Zobrazeno 1 - 10
of 558
pro vyhledávání: '"Richard Goddard"'
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 79, Iss 12, Pp 1194-1198 (2023)
The title compound, C15H15F3N2O3S, crystallizes in the monoclinic system, space group I2/a, with Z = 8. As expected, the nine-membered heterobicyclic system is virtually planar and the cyclohexyl group adopts a chair conformation. There is structural
Externí odkaz:
https://doaj.org/article/6158fe0e49f6401e957ae0b343676661
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1795 (2024)
4-(4-nitrophenyl)thiomorpholine, the title compound, has been used as a precursor for the corresponding 4-thiomorpholinoaniline, which is a useful building block in medicinal chemistry. The crystal and molecular structures of the title compound, howe
Externí odkaz:
https://doaj.org/article/494cfc975dc34af2ab40cf9e7827c266
Autor:
Paul R. Palme, Richard Goddard, Markus Leutzsch, Adrian Richter, Peter Imming, Rüdiger W. Seidel
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1737 (2023)
Betaines of squaric acid have gained research interest because of their structural and spectral properties. We elucidated the crystal and molecular structure of the triethylammonium betaine of squaric acid (1) by X-ray crystallography, IR, and NMR sp
Externí odkaz:
https://doaj.org/article/8bf0b5f28b364669934109a92915eb7f
Publikováno v:
Molbank, Vol 2023, Iss 2, p M1647 (2023)
Trehalose conjugates of 3-hydroxychromone (3HC) dyes have previously been utilized as fluorescence labels to detect metabolically active mycobacteria with a view to facilitating point-of-care detection of mycobacterial pathogens, especially Mycobacte
Externí odkaz:
https://doaj.org/article/3b5cb7b34c0d4deabfbac87f1648e824
Publikováno v:
IUCrData, Vol 8, Iss 1, p x230025 (2023)
The title compound, C16H16N4O3, was obtained as a side product during the synthesis of the previously reported antitubercular agent N-(2-fluoroethyl)-1-[(6-methoxy-5-methylpyrimidin-4-yl)methyl]-1H-benzo[d]imidazole-4-carboxamide and structurally cha
Externí odkaz:
https://doaj.org/article/38ccbf2ef57a408c8e633c85e6244c2b
Publikováno v:
Chemistry, Vol 3, Iss 2, Pp 578-584 (2021)
Knowledge about the absolute configuration of small bioactive organic molecules is essential in pharmaceutical research because enantiomers can exhibit considerably different effects on living organisms. X-ray crystallography enables chemists to dete
Externí odkaz:
https://doaj.org/article/30ffc3a7156141178553159b05d650ed
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 77, Iss 2, Pp 142-147 (2021)
8-Nitro-1,3-benzothiazin-4-ones are a promising class of new antitubercular agents, two candidates of which, namely BTZ043 and PBTZ169 (INN: macozinone), have reached clinical trials. The crystal and molecular structures of two synthetic precursors,
Externí odkaz:
https://doaj.org/article/ada1f76b39f74ef496c042a3cd572cb5
Autor:
Tamira Eckhardt, Richard Goddard, Ines Rudolph, Adrian Richter, Christoph Lehmann, Peter Imming, Rüdiger W. Seidel
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 9, Pp 1442-1446 (2020)
1,3-Benzothiazin-4-ones (BTZs) are a promising new class of anti-tuberculosis drug candidates, some of which have reached clinical trials. The title compound, the benzamide derivative [2-chloro-3-nitro-5-(trifluoromethyl)phenyl](piperidin-1-yl)methan
Externí odkaz:
https://doaj.org/article/311bf964d435432fa7007213502a9115
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 8, Pp 1255-1259 (2020)
The synthesis of ethyl 2-[(4-methylpyridin-2-yl)amino)-4-(pyridin-2-yl)thiazole- 5-carboxylate via the Hantzsch reaction and partial in situ transesterification during recrystallization from methanol-d4 to the d3-methyl ester, resulting in the title
Externí odkaz:
https://doaj.org/article/55a0cf0e6ca3427a9033fea18ea2aad0
Publikováno v:
IUCrData, Vol 1, Iss 11, p x161735 (2016)
The crystal structure of the organic–inorganic title salt, [Mn(C18H18N2O4)(H2O)2]ClO4, has been redetermined at 100 K. In contrast to the crystal structure determinations at room temperature [Akitsu et al. (2005). Acta Cryst. C61, m324–m328; Berm
Externí odkaz:
https://doaj.org/article/0f905b3bcfd9419ca2acaffb78714136