Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Richard Elledge"'
Autor:
Rong Li, Xiaowen Zhang, Bogang Wu, Yanfen Hu, Anelia Horvath, Claudine Isaacs, Yidong Chen, Leilei Qi, Huai-Chin Chiang, Haihui Pan, Alexandra Greenbaum, Elizabeth Stark, Li-Ju Wang, Bassem R. Haddad, Dionyssia Clagett, Richard Elledge
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Women with BRCA1 germline mutations have approximately an 80% lifetime chance of developing breast cancer. While the tumor suppressor function of BRCA1 in breast epithelium has been studied extensively, it is not clear whether BRCA1 deficiency in non
Externí odkaz:
https://doaj.org/article/eb98d1b26ddb49bfbcad17cbfb1f7623
Autor:
Chun-Lin Lin, Xi Tan, Meizhen Chen, Meena Kusi, Chia-Nung Hung, Chih-Wei Chou, Ya-Ting Hsu, Chiou-Miin Wang, Nameer Kirma, Chun-Liang Chen, Ching-Hung Lin, Kate I. Lathrop, Richard Elledge, Virginia G. Kaklamani, Kohzoh Mitsuya, Tim H.-M. Huang
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Chromothripsis is an event of genomic instability leading to complex chromosomal alterations in cancer. Frequent long-range chromatin interactions between transcription factors (TFs) and targets may promote extensive translocation
Externí odkaz:
https://doaj.org/article/91f5a5e5bf7c4250aa876d533ff61028
Autor:
Xiaowen Zhang, Huai-Chin Chiang, Yao Wang, Chi Zhang, Sabrina Smith, Xiayan Zhao, Sreejith J. Nair, Joel Michalek, Ismail Jatoi, Meeghan Lautner, Boyce Oliver, Howard Wang, Anna Petit, Teresa Soler, Joan Brunet, Francesca Mateo, Miguel Angel Pujana, Elizabeth Poggi, Krysta Chaldekas, Claudine Isaacs, Beth N. Peshkin, Oscar Ochoa, Frederic Chedin, Constantine Theoharis, Lu-Zhe Sun, Tyler J. Curiel, Richard Elledge, Victor X. Jin, Yanfen Hu, Rong Li
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The vast majority of BRCA1-driven breast cancers derive from luminal progenitor cells but the mechanisms of this lineage specificity are unclear. Here the authors show that dangerous accumulation of DNA-RNA hybrid structures due to RNA polymerase II
Externí odkaz:
https://doaj.org/article/38cac16b041a40679c30545eb63c3763
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 2015, Iss 9, Pp 25-29 (2015)
Externí odkaz:
https://doaj.org/article/4590f8a3672448bfa134cbe59d0dd121
Autor:
Xiaowen Zhang, Huai-Chin Chiang, Yao Wang, Chi Zhang, Sabrina Smith, Xiayan Zhao, Sreejith J. Nair, Joel Michalek, Ismail Jatoi, Meeghan Lautner, Boyce Oliver, Howard Wang, Anna Petit, Teresa Soler, Joan Brunet, Francesca Mateo, Miguel Angel Pujana, Elizabeth Poggi, Krysta Chaldekas, Claudine Isaacs, Beth N. Peshkin, Oscar Ochoa, Frederic Chedin, Constantine Theoharis, Lu-Zhe Sun, Tyler J. Curiel, Richard Elledge, Victor X. Jin, Yanfen Hu, Rong Li
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 8: Article number: 15908 (2017); Published 26 June 2017; Updated 30 March 2018 The original version of this Article omitted the following from the Acknowledgements: ‘The work was also supported by a grant to Y.H. from the Canc
Externí odkaz:
https://doaj.org/article/fa3634db093c474589df2df1375d07a4
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 9 (2015)
Women carrying BRCA1 and BRCA2 mutations have significantly elevated risk of developing breast and ovarian cancers. BRCA1 -associated breast cancer likely originates from progenitors of the luminal epithelial lineage. Recent studies indicate that rad
Externí odkaz:
https://doaj.org/article/987eb7023f4f4822ac203b47b9ab9613
Autor:
Norasate, Samarnthai, Richard, Elledge, Thomas J, Prihoda, Jian, Huang, Suleiman, Massarweh, I-Tien, Yeh
Publikováno v:
The breast journal. 18(4)
Breast cancer patients do not commonly receive anti-estrogens prior to surgical excision. We reviewed a cohort of patients who received preoperative anti-estrogen therapy after baseline biopsy and then had a repeat biopsy after several weeks on treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d49bd5d6cccc718b4d1218d9a0e6c17
https://pubmed.ncbi.nlm.nih.gov/22616615
https://pubmed.ncbi.nlm.nih.gov/22616615