Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Richard Frothingham"'
Autor:
Kristen L Jurcic Smith, Divey Saini, Svetoslav Bardarov, Michelle Larsen, Richard Frothingham, Neel R Gandhi, William R Jacobs, A Willem Sturm, Sunhee Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94953 (2014)
Bacterial drug resistance is often associated with a fitness cost. Large outbreaks of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB have been described that predominately affect persons with HIV infection. We obtained four closely
Externí odkaz:
https://doaj.org/article/f21c32cad75048df8fe5e5ff90955769
Autor:
Casey C Perley, Marc Frahm, Eva M Click, Karen M Dobos, Guido Ferrari, Jason E Stout, Richard Frothingham
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e98938 (2014)
Vaccine-induced human antibodies to surface components of Haemophilus influenzae and Streptococcus pneumonia are correlated with protection. Monoclonal antibodies to surface components of Mycobacterium tuberculosis are also protective in animal model
Externí odkaz:
https://doaj.org/article/f6a6169ce1754cdcb1e67fb481b8db0e
Autor:
Manjunatha M Venkataswamy, Tony W Ng, Shalu S Kharkwal, Leandro J Carreño, Alison J Johnson, Shajo Kunnath-Velayudhan, Zheng Liu, Robert Bittman, Peter J Jervis, Liam R Cox, Gurdyal S Besra, Xiangshu Wen, Weiming Yuan, Moriya Tsuji, Xiangming Li, David D Ho, John Chan, Sunhee Lee, Richard Frothingham, Barton F Haynes, Michael W Panas, Geoffrey O Gillard, Jaimie D Sixsmith, Birgit Korioth-Schmitz, Joern E Schmitz, Michelle H Larsen, William R Jacobs, Steven A Porcelli
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108383 (2014)
Recombinant Mycobacterium bovis bacillus Calmette-Guèrin (rBCG) has been explored as a vector for vaccines against HIV because of its ability to induce long lasting humoral and cell mediated immune responses. To maximize the potential for rBCG vacci
Externí odkaz:
https://doaj.org/article/90e45a31ded54c5cbca2c3231d0f0e54
Autor:
Pablo Bifani, Barun Mathema, Martha Campo, Soraya Moghazeh, Beth Nivin, Elena Shashkina, Jeffrey Driscoll, Sonal S. Munsiff, Richard Frothingham, Barry N. Kreiswirth
Publikováno v:
Emerging Infectious Diseases, Vol 7, Iss 5, Pp 842-848 (2001)
A distinct branch of the Mycobacterium tuberculosis W phylogenetic lineage (W14 group) has been identified and characterized by various genotyping techniques. The W14 group comprises three strain variants: W14, W23, and W26, which accounted for 26 cl
Externí odkaz:
https://doaj.org/article/c50b7723a800483d83764de386a35a00
Autor:
Richard Frothingham, Spartaco Bellomo
Publikováno v:
Emerging Infectious Diseases, Vol 11, Iss 6, Pp 985-987 (2005)
Externí odkaz:
https://doaj.org/article/1b7b3134927b4009b65aba1c1a950d2b
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69804 (2013)
Cryptococcus is an emerging global health threat that is annually responsible for over 1,000,000 infections and one third of all AIDS patient deaths. There is an ongoing outbreak of cryptococcosis in the western United States and Canada. Cryptococcos
Externí odkaz:
https://doaj.org/article/1e9fd044d124459fb099e213dfeb2781
Autor:
Richard Frothingham
Publikováno v:
Emerging Infectious Diseases, Vol 10, Iss 1, Pp 156-157 (2004)
Externí odkaz:
https://doaj.org/article/837e3bef915f41578aeb3b9c73abb32a
Autor:
Casey C. Perley, Richard Frothingham, Norman L. Letvin, Eva M. Click, Birgit Korioth-Schmitz, Sunhee Lee, Jaimie D. Sixsmith
Publikováno v:
Vaccine. 33(42):5715-5722
Background A recombinant Mycobacterium bovis BCG (rBCG) vector expressing HIV transgenes is an attractive candidate as a dual vaccine against HIV and TB. However, pre-existing immune responses to mycobacteria may influence immune responses to rBCG. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984a3c39c1c549497731d4f71c7ca8ab
Autor:
Jaimie D. Sixsmith, Sunhee Lee, Rose Asrican, Barton F. Haynes, Swati D. G. Rayasam, Amanda E. Jimenez, Linda Berney-Meyer, Kim Vermeul, Steven A. Porcelli, William R. Jacobs, David M. Tobin, Priyadharshini Pajanirassa, Leslie Magtanong, Regy Lukose, Michelle H. Larsen, So-Yon Lim, Joern E. Schmitz, Sommer J. R. Souther, Richard Frothingham, Ching Ju Chen, Bryan E. Hart, Tony W. Ng, Sarah A. Seay, Joseph W. Saelens
Publikováno v:
Clinical and Vaccine Immunology. 22:726-741
The well-established safety profile of the tuberculosis vaccine strain,Mycobacterium bovisbacille Calmette-Guérin (BCG), makes it an attractive vehicle for heterologous expression of antigens from clinically relevant pathogens. However, successful g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64466bc38d0f4bc11434cb98ca9a4319
https://doi.org/10.1128/cvi.00075-15
https://doi.org/10.1128/cvi.00075-15
Autor:
Dan Huang, Andrew A. Lackner, Peter J. Didier, Huiyong Wei, Pyone P. Aye, William R. Jacobs, Richard Frothingham, Vasan K. Sambandamurthy, Tsungda Hsu, Norman L. Letvin, Linyun Shao, Zheng W. Chen, Michelle H. Larsen, Barton F. Haynes, Bing Chen, Karolin Biermann
Publikováno v:
Vaccine. 27:4709-4717
Tuberculosis (TB) remains a global health burden for which safe vaccines are needed. BCG has limitations as a TB vaccine so we have focused on live attenuated Mycobacterium tuberculosis mutants as vaccine candidates. Prior to human studies, however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e051f88902a2b73c1febc6ba9188084
https://doi.org/10.1016/j.vaccine.2009.05.050
https://doi.org/10.1016/j.vaccine.2009.05.050