Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Richard Eckner"'
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 1, Pp 186-194 (2010)
Rubinstein–Taybi syndrome (RSTS) is a complex autosomal-dominant disease characterized by mental and growth retardation and skeletal abnormalities. A majority of the individuals diagnosed with RSTS carry heterozygous mutation in the gene CREBBP, bu
Externí odkaz:
https://doaj.org/article/e83f11f72e0048fe9e82ed2b720cd694
Autor:
Hitomi Hasegawa, Kenichi Ishibashi, Shoichi Kubota, Chihiro Yamaguchi, Ryuzaburo Yuki, Haruna Nakajo, Richard Eckner, Noritaka Yamaguchi, Kazunari K Yokoyama, Naoto Yamaguchi
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116048 (2014)
Activating transcription factor 2 (ATF2) and its homolog ATF7 are phosphorylated at Thr-69/Thr-71 and at Thr-51/Thr-53, respectively, by stress-activated MAPKs regulating their transcriptional functions in G1 and S phases. However, little is known ab
Externí odkaz:
https://doaj.org/article/3a30bdb1996440998e92adc2b0256b75
Autor:
Chia-Chen Ku, Kohsuke Kato, Kan-Hung Lee, Wen-Hsin Lin, Yan-Liang Lee, Ying-Chu Lin, Shigeo Saito, Shih-Chieh Tsai, Chang-Shen Lin, Yukio Nakamura, Richard Eckner, Kyosuke Nagata, Michiya Noguchi, Jia-Bin Pan, Deng-Chyang Wu, Hiroyuki Miyoshi, Che-Jung Kuo, Kenly Wuputra, Kazunari K. Yokoyama
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
The Jun dimerization protein 2 (Jdp2) is expressed predominantly in granule cell progenitors (GCPs) in the cerebellum, as was shown in Jdp2-promoter-Cre transgenic mice. Cerebellum of Jdp2-knockout (KO) mice contains lower number of Atoh-1 positive G
Autor:
Che-Jung Kuo, Wen-Hsin Lin, Yukio Nakamura, Richard Eckner, Deng-Chyang Wu, Hiroyuki Miyoshi, Chang-Shen Lin, Shih-Chieh Tsai, Kan-Hung Lee, Ying-Chu Lin, Michiya Noguchi, Chia-Chen Ku, Kohsuke Kato, Kyosuke Nagata, Jia-Bin Pan, Kazunari K. Yokoyama, Yan-Liang Lee, Kenly Wuputra, Shigeo Saito
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
The Jun dimerization protein 2 (Jdp2) is expressed predominantly in granule cell progenitors (GCPs) in the cerebellum, as was shown in Jdp2-promoter-Cre transgenic mice. Cerebellum of Jdp2-knockout (KO) mice contains lower number of Atoh-1 positive G
Autor:
Ying-Chu Lin, Chang-Shen Lin, Kazunari K. Yokoyama, Shigeo Saito, Yukio Nakamura, Richard Eckner, Kung-Kai Kuo, Kenly Wuputra
Publikováno v:
Cellular and Molecular Life Sciences
The ability to control the transition from an undifferentiated stem cell to a specific cell fate is one of the key techniques that are required for the application of interventional technologies to regenerative medicine and the treatment of tumors an
Autor:
Ying-Chu Lin, Shyh-Shin Chiou, Chee-Yin Chai, Shin-Wei Wang, Kazunari K. Yokoyama, Cheng-Lung Steve Lin, Yu-Mei Liao, Cheng-Yi Lee, Kenly Wuputra, Kung-Kai Kuo, Shigeo Saito, Chia-Chen Ku, Deng-Chyang Wu, Hiroyuki Miyoshi, Naoto Yamaguchi, Ya-Han Yang, Chang-Sheng Lin, Chun-Chieh Wu, Sophie Wang, Hitomi Hasegawa, Li-Pin Kao, Yukio Nakamura, Richard Eckner
Publikováno v:
Cancers
Cancers, Vol 5, Iss 3, Pp 959-984 (2013)
Cancers; Volume 5; Issue 3; Pages: 959-984
Cancers, Vol 5, Iss 3, Pp 959-984 (2013)
Cancers; Volume 5; Issue 3; Pages: 959-984
We report here that the Jun dimerization protein 2 (JDP2) plays a critical role as a cofactor for the transcription factors nuclear factor-erythroid 2-related factor 2 (Nrf2) and MafK in the regulation of the antioxidants and production of reactive o
Autor:
Kung-Kai Kuo, Chen-Lung Steve Lin, Ying-Chu Lin, Kenly Wuputra, Kazunari K. Yokoyama, Chang-Shen Lin, Chia-Chen Ku, Shigeo Saito, King-Teh Lee, Ker-Kong Chen, Yen-Liang Lee, Deng-Chyang Wu, Hiroyuki Miyoshi, Chun-Chieh Wu, Yukio Nakamura, Richard Eckner, Ya-Han Yang, Sophie S.W. Wang, Ming-Ho Tsai, Chee-Yin Chai
Publikováno v:
Stem cells (Dayton, Ohio). 34(11)
The network of stemness genes and oncogenes in human patient-specific reprogrammed cancer stem cells (CSCs) remains elusive, especially in liver cancer. HepG2-derived induced pluripotent stem cell-like cells (HepG2-iPS-like cells) were generated by i
Autor:
Haruna Nakajo, Noritaka Yamaguchi, Chihiro Yamaguchi, Ryuzaburo Yuki, Naoto Yamaguchi, Kenichi Ishibashi, Richard Eckner, Shoichi Kubota, Kazunari K. Yokoyama, Hitomi Hasegawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 12, p e116048 (2014)
PLoS ONE, Vol 9, Iss 12, p e116048 (2014)
Activating transcription factor 2 (ATF2) and its homolog ATF7 are phosphorylated at Thr-69/Thr-71 and at Thr-51/Thr-53, respectively, by stress-activated MAPKs regulating their transcriptional functions in G1 and S phases. However, little is known ab
Autor:
Suk P. Oh, Nai Dong Zhou, D. Newsome, Miriam Fuchs, En Li, Richard Eckner, Lian Ee Ch'ng, Roderick T. Bronson, Tso-Pang Yao, David M. Livingston
Publikováno v:
Cell. 93:361-372
The transcriptional coactivator and integrator p300 and its closely related family member CBP mediate multiple, signal-dependent transcriptional events. We have generated mice lacking a functional p300 gene. Animals nullizygous for p300 died between
Publikováno v:
Genes & Development. 10:2478-2490
Differentiation of skeletal muscle cells and B lymphocytes is regulated by basic helix-loop-helix (bHLH) proteins. Both differentiation programs are inhibited by the adenovirus E1A oncoprotein. Analysis of E1A mutants has implicated two of its cellul