Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Richard G, Sherlock"'
Autor:
Kathryn M. Tiplady, Thomas J. Lopdell, Richard G. Sherlock, Thomas J.J. Johnson, Richard J. Spelman, Bevin L. Harris, Stephen R. Davis, Mathew D. Littlejohn, Dorian J. Garrick
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 12, Pp 9763-9791 (2022)
ABSTRACT: Fourier-transform mid-infrared (FT-MIR) spectroscopy is a high-throughput and inexpensive methodology used to evaluate concentrations of fat and protein in dairy cattle milk samples. The objective of this study was to compare the genetic ch
Externí odkaz:
https://doaj.org/article/87ad00ec3d594691b9978de5dc621ff2
Autor:
Edwardo G. M. Reynolds, Thomas Lopdell, Yu Wang, Kathryn M. Tiplady, Chad S. Harland, Thomas J. J. Johnson, Catherine Neeley, Katie Carnie, Richard G. Sherlock, Christine Couldrey, Stephen R. Davis, Bevin L. Harris, Richard J. Spelman, Dorian J. Garrick, Mathew D. Littlejohn
Publikováno v:
Genetics Selection Evolution, Vol 54, Iss 1, Pp 1-16 (2022)
Abstract Background Deleterious recessive conditions have been primarily studied in the context of Mendelian diseases. Recently, several deleterious recessive mutations with large effects were discovered via non-additive genome-wide association studi
Externí odkaz:
https://doaj.org/article/c6d74fe902814b03a9b570eab1034eda
Autor:
Kathryn M. Tiplady, Thomas J. Lopdell, Edwardo Reynolds, Richard G. Sherlock, Michael Keehan, Thomas JJ. Johnson, Jennie E. Pryce, Stephen R. Davis, Richard J. Spelman, Bevin L. Harris, Dorian J. Garrick, Mathew D. Littlejohn
Publikováno v:
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-24 (2021)
Abstract Background Fourier-transform mid-infrared (FT-MIR) spectroscopy provides a high-throughput and inexpensive method for predicting milk composition and other novel traits from milk samples. While there have been many genome-wide association st
Externí odkaz:
https://doaj.org/article/3741a0b431e24b8783c25e8d5cfc1f73
Autor:
Carole Charlier, B.L. Harris, Michael Keehan, Dorian J. Garrick, Kathryn Tiplady, Keren E. Dittmer, Gemma Worth, Katie Carnie, Michel Georges, Chad Harland, Thomas Lopdell, Mathew Littlejohn, Catherine Neeley, Thomas Johnson, Mark Walker, Christine Couldrey, Stephen R. Davis, Richard J. Spelman, Richard G. Sherlock, Edwardo Reynolds
Publikováno v:
Nature Genetics. 53:949-954
Mammalian species carry ~100 loss-of-function variants per individual1,2, where ~1-5 of these impact essential genes and cause embryonic lethality or severe disease when homozygous3. The functions of the remainder are more difficult to resolve, altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85da76a6dbb7ea65191fc5ed105d1d47
https://doi.org/10.1038/s41588-021-00872-5
https://doi.org/10.1038/s41588-021-00872-5
Autor:
Stephen R. Davis, Chad Harland, Edwardo Reynolds, Catherine Neeley, Mathew Littlejohn, B.L. Harris, Richard G. Sherlock, Richard J. Spelman, Yu Wang, Thomas Lopdell, Katie Carnie, Christine Couldrey, Thomas Johnson, Dorian J. Garrick, Kathryn Tiplady
Deleterious recessive conditions have primarily been studied in a Mendelian disease context. Recently, several large effect, deleterious recessive mutations were discovered via non-additive GWAS of quantitative growth and developmental traits in catt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dcdbfaddb3f4ee85cdf0f431c1e56de
https://doi.org/10.1101/2021.08.30.457863
https://doi.org/10.1101/2021.08.30.457863
Autor:
Dorian J. Garrick, Richard J. Spelman, Edwardo Reynolds, Stephen R. Davis, Mathew Littlejohn, Thomas Lopdell, B.L. Harris, Thomas Johnson, Richard G. Sherlock, M. Keehan, Jennie E. Pryce, Kathryn Tiplady
Publikováno v:
Genetics, Selection, Evolution : GSE
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-24 (2021)
Genetics Selection Evolution, Vol 53, Iss 1, Pp 1-24 (2021)
Background Fourier-transform mid-infrared (FT-MIR) spectroscopy provides a high-throughput and inexpensive method for predicting milk composition and other novel traits from milk samples. While there have been many genome-wide association studies (GW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b72bfc94d34b698b751738bcbf6925
http://europepmc.org/articles/PMC8290608
http://europepmc.org/articles/PMC8290608
Autor:
Edwardo G M, Reynolds, Catherine, Neeley, Thomas J, Lopdell, Michael, Keehan, Keren, Dittmer, Chad S, Harland, Christine, Couldrey, Thomas J J, Johnson, Kathryn, Tiplady, Gemma, Worth, Mark, Walker, Stephen R, Davis, Richard G, Sherlock, Katie, Carnie, Bevin L, Harris, Carole, Charlier, Michel, Georges, Richard J, Spelman, Dorian J, Garrick, Mathew D, Littlejohn
Publikováno v:
Nature genetics. 53(7)
Mammalian species carry ~100 loss-of-function variants per individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b98754a5d82802f41f89347a7d5cacda
https://pubmed.ncbi.nlm.nih.gov/34045765
https://pubmed.ncbi.nlm.nih.gov/34045765
Autor:
B.L. Harris, Jennie E. Pryce, Richard J. Spelman, Mathew D Littlejohn, Dorian J. Garrick, Stephen R. Davis, Kathryn Tiplady, Richard G. Sherlock
Publikováno v:
Journal of dairy science. 102(7)
The use of Fourier-transform mid-infrared (FTIR) spectroscopy is of interest to the dairy industry worldwide for predicting milk composition and other novel traits that are difficult or expensive to measure directly. Although there are many valuable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae2642f11a564c3cf7b553f451b759a
https://pubmed.ncbi.nlm.nih.gov/31030929
https://pubmed.ncbi.nlm.nih.gov/31030929
Autor:
Mathew D Littlejohn, I.L. Zhang, Richard G. Sherlock, Stephen R. Davis, Christine Couldrey, Thomas Lopdell, Richard J. Spelman, M. Keehan, Andrew D Scott, Thomas Johnson, Kathryn Tiplady
Publikováno v:
Journal of dairy science. 100(7)
X chromosome inactivation (XCI) is a process by which 1 of the 2 copies of the X chromosomes present in female mammals is inactivated. The transcriptional silencing of one X chromosome achieves dosage compensation between XX females and XY males and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a139dd1ac73931145d6c380ffbaf5d2d
https://pubmed.ncbi.nlm.nih.gov/28477999
https://pubmed.ncbi.nlm.nih.gov/28477999
Autor:
Chad Harland, M. Keehan, Christine Couldrey, Thomas Lopdell, Stephen R. Davis, Klaus Lehnert, Richard J. Spelman, Russell G. Snell, Andrew D Scott, Mathew D Littlejohn, Thomas Johnson, Tania Fink, Kathryn Tiplady, Richard G. Sherlock
Publikováno v:
Scientific Reports
The mammary gland is a prolific lipogenic organ, synthesising copious amounts of triglycerides for secretion into milk. The fat content of milk varies widely both between and within species and recent independent genome-wide association studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d335226eb22aa4deadd62dbc27add40