Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Richard F. Venn"'
Publikováno v:
Journal of Chromatography B. 817:77-80
This communication describes the invention and further development of the first 96-well solid-phase extraction system and the original purposes to which it was put. We also describe the adaption of this system for bioanalysis of pharmaceutically acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e174c1a9c46482b20497800c180e5b
https://doi.org/10.1016/j.jchromb.2004.08.029
https://doi.org/10.1016/j.jchromb.2004.08.029
Autor:
A Holmberg, J Stokes, B Sellergren, Richard F. Venn, Christophe Chassaing, C. Berggren, F Lanza
Publikováno v:
Journal of Chromatography B. 804:71-81
The use of molecularly imprinted polymers (MIPs) as sorbents for the solid phase extraction (SPE) of a pharmaceutical compound in development, prior to quantitative analysis was investigated. Three MIPs were synthesised using a structural analogue as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2352ad762d1e0db250d20c7d9f2250ff
https://doi.org/10.1016/j.jchromb.2003.12.011
https://doi.org/10.1016/j.jchromb.2003.12.011
Publikováno v:
Chromatographia. 56:237-241
Molecularly imprinted polymers have been evaluated at the sample clean-up stage in the analysis of a drug lead compound. In order to circumvent quantification problems related to bleeding of the template, a structurally related analogue of the latter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20ef9289be5f0cda9ed48fc7f5877c55
https://doi.org/10.1007/bf02493219
https://doi.org/10.1007/bf02493219
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 22:773-780
A selective method for the determination of sulphobutylether-beta-cyclodextrin (SBECD) in human plasma has been developed and validated over the range 4-200 microg ml(-1). SBECD is extracted from plasma using end-capped cyclohexyl solid phase extract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e9cb500fec71a55f425c1c0d3d18e9
https://doi.org/10.1016/s0731-7085(99)00283-6
https://doi.org/10.1016/s0731-7085(99)00283-6
Autor:
Richard F. Venn, Christophe Chassaing, Paul V Macrae, Patricia Wright, Kenneth Saunders, J. Luckwell
Publikováno v:
Chromatographia. 53:122-130
Turbulent flow chromatography coupled to tandem mass spectrometry (TFC-MS-MS) has recently emerged as a potentially fast, sensitive and specific technique for the direct analysis of pharmaceutical compounds from crude plasma. TFC-MS-MS removes the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30e43b64a7d0f847104dffb983205ea5
https://doi.org/10.1007/bf02491558
https://doi.org/10.1007/bf02491558
Publikováno v:
Chromatographia. 52:S83-S86
HPLC methods with fluorescence detection have been developed for the determination of sulphobutylether-β-cyclodextrin sodium (SBECD), a novel excipient for use with drugs of limited aqueous solubility, in human plasma and urine. SBECD contains no ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fe65dc42fa8390d4bccba511e6f593
https://doi.org/10.1007/bf02493131
https://doi.org/10.1007/bf02493131
Publikováno v:
Chromatographia. 52:S87-S91
A sensitive and specific method for the analysis of CP-122,288 in plasma has been developed and validated using column-switching HPLC with fluorescence detection. Solid-phase extraction (SPE) cartridges (Chem-Elut) are used to extract analyte and int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad5c52cb1f025249e7ccf5a8567418f7
https://doi.org/10.1007/bf02493132
https://doi.org/10.1007/bf02493132
Autor:
R. J. Goody, Richard F. Venn
Publikováno v:
Chromatographia. 50:407-414
A molecularly imprinted polymer has been developed which subsequently demonstrated an ability to selectively retain darifenacin (UK-88, 525-S) from aqueous acetonitrile when used as a stationary phase in HPLC columns and as a packing in solid-phase e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a788749c937c677ed45d7b0717221903
https://doi.org/10.1007/bf02490734
https://doi.org/10.1007/bf02490734
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 16:883-892
Sampatrilat is a dual inhibitor of angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) under development for the treatment of hypertension and congestive heart failure. In order to support the early clinical development (with oral adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60722d69eba79f761dcdfb7b646a107f
https://doi.org/10.1016/s0731-7085(97)00127-1
https://doi.org/10.1016/s0731-7085(97)00127-1
