Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Richard F Loeser"'
Autor:
Amanda E Nelson, Thomas H Keefe, Todd A Schwartz, Leigh F Callahan, Richard F Loeser, Yvonne M Golightly, Liubov Arbeeva, J S Marron
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0266964 (2022)
ObjectiveTo apply biclustering, a methodology originally developed for analysis of gene expression data, to simultaneously cluster observations and clinical features to explore candidate phenotypes of knee osteoarthritis (KOA) for the first time.Meth
Externí odkaz:
https://doaj.org/article/302bf74b020e4cf09e91a1a153ad40fc
Autor:
Richard F Loeser, Amy L Olex, Margaret A McNulty, Cathy S Carlson, Michael Callahan, Cristin Ferguson, Jacquelyn S Fetrow
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54633 (2013)
Osteoarthritis (OA) is the most common form of arthritis and has multiple risk factors including joint injury. The purpose of this study was to characterize the histologic development of OA in a mouse model where OA is induced by destabilization of t
Externí odkaz:
https://doaj.org/article/b0c01397a3734e1780e17026bc1899f4
Autor:
Stephen P. Messier, Leigh F. Callahan, Elena Losina, Shannon L. Mihalko, Ali Guermazi, Edward Ip, Gary D. Miller, Jeffrey N. Katz, Richard F. Loeser, Brian G. Pietrosimone, Sandra Soto, James L. Cook, Jovita J. Newman, Paul DeVita, Kurt P. Spindler, Jos Runhaar, Cortney Armitano-Lago, Vicky Duong, Faith Selzer, Ryan Hill, Monica Love, Daniel P. Beavers, Santiago Saldana, Aaron M. Stoker, Paige E. Rice, David J. Hunter
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 1, Pp 100418- (2024)
Background: Osteoarthritis (OA), the leading cause of disability among adults, has no cure and is associated with significant comorbidities. The premise of this randomized clinical trial is that, in a population at risk, a 48-month program of dietary
Externí odkaz:
https://doaj.org/article/ab6de8b677374b74baf57eb598244337
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 4, Pp 100317- (2022)
Objective: To examine the plasma microbiome for differences between obese individuals with and without osteoarthritis (OA) and its association with serum lipopolysaccharide (LPS). Design: Blood samples from 70 participants with body mass index (BMI)
Externí odkaz:
https://doaj.org/article/3b40bdc059884fa2b496b6c242314bfd
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 1, Pp 100136- (2021)
Objective: In previous studies, we determined an association between increased serum and articular cartilage levels of CCL2 with osteoarthritis (OA) progression, cartilage damage and increased MMP13 in cartilage. Here we analyzed CCL2 downstream sign
Externí odkaz:
https://doaj.org/article/050f4c48c55c470c9812a7ddeaddc012
Autor:
M. Kyla Shea, Sarah L. Booth, Stephanie G. Harshman, Donald Smith, Cathy S. Carlson, Lindsey Harper, Alexandra R. Armstrong, Min Fang, M. Leonor Cancela, Márcio Simão, Richard F. Loeser
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 3, Pp 100078- (2020)
Summary: Objective: While a role for vitamin K in maintaining joint tissue homeostasis has been proposed based on the presence of vitamin K dependent proteins in cartilage and bone, it is not clear if low vitamin K intake is causally linked to joint
Externí odkaz:
https://doaj.org/article/d10933dfac2842a89f31ef84237a99cd
Autor:
Thomas P. Andriacchi, Timothy M. Griffin, Richard F. Loeser, Jr., Constance R. Chu, Ewa M. Roos, Gillian A. Hawker, Jennifer C. Erhart-Hledik, Arielle G. Fischer
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 1, Pp 100026- (2020)
Summary: Objective: To stimulate future research directions that seek solutions for osteoarthritis (OA) at the interface between diverse disciplines and address osteoarthritis (OA) as a serious disease with a complexity that has presented a barrier t
Externí odkaz:
https://doaj.org/article/4a73644692c74f389775fbfdd80748e6
Autor:
Earnest L. Taylor, John A. Collins, Pryia Gopalakrishnan, Susan Chubinskaya, Richard F. Loeser
Publikováno v:
Osteoarthritis and Cartilage.
Autor:
Tonia L. Vincent, Tamara Alliston, Mohit Kapoor, Richard F. Loeser, Linda Troeberg, Christopher B. Little
Publikováno v:
Clinics in Geriatric Medicine. 38:193-219
Autor:
Michaela E. Copp, Jacqueline Shine, Hannon L. Brown, Kirti R. Nimmala, Susan Chubinskaya, John A. Collins, Richard F. Loeser, Brian O. Diekman
While advanced age has long been recognized as the greatest risk factor for osteoarthritis (OA), the biological mechanisms behind this connection remain unclear. Previous work has demonstrated that chondrocytes from older cadaveric donors have elevat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::760a6ba5edca6c7e94209111ab6c6d87
https://doi.org/10.1101/2023.02.27.530205
https://doi.org/10.1101/2023.02.27.530205