophoretic Extraction of Skin Cancer-Related Biomarkers

Autor: Maxim Morin, Sebastian Björklund, Skaidre Jankovskaja, Kieran Moore, Maria Begoña Delgado-Charro, Tautgirdas Ruzgas, Richard H. Guy, Johan Engblom

Publikováno v: Pharmaceutics, Vol 14, Iss 1, p 79 (2021)

Non-invasive methods for early diagnosis of skin cancer are highly valued. One possible approach is to monitor relevant biomarkers such as tryptophan (Trp) and kynurenine (Kyn), on the skin surface. The primary aim of this in vitro investigation was,

Externí odkaz: https://doaj.org/article/2be359d4657d464484a1d81451dd9a53

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Raman Spectroscopic Tools to Probe the Skin–(Trans)dermal Formulation Interface

Autor: Hazel Garvie-Cook, Magdalena Hoppel, Richard H. Guy

Publikováno v: Molecular Pharmaceutics. 19:4010-4016

Medicines designed to deliver the active pharmaceutical ingredient either into or through the skin─often referred to as topicals and transdermals, respectively─are generally considered to be complex drug products. A particular challenge faced by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c9b7dbe656a28bd07040ccb8628b46
https://doi.org/10.1021/acs.molpharmaceut.2c00480

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Non‐destructive, reverse iontophoretic extraction of phytochemicals from Mangifera indica , Centella asiatica , Punica granatum , and Citrus sinensis

Autor: Joan Eilstein, Vimal Nair, Kieran Moore, Steve Thomas Pannakal, Sébastien Grégoire, Prashant Ekhar, Richard H. Guy, M. Begoña Delgado‐Charro, Nita Roy

Publikováno v: Phytochemical Analysis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c2cf4f352133a0bac0edc338c31f0be
https://doi.org/10.1002/pca.3219

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Influence of incorrect staging of colorectal carcinoma on oncological outcome: are we playing safely?

Autor: Chris Cunningham, Bruce George, Claudia Reali, Richard H. Guy, Stephen A. Boyce, Ian Lindsey, Oliver Jones, Gabriele Bocca

Publikováno v: Updates in Surgery. 74:591-597

Accurate preoperative staging of colorectal cancers is critical in selecting patients for neoadjuvant therapy prior to resection. Inaccurate staging, particularly understaging, may lead to involved resection margins and poor oncological outcomes. Our

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceefe217f4f07c17c089ea238246c463
https://doi.org/10.1007/s13304-021-01095-3

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Regulatory Science and Innovation Programme for Europe (ReScIPE)

Autor: Richard H. Guy, Angela Brand, Philip A. Hines, Marisa Papaluca-Amati, Anthony J. Humphreys

Publikováno v: Hines, P A, Guy, R H, Brand, A, Humphreys, A J & Papaluca-Amati, M 2020, ' Regulatory Science and Innovation Programme for Europe (ReScIPE) : A proposed model ', British Journal Of Clinical Pharmacology, vol. 86, no. 2, pp. 2530-2534 . https://doi.org/10.1111/bcp.14099
British Journal of Clinical Pharmacology, 86(12), 2530-2534. Wiley

Regulatory science underpins the objective evaluation of medicinal products. It is therefore imperative that regulatory science and expertise remain at the cutting edge so that innovations of ever-increasing complexity are translated safely and swift

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f8a79c6fdf5f774e1518941497c2c6
https://doi.org/10.1111/bcp.14099

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Predicting topical drug clearance from the skin

Autor: Annette L. Bunge, M. Begoña Delgado-Charro, Richard H. Guy, Magdalena Hoppel, Maria Alice Maciel Tabosa

Publikováno v: Drug Delivery and Translational Research

For topical drug products that target sites of action in the viable epidermal and/or upper dermal compartment of the skin, the local concentration profiles have proven difficult to quantify because drug clearance from the viable cutaneous tissue is n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb2747d9a5a56d054505e960de1d3ea
https://doi.org/10.1007/s13346-020-00864-8

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