Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Richard Göttlich"'
Publikováno v:
Molecules, Vol 29, Iss 11, p 2432 (2024)
A microwave-assisted synthesis of dialkyl and cyclic H-phosphonates via bis(2,2,2 trifluoroethyl) phosphonate (BTFEP) is described. This method enables the synthesis of various cyclic H-phosphonates and hetero-substituted dialkyl H-phosphonates by si
Externí odkaz:
https://doaj.org/article/cd32cf9a3c604702b30d158f8f64c623
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 582 (2022)
After a long limbo, RNA has gained its credibility as a druggable target, fully earning its deserved role in the next generation of pharmaceutical R&D. We have recently probed the trans-activation response (TAR) element, an RNA stem–bulge–loop do
Externí odkaz:
https://doaj.org/article/048df07c2e274fd6adcb5f4b27cfd1c7
Publikováno v:
Molecules, Vol 26, Iss 7, p 1874 (2021)
Specific RNA sequences regulate functions essential to life. The Trans-Activation Response element (TAR) is an RNA stem–bulge–loop structure involved in several steps of HIV-1 replication. In this work, we show how RNA targeting can inhibit HIV-1
Externí odkaz:
https://doaj.org/article/f3527f9303274e92be19f155f99a1b3b
Autor:
Gerold Heuger, Richard Göttlich
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1226-1234 (2015)
N-Alkyl-N-chlorosulfonamides add to alkenes under copper(I) catalysis. In reactions of styrene derivatives with terminal double bonds the addition products were obtained in excellent yield and high regioselectivity. Lower yields are obtained in addit
Externí odkaz:
https://doaj.org/article/8e8851d3f4bd44eaa02a819b544d61e5
Publikováno v:
Chemistry – A European Journal.
Publikováno v:
Journal of Visualized Experiments.
Publikováno v:
Zeitschrift für anorganische und allgemeine Chemie. 648
Publikováno v:
European Journal of Organic Chemistry. 2022
Publikováno v:
European Journal of Inorganic Chemistry. 2021:2079-2088
Autor:
Caterina Carraro, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Arik Horne, Marie Oestreich, Stefanie Warnat-Herresthal, Tim Helbing, Michele De Franco, Kristian Händler, Sach Mukherjee, Thomas Ulas, Valentina Gandin, Richard Göttlich, Anna C. Aschenbrenner, Joachim L. Schultze, Barbara Gatto
Omics-based technologies are driving major advances in precision medicine but efforts are still required to consolidate their use in drug discovery. In this work, we exemplify the use of multi-omics to support the development of 3-chloropiperidines (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07456175f6b244992b66dfa217bfce40
https://doi.org/10.1101/2022.02.21.481294
https://doi.org/10.1101/2022.02.21.481294