Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Richard G James"'
Autor:
Richard A Morgan, David J Rawlings, Richard G James, Jasmine N Edelstein, Tyler F Hill, Michael D Leiken, Katherine M Molloy, Glory Adekanye, Caroline Bullock, Adam S Lazorchak, Ken-Edwin Aryee, Sean P Arlauckas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e99d267b8a3846c3a680953b2c556131
Autor:
David J Rawlings, Christopher D Thouvenel, Baidong Hou, Fahd Al Qureshah, Sara Sagadiev, Shuozhi Liu, Zhaolin Hua, Mridu Acharya, Richard G James
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/de217af1026245a0b5f8742c327f3886
Autor:
Richard G James, Kathryn C Davidson, Katherine A Bosch, Travis L Biechele, Nicholas C Robin, Russell J Taylor, Michael B Major, Nathan D Camp, Kerry Fowler, Timothy J Martins, Randall T Moon
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50457 (2012)
The Wnt/ß-catenin signaling pathway controls important cellular events during development and often contributes to disease when dysregulated. Using high throughput screening we have identified a new small molecule inhibitor of Wnt/ß-catenin signali
Externí odkaz:
https://doaj.org/article/12d177eee11747f8bf4fe88ef3e0fb58
Mast cell surfaceome characterization reveals CD98 heavy chain is critical for optimal cell function
Autor:
Albert J. Seo, Richard G. James, Nicholas J. Shubin, Nathan Camp, Irina Miralda, Adrian M. Piliponsky, Nyssa B. Samanas, Siddhartha S. Saha, Gail H. Deutsch, Gauri Bhise, Manasa Acharya, Kerri Niino
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: Mast cells are involved in many distinct pathological conditions, suggesting that they recognize and respond to various stimuli and thus require a rich repertoire of cell surface proteins. However, mast cell surface proteomes have not bee
Autor:
Virginia Muir, Sara Sagadiev, Shuozhi Liu, Ursula Holder, Andrea M. Armendariz, Emmaline Suchland, Iana Meitlis, Nathan Camp, Natalia Giltiay, Jenny M. Tam, Ethan C. Garner, Carl N. Wivagg, Donna Shows, Richard G. James, Adam Lacy-Hulbert, Mridu Acharya
Publikováno v:
Autophagy.
Macroautophagy/autophagy proteins have been linked with the development of immune-mediated diseases including lupus, but the mechanisms for this are unclear due to the complex roles of these proteins in multiple immune cell types. We have previously
Autor:
Rene Yu-Hong Cheng, Joseph de Rutte, Andee R. Ott, Lucienne Bosler, Wei-Ying Kuo, Jesse Liang, Brian E Hall, David J Rawlings, Dino Di Carlo, Richard G. James
Protein secretion drives many functionsin vivo; however, methods to link secretions with surface markers and transcriptomes have been lacking. By accumulating secretions close to secreting cells held within cavity-containing hydrogel nanovials, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccadea3904798428c85ec1de4d63a983
https://doi.org/10.1101/2022.08.25.505190
https://doi.org/10.1101/2022.08.25.505190
Autor:
Erica G. Schmitt, Mike B. Jordan, Joseph A. Church, Bradly M. Bauman, Lea M. Starita, Jeffrey R. Stinson, Andrew L. Snow, Daniella M. Schwartz, Suzanne Skoda-Smith, Iana Meitlis, Manish J. Butte, Jessica Gray, David Hagin, Christopher R. Luthers, David J. Rawlings, Richard G. James, Troy R. Torgerson, Nathan Camp, Seema S. Aceves, Eric J. Allenspach, Gina Dabbah, Michael J. Bamshad, Isabelle Q. Phan, Ingrid Lundgren, Susan Schuval, Deborah A. Nickerson, Joshua D. Milner, Megan A. Cooper
Publikováno v:
American Journal of Human Genetics
American journal of human genetics, vol 107, iss 6
American journal of human genetics, vol 107, iss 6
Summary Genetic testing has increased the number of variants identified in disease genes, but the diagnostic utility is limited by lack of understanding variant function. CARD11 encodes an adaptor protein that expresses dominant-negative and gain-of-
Autor:
Eirini Vamva, Stosh Ozog, Els Verhoeyen, Richard G. James, David J. Rawlings, Bruce E. Torbett
Publikováno v:
STAR protocols. 3(1)
Measles virus envelope pseudotyped LV (MV-LV) can achieve high B cell transduction rates (up to 50%), but suffers from low titers. To overcome current limitations, we developed an optimized MV-LV production protocol that achieved consistent B cell tr
Autor:
Alan F. Rubin, Alice H. Berger, Brian H. Shirts, Jennifer N. Dines, Richard G. James, Jonathan S. Berg, Lea M. Starita, Fuki M. Hisama, Sarah E. Brnich, Hannah Gelman, Douglas M. Fowler, Jay Shendure
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-11 (2019)
Genome Medicine
Genome Medicine
Variants of uncertain significance represent a massive challenge to medical genetics. Multiplexed functional assays, in which the functional effects of thousands of genomic variants are assessed simultaneously, are increasingly generating data that c
Autor:
Julita A. Ramirez, Mark Tsang, Masaya Baba, Winnie Kwong, Janella Kang, Laura S. Schmidt, Brian M. Iritani, Terri Iwata, Heon Park, Richard G. James, Katy Cui
Publikováno v:
J Immunol
Folliculin interacting protein 1 (Fnip1) is a cytoplasmic protein originally discovered through its interaction with the master metabolic sensor 5′ AMP-activated protein kinase (AMPK) and Folliculin, a protein mutated in individuals with Birt-Hogg-