Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Richard G, Phelps"'
Publikováno v:
F1000Research, Vol 4 (2015)
Background: Angiotensin converting enzyme inhibitors (ACEi) reduce proteinuria and preserve kidney function in proteinuric renal diseases. Their nephroprotective effect exceeds that attributable to lowering of blood pressure alone. This study examine
Externí odkaz:
https://doaj.org/article/7acb3320a7b0416f8a10fb8911e82aed
Autor:
Daniel Wynn, David Margolin, Richard G Phelps, Glen S. Markowitz, Alasdair Coles, Mario Habek, Claudio E Rodriguez, Darren P Baker, Hans-Peter Hartung, Jonathan A. Winston, Eva Havrdova
Publikováno v:
Multiple Sclerosis (Houndmills, Basingstoke, England)
Phelps, R, Winston, J A, Wynn, D, Habek, M, Hartung, H-P, Havrdová, E K, Markowitz, G S, Margolin, D H, Rodriguez, C E, Baker, D P & Coles, A J 2019, ' Incidence, management, and outcomes of autoimmune nephropathies following alemtuzumab treatment in patients with multiple sclerosis ', Multiple Sclerosis Journal, pp. 1352458519841829 . https://doi.org/10.1177/1352458519841829
Phelps, R, Winston, J A, Wynn, D, Habek, M, Hartung, H-P, Havrdová, E K, Markowitz, G S, Margolin, D H, Rodriguez, C E, Baker, D P & Coles, A J 2019, ' Incidence, management, and outcomes of autoimmune nephropathies following alemtuzumab treatment in patients with multiple sclerosis ', Multiple Sclerosis Journal, pp. 1352458519841829 . https://doi.org/10.1177/1352458519841829
Background: Autoimmune disorders including nephropathies have been reported more frequently in alemtuzumab-treated multiple sclerosis (MS) patients than in the general population. Objective: Describe instances of autoimmune nephropathy in alemtuzumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cbb60d65292860c592c902ee0dbb1c
https://pubmed.ncbi.nlm.nih.gov/31368417
https://pubmed.ncbi.nlm.nih.gov/31368417
Publikováno v:
Ochsenkuehn, M A, Borek, J A, Phelps, R & Campbell, C J 2011, ' Redox Potential Dependence of Peptide Structure Studied Using Surface Enhanced Raman Spectroscopy ', Nano Letters, vol. 11, no. 7, pp. 2684-2688 . https://doi.org/10.1021/nl200885p
We describe a novel surface enhanced Raman spectroscopy (SERS) sensing approach utilizing modified gold nanoshells and demonstrate its application to analysis of critical redox-potential dependent changes in antigen structure that are implicated in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6b4db24f90cee9a20336822bfe43dc
https://doi.org/10.1021/nl200885p
https://doi.org/10.1021/nl200885p
Autor:
Richard G Phelps, Lindsay S. Cairns, Juan Zou, Andrew J. Rees, Robert N. Barker, Sigrid Hannier, A Neil Turner
Publikováno v:
Journal of the American Society of Nephrology. 19:396-404
Autoreactive T cells in patients with Goodpasture's disease are specific for epitopes in the Goodpasture antigen (the NC1 domain of the alpha3 chain of type IV collagen) that are rapidly destroyed during antigen processing to a degree that diminishes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4240d80df085cdc6b4dd296b70e055
https://doi.org/10.1681/asn.2007050546
https://doi.org/10.1681/asn.2007050546
Publikováno v:
Journal of the American Society of Nephrology. 18:771-779
The most abundant autoreactive T cells in patients with Goodpasture's disease are specific for peptides in the autoantigen that have high affinity for the disease-associated HLA class II molecule, DR15. How can such T cells escape self-tolerance mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312e0358a1a390b45efa1a1973480ec6
https://doi.org/10.1681/asn.2006091056
https://doi.org/10.1681/asn.2006091056
Publikováno v:
Analytical Chemistry. 76:1445-1452
We describe a novel nonradioactive protein-labeling technique that permits mass spectrometric identification of fragments of labeled proteins. Proteins are labeled by modulating their content of carbon-13 and labeled fragments identified from the dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9778d937ec476091df5af5709ddaa5c9
https://doi.org/10.1021/ac035160i
https://doi.org/10.1021/ac035160i
Autor:
Ben C, Reynolds, Darryl G, Turner, Rhoanne C, McPherson, Catriona T, Prendergast, Richard G, Phelps, Neil A, Turner, Richard A, O'Connor, Stephen M, Anderton
Publikováno v:
European Journal of Immunology
Interest in manipulating the immunosuppressive powers of Foxp3-expressing T regulatory cells as an immunotherapy has been tempered by their reported ability to produce proinflammatory cytokines when manipulated in vitro, or in vivo. Understanding pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91dda3156afbe17061f52e046afa6718
https://pubmed.ncbi.nlm.nih.gov/25168419
https://pubmed.ncbi.nlm.nih.gov/25168419
Publikováno v:
Journal of Biological Chemistry. 273:11440-11447
Class II molecules are believed to influence immune responses by selectively binding antigen-derived peptides for recognition by T cells. In Goodpasture's (anti-glomerular basement membrane) disease, autoimmunity to the NC1 domain of the alpha3-chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d82bce2325aebbca29e518066bd03ce
https://doi.org/10.1074/jbc.273.19.11440
https://doi.org/10.1074/jbc.273.19.11440
Autor:
Richard G Phelps, Jeremy Hughes, David C. Kluth, Fiona Duthie, Sharleen Hill, Vipin Zamvar, Paul McGeehan, David A. Ferenbach
Publikováno v:
Nephron. Clinical practice
Background/Aims: Acute kidney injury (AKI) following cardiac surgery is a complication associated with high rates of morbidity and mortality. We compared staging systems for the diagnosis of AKI after cardiac surgery, and assessed pre-operative facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83478a4ddbb44bdeb3f7839745abb069
https://pubmed.ncbi.nlm.nih.gov/25358798
https://pubmed.ncbi.nlm.nih.gov/25358798
