Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Richard G. DiScipio"'
Autor:
Atul Agarwal, John P. Atkinson, Paul N. Barlow, Scott R. Barnum, Saverio Bettuzzi, Anna M. Blom, Susan A. Boackle, Suzanne Bohlson, Daniel C. Bullard, David M. Cauvi, Maciej Cedzyński, Joseph M. Christy, Liam G. Coulthard, Richard G. DiScipio, Christian Drouet, Viviana P. Ferreira, Zvi Fishelson, Christine Gaboriaud, Arije Ghannam, Berhane Ghebrehiwet, Ionita Ghiran, Owen A. Hawksworth, Mingjun Huang, David E. Isenman, Jens C. Jensenius, Claudia Kemper, David C. Kilpatrick, Jennifer Laskowski, M. Kathryn Liszewski, Kartik Manne, Misao Matsushita, Paul Morgan, Valeria Naponelli, Sthanam V.L. Narayana, Anne Nicholson-Weller, Katsuki Ohtani, Marcin Okrój, Luz D. Orozco, Michael K. Pangburn, Ramus Pihl, Steven D. Podos, Kenneth M. Pollard, Denise Ponard, Kristian Riesbeck, Véronique Rossi, Theresa N. Schein, Yu-Ching Su, Anna S. Świerzko, Nicole M. Thielens, Steffen Thiel, Joshua M. Thurman, Christopher B. Toomey, Menno van Lookeren Campagne, Nobutaka Wakamiya, Rick A. Wetsel, Trent M. Woodruff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88adbc54a7335bbb530f21b568a13a3e
https://doi.org/10.1016/b978-0-12-810420-0.01002-6
https://doi.org/10.1016/b978-0-12-810420-0.01002-6
Autor:
Richard G. DiScipio
Component C6 is a single-chain plasma glycoprotein of Mr ∼ 108,000 that participates in the last phase of complement activation, namely the formation of the membrane attack complex. This macromolecular assembly consists of C5b through C9 and is a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a52805e0622bef3adf8425166e16a03c
https://doi.org/10.1016/b978-0-12-810420-0.00019-5
https://doi.org/10.1016/b978-0-12-810420-0.00019-5
Publikováno v:
Journal of immunological methods. 450
Two novel magnetic agarose bead based assays have been developed to measure complement component C5 interaction with C3b and the Factor I Modules (FIMs) of C7. One innovation was to couple C3b onto the magnetic agarose bead using the alternative path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd6b8d8f3ab7cf31b1a4ec43aafd578
https://pubmed.ncbi.nlm.nih.gov/28757372
https://pubmed.ncbi.nlm.nih.gov/28757372
Publikováno v:
Journal of Biomedical Science and Engineering. :1-13
A major portion of the beneficial effect of mesenchymal stem cells (MSC) is due to the production of trophic and angiogenic factors by these cells, and one of the efforts to improve the therapeutic efficacy of these cells lies in enhancing this capac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf9da47eed798589d00bae401ecadb90
https://doi.org/10.4236/jbise.2013.68a1001
https://doi.org/10.4236/jbise.2013.68a1001
Autor:
Pietro Roversi, Gregers R. Andersen, Lars Sottrup-Jensen, Lasse Jenner, Cristiano L. P. Oliveira, Richard G. DiScipio, Susan M. Lea, Jan Skov Pedersen, Miles A. Nunn, Nick S. Laursen, Folmer Fredslund
Publikováno v:
Fredslund, F, Laursen, N S, Roversi, P, Jenner, L B, Oliveira, C L P, Pedersen, J S, Nunn, M A, Lea, S M, Discipio, R, Sottrup-Jensen, L & Andersen, G R 2008, ' Structure of and influence of a tick complement inhibitor on human complement component 5 ', Nature Immunology, vol. 9, no. 7, pp. 753-60 . https://doi.org/10.1038/ni.1625
To provide insight into the structural and functional properties of human complement component 5 (C5), we determined its crystal structure at a resolution of 3.1 A. The core of C5 adopted a structure resembling that of C3, with the domain arrangement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c0c74ff717eb548d7fe1baad58b3ca
https://doi.org/10.1038/ni.1625
https://doi.org/10.1038/ni.1625
Publikováno v:
Immunology. 135:287-298
The observation that human monocytes cultured in the presence of the chemokine CCL18 showed increased survival, led us to profile cytokine expression in CCL18-stimulated versus control cultures. CCL18 caused significantly increased expression of chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab2a25b174643315791bc14ce0ab77ad
https://doi.org/10.1111/j.1365-2567.2011.03541.x
https://doi.org/10.1111/j.1365-2567.2011.03541.x
Autor:
Robert C. Liddington, Richard G. DiScipio, Boguslaw Stec, Laurie A. Bankston, Alexander E. Aleshin, Ingrid U. Schraufstatter
Publikováno v:
Journal of Biological Chemistry. 287:10210-10222
The complement membrane attack complex (MAC) is formed by the sequential assembly of C5b with four homologous proteins as follows: one copy each of C6, C7, and C8 and 12-14 copies of C9. Together these form a lytic pore in bacterial membranes. C6 thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a0e5ffebecf38b3de3f568c1bacc02
https://doi.org/10.1074/jbc.m111.327809
https://doi.org/10.1074/jbc.m111.327809
Publikováno v:
International Immunopharmacology. 7:1909-1923
Eosinophils are blood and tissue immune cells that participate in a diverse range of activities normally beneficial for the host defense, but in circumstances of untoward inflammatory conditions these cells can be responsible for pathological respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f65752d610e9f0467d1dc10884ccb4
https://doi.org/10.1016/j.intimp.2007.07.006
https://doi.org/10.1016/j.intimp.2007.07.006
Publikováno v:
Breast Cancer Research and Treatment. 110:211-222
The chemokine receptor CXCR4 is functionally expressed on the cell surface of various cancer cells, and plays a role in cell proliferation and migration of these cells. Specifically, in breast cancer cells the CXCR4/CXCL12 axis has been implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0950eb33be874c5c013f199a46c55c94
https://doi.org/10.1007/s10549-007-9712-7
https://doi.org/10.1007/s10549-007-9712-7
Publikováno v:
Protein expression and purification. 121
A method is reported to purify Fibulin-1 from human plasma resulting in a 36% recovery. The steps involve removal of the cryoglobulin and the vitamin K dependent proteins followed by polyethylene glycol and ammonium sulfate precipitations, DEAE-Sepha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f24f6cd577bf8ed234b92b9dfc761c
https://pubmed.ncbi.nlm.nih.gov/26826315
https://pubmed.ncbi.nlm.nih.gov/26826315