Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Richard G Jenner"'
Autor:
Hayley Porter, Yang Li, Maria Victoria Neguembor, Manuel Beltran, Wazeer Varsally, Laura Martin, Manuel Tavares Cornejo, Dubravka Pezić, Amandeep Bhamra, Silvia Surinova, Richard G Jenner, Maria Pia Cosma, Suzana Hadjur
Publikováno v:
eLife, Vol 12 (2023)
Most studies of cohesin function consider the Stromalin Antigen (STAG/SA) proteins as core complex members given their ubiquitous interaction with the cohesin ring. Here, we provide functional data to support the notion that the SA subunit is not a m
Externí odkaz:
https://doaj.org/article/c75b957f25434498af13a92ce3fcf355
Autor:
Katrina Soderquest, Arnulf Hertweck, Claudia Giambartolomei, Stephen Henderson, Rami Mohamed, Rimma Goldberg, Esperanza Perucha, Lude Franke, Javier Herrero, Vincent Plagnol, Richard G Jenner, Graham M Lord
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006587 (2017)
The polarization of CD4+ T cells into distinct T helper cell lineages is essential for protective immunity against infection, but aberrant T cell polarization can cause autoimmunity. The transcription factor T-bet (TBX21) specifies the Th1 lineage an
Externí odkaz:
https://doaj.org/article/1b047c1f9aaf46738e2b7b4684f706e9
Autor:
Michael J McClellan, C David Wood, Opeoluwa Ojeniyi, Tim J Cooper, Aditi Kanhere, Aaron Arvey, Helen M Webb, Richard D Palermo, Marie L Harth-Hertle, Bettina Kempkes, Richard G Jenner, Michelle J West
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003636 (2013)
Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is perturbed principally through the actions of EBV EBNA 2, 3A, 3B and 3C, with cellular genes dereg
Externí odkaz:
https://doaj.org/article/f1ec0ab7ce444d78be87a77e27947c93
Autor:
Torsten Schaller, Karen E Ocwieja, Jane Rasaiyaah, Amanda J Price, Troy L Brady, Shoshannah L Roth, Stéphane Hué, Adam J Fletcher, KyeongEun Lee, Vineet N KewalRamani, Mahdad Noursadeghi, Richard G Jenner, Leo C James, Frederic D Bushman, Greg J Towers
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002439 (2011)
Lentiviruses such as HIV-1 traverse nuclear pore complexes (NPC) and infect terminally differentiated non-dividing cells, but how they do this is unclear. The cytoplasmic NPC protein Nup358/RanBP2 was identified as an HIV-1 co-factor in previous stud
Externí odkaz:
https://doaj.org/article/a5b5dc81b6be4ecc85627141155f796e
Autor:
Jan-Hendrik Schroeder, Gordon Beattie, Jonathan W. Lo, Tomasz Zabinski, Nick Powell, Joana F. Neves, Richard G. Jenner, Graham M. Lord
Publikováno v:
Frontiers in Immunology. 14
Huge progress has been made in understanding the biology of innate lymphoid cells (ILC) by adopting several well-known concepts in T cell biology. As such, flow cytometry gating strategies and markers, such as CD90, have been applied to indentify ILC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68ae8b5ee0480b12c91834eea0c636dd
https://doi.org/10.3389/fimmu.2023.1113735
https://doi.org/10.3389/fimmu.2023.1113735
Autor:
Adrienne M. Flanagan, Udo Oppermann, Richard G. Jenner, Nischalan Pillay, Paul E. Brennan, Catrine Johansson, Tamas Szommer, Edward S. Hookway, Patrick Lombard, Anthony Tumber, Martin Philpott, Lorena Ligammari, Graham Wells, Garima Khandelwal, Adam P. Cribbs, Lucia Cottone
Chordoma RNAseq_all cell lines_gene lists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6578577fc25599f576ad85a99627634
https://doi.org/10.1158/0008-5472.22426561
https://doi.org/10.1158/0008-5472.22426561
Autor:
Adrienne M. Flanagan, Udo Oppermann, Richard G. Jenner, Nischalan Pillay, Paul E. Brennan, Catrine Johansson, Tamas Szommer, Edward S. Hookway, Patrick Lombard, Anthony Tumber, Martin Philpott, Lorena Ligammari, Graham Wells, Garima Khandelwal, Adam P. Cribbs, Lucia Cottone
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c485bbf1b953bd1304c5c3572926d52
https://doi.org/10.1158/0008-5472.22426555.v1
https://doi.org/10.1158/0008-5472.22426555.v1
Autor:
Adrienne M. Flanagan, Udo Oppermann, Richard G. Jenner, Nischalan Pillay, Paul E. Brennan, Catrine Johansson, Tamas Szommer, Edward S. Hookway, Patrick Lombard, Anthony Tumber, Martin Philpott, Lorena Ligammari, Graham Wells, Garima Khandelwal, Adam P. Cribbs, Lucia Cottone
Expression of the transcription factor brachyury (TBXT) is normally restricted to the embryo, and its silencing is epigenetically regulated. TBXT promotes mesenchymal transition in a subset of common carcinomas, and in chordoma, a rare cancer showing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8212a639932c9ee33a88afa370634f22
https://doi.org/10.1158/0008-5472.c.6512377
https://doi.org/10.1158/0008-5472.c.6512377
Autor:
Arnulf Hertweck, Maria Vila de Mucha, Paul R Barber, Robert Dagil, Hayley Porter, Andres Ramos, Graham M Lord, Richard G Jenner
Publikováno v:
Nucleic acids research. 50(8)
Lineage-determining transcription factors (LD-TFs) drive the differentiation of progenitor cells into a specific lineage. In CD4+ T cells, T-bet dictates differentiation of the TH1 lineage, whereas GATA3 drives differentiation of the alternative TH2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b633321c197d866d7b2e7f342ba1569
https://pubmed.ncbi.nlm.nih.gov/35438764
https://pubmed.ncbi.nlm.nih.gov/35438764
Autor:
Nischalan Pillay, Adrienne M. Flanagan, Lorena Ligammari, Udo Oppermann, Paul Brennan, T. Szommer, Lucia Cottone, Graham Wells, Catrine Johansson, Patrick Lombard, Martin Philpott, E S Hookway, Garima Khandelwal, Adam P. Cribbs, Richard G. Jenner, Anthony Tumber
Publikováno v:
Cancer Research. 80:4540-4551
Expression of the transcription factor brachyury (TBXT) is normally restricted to the embryo, and its silencing is epigenetically regulated. TBXT promotes mesenchymal transition in a subset of common carcinomas, and in chordoma, a rare cancer showing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908815533b7a52e81c9f891ddc448193
https://doi.org/10.1158/0008-5472.can-20-1387
https://doi.org/10.1158/0008-5472.can-20-1387