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pro vyhledávání: '"Richard Gundersdorf"'
Publikováno v:
Analytica Chimica Acta. 1125:279-287
Peptides have become a fast-growing segment of the pharmaceutical industry over the past few decades. It is essential to develop cutting edge analytical techniques to support the discovery and development of peptide therapeutics, especially to examin
Autor:
Philip Jones, Laura S. Lubbers, Blake A. Rowe, Fred Hess, Susan E. Browne, Ian J. Reynolds, Lisa M. Hodge, Richard Gundersdorf
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 61:319-328
Poly ADP-ribose polymerase (PARP) maintains genomic integrity by repairing DNA strand breaks, however over-activation of PARP following neural tissue injury is hypothesized to cause neuronal death. Therefore, PARP inhibitors have potential for limiti
Publikováno v:
Rapid Communications in Mass Spectrometry. 17:2413-2422
A hybrid linear ion trap/triple quadrupole mass spectrometer was used to demonstrate the value of collecting full scan qualitative data during quantitative analysis of target compounds. We present examples of the additional information that can be ob