Výsledky vyhledávání - "Richard Essner"

Akademický článek

Implications of tumor-positive sentinel lymph nodes in single vs multiple nodal basins in melanoma

Autor: Emiliano Reyes, Kristel Lourdault, Judi Anne Ramiscal, Stacey Stern, Richard Essner

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

BackgroundMelanoma patients’ prognosis is based on the primary tumor characteristics and the tumor status of the regional lymph nodes. The advent of lymphoscintigraphy with SLN biopsy (SLNB) has shown that melanoma can drain to multiple nodal basin

Externí odkaz: https://doaj.org/article/bd9701b05d0b41dcae03222356234ff5

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Akademický článek

Pharmacodynamic Characterization of the Efficacy Signals Due to Selective BRAF Inhibition with PLX4032 in Malignant Melanoma

Autor: William D. Tap, Ke-Wei Gong, Judy Daring, Yiou Tseng, Charles Ginther, Giovanni Pauletti, John A. Glaspy, Richard Essner, Gideon Bollag, Peter Hirth, Chao Zhang, Dennis J. Slamon

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 8, Pp 637-649 (2010)

PURPOSE: About 65% to 70% of melanomas harbor a mutation in v-raf murine sarcoma viral oncogene homolog B1 (BRAF) that causes the steady-state activation of extracellular signal-regulated kinase (ERK). We sought to investigate the efficacy of PLX4032

Externí odkaz: https://doaj.org/article/7a929f77dfd249d2aa2687daa3b539ad

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Treatment Utilization and Outcomes for Locally Advanced Rectal Cancer in Older Patients

Autor: Sean Nassoiy, Wade Christopher, Rebecca Marcus, Jennifer Keller, Jessica Weiss, Shu-Ching Chang, Leland Foshag, Richard Essner, Trevan Fischer, Melanie Goldfarb

Publikováno v: JAMA surgery. 157(11)

ImportanceThe number of older patients (80 years and older) diagnosed with locally advanced rectal cancer (LARC) is expected to increase. Although current guidelines recommend neoadjuvant chemoradiation therapy (NACRT) followed by resection, little i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dededf6cb7d66be37e4bf455ef1a92
https://pubmed.ncbi.nlm.nih.gov/36169944

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The 31-gene expression profile test informs sentinel lymph node biopsy decisions in patients with cutaneous melanoma: results of a prospective, multicenter study

Autor: Maki, Yamamoto, Brenda, Sickle-Santanello, Timothy, Beard, Richard, Essner, Brian, Martin, Christine N, Bailey, J Michael, Guenther

Publikováno v: Current Medical Research and Opinion. 39:417-423

The 31-gene expression profile test (Class 1A: low-risk; 1B/2A: intermediate-risk; 2B: high-risk) is validated to identify patients with cutaneous melanoma who can safely forego sentinel lymph node biopsy (SLNB). The objective of the current study is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2434c962b7a203e4829ea37baa6e86
https://doi.org/10.1080/03007995.2023.2165813

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Evolving management of early stage pancreatic adenocarcinoma in older patients

Autor: Sean Nassoiy, Wade Christopher, Rebecca Marcus, Jennifer Keller, Jessica Weiss, Shu-Ching Chang, Richard Essner, Leland Foshag, Trevan Fischer, Melanie Goldfarb

Publikováno v: The American Journal of Surgery. 225:212-219

Due to the aging population, the number of older patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) will continue to rise.Utilizing the NCDB from 2010 to 2016, patients with early stage, clinically node negative PDAC who were ≥70 years

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21160ab72ddc0a3fc61b543ef2e2c0ec
https://doi.org/10.1016/j.amjsurg.2022.07.026

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Predicting Regional Lymph Node Recurrence in the Modern Age of Tumor-Positive Sentinel Node Melanoma: The Role of the First Postoperative Ultrasound

Autor: Jennifer Keller, Stacey Stern, Shu-Ching Chang, Rebecca Marcus, Jessica Weiss, Sean Nassoiy, Wade Christopher, Trevan Fischer, Richard Essner

Publikováno v: Annals of surgical oncology. 29(13)

The Multicenter Selective Lymphadenectomy Trial II (MSLT-II) led to a change in the management of tumor-positive sentinel lymph nodes (SLNs) from completion node dissection (CLND) to nodal observation. This study aimed to evaluate prognostic factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb67678e8ecdba4aeaed9162bad661c
https://pubmed.ncbi.nlm.nih.gov/35989390

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