Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Richard E. Sutton"'
Autor:
Iart Luca Shytaj, Mohamed Fares, Lara Gallucci, Bojana Lucic, Mahmoud M. Tolba, Liv Zimmermann, Julia M. Adler, Na Xing, Judith Bushe, Achim D. Gruber, Ina Ambiel, Ahmed Taha Ayoub, Mirko Cortese, Christopher J. Neufeldt, Bettina Stolp, Mohamed Hossam Sobhy, Moustafa Fathy, Min Zhao, Vibor Laketa, Ricardo Sobhie Diaz, Richard E. Sutton, Petr Chlanda, Steeve Boulant, Ralf Bartenschlager, Megan L. Stanifer, Oliver T. Fackler, Jakob Trimpert, Andrea Savarino, Marina Lusic
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Combinations of direct-acting antivirals are needed to minimize drug resistance mutations and stably suppress replication of RNA viruses. Currently, there are limited therapeutic options against the severe acute respiratory syndrome coronavi
Externí odkaz:
https://doaj.org/article/30bf4bc23be645f7a9bdfa7dd16e08e5
Autor:
Penghua Wang, Long Yang, Gong Cheng, Guang Yang, Zhengyun Xu, Fuping You, Qiang Sun, Rongtuan Lin, Erol Fikrig, Richard E. Sutton
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1057-1070 (2013)
RNA viruses are sensed by RIG-I-like receptors (RLRs), which signal through a mitochondria-associated adaptor molecule, MAVS, resulting in systemic antiviral immune responses. Although RLR signaling is essential for limiting RNA virus replication, it
Externí odkaz:
https://doaj.org/article/2626379c031a43449abbce12bf42f8de
Autor:
Rebecca Slotkin, Tassos C Kyriakides, Anupam Kundu, Gary Stack, Richard E Sutton, Shaili Gupta
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0289713 (2023)
IntroductionThe objective of this study was to describe the correlation between the commercially available assay for anti-S1/RBD IgG and protective serum neutralizing antibodies (nAb) against SARS-CoV-2 in an adult population after SARS-CoV-2 vaccina
Externí odkaz:
https://doaj.org/article/dcdb98ec00b74ac6a7dab62c4e3afcf7
Autor:
Min Zhao, Pei-Yi Su, Danielle A Castro, Therese N Tripler, Yingxia Hu, Matthew Cook, Albert I Ko, Shelli F Farhadian, Benjamin Israelow, Charles S Dela Cruz, Yong Xiong, Richard E Sutton, Yale IMPACT Research Team
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009683 (2021)
COVID-19 is a global crisis of unimagined dimensions. Currently, Remedesivir is only fully licensed FDA therapeutic. A major target of the vaccine effort is the SARS-CoV-2 spike-hACE2 interaction, and assessment of efficacy relies on time consuming n
Externí odkaz:
https://doaj.org/article/b2383cfe0cfb49c9beaf80ad8a7fdffc
Autor:
Min Zhao, Rebecca Slotkin, Amar H Sheth, Lauren Pischel, Tassos C Kyriakides, Brinda Emu, Cynthia McNamara, Qiaosu Shi, Jaden Delgobbo, Jin Xu, Elizabeth Marhoffer, Aleagia Mercer-Falkoff, Jürgen Holleck, David Ardito, Richard E Sutton, Shaili Gupta
Publikováno v:
Clinical Infectious Diseases. 76:e391-e399
Background We studied whether comorbid conditions affect strength and duration of immune responses after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger RNA vaccination in a US-based, adult population. Methods Sera (before and
Autor:
Min Zhao, Rebecca Slotkin, Amar H. Sheth, Lauren Pischel, Tassos C. Kyriakides, Brinda Emu, Cynthia McNamara, Qiaosu Shi, Jaden Delgobbo, Jin Xu, Elizabeth Marhoffer, Aleagia Mercer-Falkoff, Jürgen Holleck, David Ardito, Richard E. Sutton, Shaili Gupta
Publikováno v:
medRxiv : the preprint server for health sciences.
BackgroundWe studied whether comorbid conditions impact strength and duration of immune responses after SARS-CoV-2 mRNA vaccination in a US-based, adult population.MethodsSera (pre-and-post-BNT162b2 vaccination) were tested serially up to 12 months a
Autor:
Min, Zhao, Rebecca, Slotkin, Amar H, Sheth, Lauren, Pischel, Tassos C, Kyriakides, Brinda, Emu, Cynthia, McNamara, Qiaosu, Shi, Jaden, Delgobbo, Jin, Xu, Elizabeth, Marhoffer, Aleagia, Mercer-Falkoff, Jürgen, Holleck, David, Ardito, Richard E, Sutton, Shaili, Gupta
Publikováno v:
medRxiv
We studied whether comorbid conditions impact strength and duration of immune responses after SARS-CoV-2 mRNA vaccination in a US-based, adult population.Sera (pre-and-post-BNT162b2 vaccination) were tested serially up to 12 months after two doses of
Rev is an essential regulatory protein of Human Immunodeficiency Virus type 1 (HIV) that is found in the nucleus of infected cells. Rev multimerizes on the Rev-response element (RRE) of HIV RNA to facilitate the export of intron-containing HIV mRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febad69662dc8097c25a6058d9c191eb
https://doi.org/10.1101/2021.09.13.460071
https://doi.org/10.1101/2021.09.13.460071
Autor:
George Ssenyange, Maya Kerfoot, Min Zhao, Shelli Farhadian, Sidi Chen, Lei Peng, Ping Ren, Charles S. Dela Cruz, Shaili Gupta, Richard E. Sutton
Publikováno v:
Cell Reports Methods. 2:100252
Efficient quantitative assays for measurement of viral replication and infectivity are indispensable for future endeavors to develop prophylactic or therapeutic antiviral drugs or vaccines against SARS-CoV-2. We developed a SARS-CoV-2 cell-cell trans
Autor:
Anne N. Harrington, Emrah Gumusgoz, Kevin Y. Yip, Anurag Sethi, Axel Visel, Elizabeth Lee, Catherine S. Novak, Mengting Gu, Richard E. Sutton, Ingrid Plajzer-Frick, Iros Barozzi, Momoe Kato, Tyler H. Garvin, Len A. Pennacchio, Quan Pham, Koon-Kiu Yan, Brandon J. Mannion, Yoko Fukuda-Yuzawa, Landon L Chan, Veena Afzal, Diane E. Dickel, Mark Gerstein, Jennifer A. Akiyama, Chengfei Yan, Joel Rozowsky
Publikováno v:
Nature methods, vol 17, iss 8
Nature methods
Nature methods
Enhancers are important non-coding elements, but they have traditionally been hard to characterize experimentally. The development of massively parallel assays allows the characterization of large numbers of enhancers for the first time. Here, we dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53516be68668786171cea79b7f4b526f
https://escholarship.org/uc/item/9q55f3n7
https://escholarship.org/uc/item/9q55f3n7