Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Richard F, Loeser"'
Autor:
Stephen P. Messier, Leigh F. Callahan, Elena Losina, Shannon L. Mihalko, Ali Guermazi, Edward Ip, Gary D. Miller, Jeffrey N. Katz, Richard F. Loeser, Brian G. Pietrosimone, Sandra Soto, James L. Cook, Jovita J. Newman, Paul DeVita, Kurt P. Spindler, Jos Runhaar, Cortney Armitano-Lago, Vicky Duong, Faith Selzer, Ryan Hill, Monica Love, Daniel P. Beavers, Santiago Saldana, Aaron M. Stoker, Paige E. Rice, David J. Hunter
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 1, Pp 100418- (2024)
Background: Osteoarthritis (OA), the leading cause of disability among adults, has no cure and is associated with significant comorbidities. The premise of this randomized clinical trial is that, in a population at risk, a 48-month program of dietary
Externí odkaz:
https://doaj.org/article/ab6de8b677374b74baf57eb598244337
Autor:
Richard F. Loeser, Philip R. Coryell, Alexandra R. Armstrong, John A. Collins, Priya Gopalakrishnan, Katie A. McDermott, Qitao Ran, Cathy S. Carlson
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 5, Pp 441-446 (2022)
Objective The study objective was to determine whether overexpression of the mitochondrial antioxidant peroxidase, peroxiredoxin 3 (Prx3), reduces the severity of osteoarthritis (OA) in mice. Methods Age‐related OA (age 18 and 24 months) and OA ind
Externí odkaz:
https://doaj.org/article/7d7e64fbce464e189c6ab3ea10cc62aa
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 4, Pp 100317- (2022)
Objective: To examine the plasma microbiome for differences between obese individuals with and without osteoarthritis (OA) and its association with serum lipopolysaccharide (LPS). Design: Blood samples from 70 participants with body mass index (BMI)
Externí odkaz:
https://doaj.org/article/3b40bdc059884fa2b496b6c242314bfd
Autor:
Amanda E. Nelson, Thomas H. Keefe, Todd A. Schwartz, Leigh F. Callahan, Richard F. Loeser, Yvonne M. Golightly, Liubov Arbeeva, J. S. Marron
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
Objective To apply biclustering, a methodology originally developed for analysis of gene expression data, to simultaneously cluster observations and clinical features to explore candidate phenotypes of knee osteoarthritis (KOA) for the first time. Me
Externí odkaz:
https://doaj.org/article/32496829c60c44578261dabdffd56bb5
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 1, Pp 100136- (2021)
Objective: In previous studies, we determined an association between increased serum and articular cartilage levels of CCL2 with osteoarthritis (OA) progression, cartilage damage and increased MMP13 in cartilage. Here we analyzed CCL2 downstream sign
Externí odkaz:
https://doaj.org/article/050f4c48c55c470c9812a7ddeaddc012
Autor:
M. Kyla Shea, Sarah L. Booth, Stephanie G. Harshman, Donald Smith, Cathy S. Carlson, Lindsey Harper, Alexandra R. Armstrong, Min Fang, M. Leonor Cancela, Márcio Simão, Richard F. Loeser
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 3, Pp 100078- (2020)
Summary: Objective: While a role for vitamin K in maintaining joint tissue homeostasis has been proposed based on the presence of vitamin K dependent proteins in cartilage and bone, it is not clear if low vitamin K intake is causally linked to joint
Externí odkaz:
https://doaj.org/article/d10933dfac2842a89f31ef84237a99cd
Autor:
Thomas P. Andriacchi, Timothy M. Griffin, Richard F. Loeser, Jr., Constance R. Chu, Ewa M. Roos, Gillian A. Hawker, Jennifer C. Erhart-Hledik, Arielle G. Fischer
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 1, Pp 100026- (2020)
Summary: Objective: To stimulate future research directions that seek solutions for osteoarthritis (OA) at the interface between diverse disciplines and address osteoarthritis (OA) as a serious disease with a complexity that has presented a barrier t
Externí odkaz:
https://doaj.org/article/4a73644692c74f389775fbfdd80748e6
Autor:
Earnest L. Taylor, John A. Collins, Pryia Gopalakrishnan, Susan Chubinskaya, Richard F. Loeser
Publikováno v:
Osteoarthritis and Cartilage.
Autor:
Tonia L. Vincent, Tamara Alliston, Mohit Kapoor, Richard F. Loeser, Linda Troeberg, Christopher B. Little
Publikováno v:
Clinics in Geriatric Medicine. 38:193-219
Autor:
Gary D. Miller, Matthew J Scarlett, Felix Eckstein, Shannon L. Mihalko, Barbara J. Nicklas, Ali Guermazi, Stephen P. Messier, Richard F. Loeser, Daniel P. Beavers, David J. Hunter, Mary F. Lyles, Jovita J. Newman, Paul DeVita
Publikováno v:
Arthritis Care & Research. 74:607-616
OBJECTIVE To determine whether long-term diet (D) and exercise (E) interventions, alone or in combination (D+E), have beneficial effects for older adults with knee osteoarthritis 3.5-years after the interventions end. METHODS This is a secondary anal