Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Richard Gale"'
Publikováno v:
Ophthalmology and Therapy, Vol 13, Iss 8, Pp 2063-2066 (2024)
Abstract This is a summary of the original article ‟Cost‑Effectiveness of Faricimab in the Treatment of Diabetic Macular Oedema (DMO): A UK Analysis”. DMO, a serious eye condition that can lead to vision loss in people with diabetes, is a signi
Externí odkaz:
https://doaj.org/article/03c2c0b0de9f45fd8c4175f89e79f956
Autor:
Usha Chakravarthy, Tunde Peto, Sobha Sivaprasad, Luke Vale, Alastair K Denniston, Nadia K Waheed, Praveen J Patel, Konstantinos Balaskas, Richard Gale, Yemisi Takwoingi, Gabriella de Salvo, Ridhi Agarwal, William McKinnon, Ashleigh Kernohan, Evangelos Minos, Savita Madhusudhan, Magdalena Niestrata, Adam R Khan, Paulo Barbeiro
Publikováno v:
BMJ Open, Vol 14, Iss 5 (2024)
Introduction The diagnosis of neovascular age-related macular degeneration (nAMD), the leading cause of visual impairment in the developed world, relies on the interpretation of various imaging tests of the retina. These include invasive angiographic
Externí odkaz:
https://doaj.org/article/24b7e37057c743fdab035f9714a27bc8
Autor:
Louise Downey, Richard Gale, Philip Severn, Vina Manjunath, Rajarshi Mukherjee, Helen Devonport, Maged Habib
Publikováno v:
BMJ Open Ophthalmology, Vol 6, Iss 1 (2021)
First-line treatment of centrally involved diabetic macular oedema (CI-DMO) is often with an anti-vascular endothelial growth factor (anti-VEGF) agent. Although this can provide efficacy in the majority of eyes, a sizeable proportion do not respond s
Externí odkaz:
https://doaj.org/article/a7c8fdec743841b98cbabced0838a175
Autor:
Michael Crompton, Tom Purnell, Hayley E Tyrer, Andrew Parker, Greg Ball, Rachel E Hardisty-Hughes, Richard Gale, Debbie Williams, Charlotte H Dean, Michelle M Simon, Ann-Marie Mallon, Sara Wells, Mahmood F Bhutta, Martin J Burton, Hilda Tateossian, Steve D M Brown
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006969 (2017)
Otitis media (OM), inflammation of the middle ear (ME), is a common cause of conductive hearing impairment. Despite the importance of the disease, the aetiology of chronic and recurrent forms of middle ear inflammatory disease remains poorly understo
Externí odkaz:
https://doaj.org/article/4037f860bf2443118801ffd0087a7524
Autor:
Ivan Rattray, Edward J Smith, William R Crum, Thomas A Walker, Richard Gale, Gillian P Bates, Michel Modo
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0168556 (2017)
A variety of mouse models have been developed that express mutant huntingtin (mHTT) leading to aggregates and inclusions that model the molecular pathology observed in Huntington's disease. Here we show that although homozygous HdhQ150 knock-in mice
Externí odkaz:
https://doaj.org/article/02a1eb9f87a24ff0bf3fe0e6e3785ecf
Autor:
Ivan Rattray, Edward J Smith, William R Crum, Thomas A Walker, Richard Gale, Gillian P Bates, Michel Modo
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84726 (2013)
Huntington's disease (HD) is caused by the expansion of a CAG repeat in the huntingtin (HTT) gene. The R6 mouse models of HD express a mutant version of exon 1 HTT and typically develop motor and cognitive impairments, a widespread huntingtin (HTT) a
Externí odkaz:
https://doaj.org/article/9aef2a1430684f44b41840a660bd8f54
Autor:
Richard Gale
Publikováno v:
International Journal for the Scholarship of Teaching and Learning, Vol 3, Iss 2 (2009)
Excerpt: When I first became involved formally in scholarship of teaching and learning, it was the result of frustration and surprise tempered by high expectations and hope. I was teaching in a school of liberal studies that used program portfolios a
Externí odkaz:
https://doaj.org/article/ae782220e431419e868d44311bd7c250
Publikováno v:
IEEE Sensors Journal. 23:5437-5447
Autor:
Michal Chorev, Jonas Haderlein, Shruti Chandra, Geeta Menon, Benjamin Burton, Ian Pearce, Martin McKibbin, Sridevi Thottarath, Eleni Karatsai, Swati Chandak, Ajay Kotagiri, James Talks, Anna Grabowska, Faruque Ghanchi, Richard Gale, Robin Hamilton, Bhavna Antony, Rahil Garnavi, Iven Mareels, Andrea Giani, Victor Chong, Sobha Sivaprasad
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 8; Pages: 3013
Patients diagnosed with exudative neovascular age-related macular degeneration are commonly treated with anti-vascular endothelial growth factor (anti-VEGF) agents. However, response to treatment is heterogeneous, without a clinical explanation. Pred
Autor:
Ian Pearce, Winfried Amoaku, Clare Bailey, Louise Downey, Richard Gale, Faruque Ghanchi, Robin Hamilton, Sajjad Mahmood, Geeta Menon, Jenny Nosek, James Talks, Yit Yang
Publikováno v:
Eye. 36:1725-1734
Untreated neovascular age-related macular degeneration (nAMD) can lead to severe and permanent visual impairment. The chronic nature of the disease can have a significant impact on patients' quality of life and an economic and time burden on medical