Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Richard E. Kouri"'
Publikováno v:
Genomics. 29:397-402
A novel human chromosome locus-specific repetitive sequence was identified and characterized using arbitrary PCR. The repeat monomer consensus sequence is 100 bp long, and there are a minimum of 140 to 160 copies of the repetitive sequence per haploi
Autor:
Ronald A. Lubet, Richard E. Kouri, Roger A. Curren, Donald L. Putman, Leonard M. Schechtman, J. R. McCormack
Publikováno v:
Environmental and Molecular Mutagenesis. 16:13-20
BALB/c-3T3 cells were employed to examine the genotoxic potential of a variety of known chemical carcinogens. BALB/c-3T3 cells displayed a dose-dependent transformation response to a variety of carcinogens (polycyclic hydrocarbons, methylating agents
Publikováno v:
Genomics. 37(2)
Autor:
Donald L. Putman, Richard E. Kouri, John T. McCarvill, Leonard M. Schechtman, Ronald A. Lubet
Publikováno v:
Environmental and molecular mutagenesis. 16(4)
An Aroclor-induced rat hepatic S-9 metabolic activation system was incorporated into the BALB/3T3 cell transformation assay to increase its sensitivity to a wide range of procarcinogens. S-9 was prepared from Aroclor 1254-induced (500 mg/kg) Fischer
Autor:
R. E. Gaensslen, Henry C. Lee, Richard E. Kouri, Karen M. Berka, Marcia E. Lewis, David Latorra
Publikováno v:
Journal of Forensic Sciences. 35:12942J
Restriction fragment length polymorphism analysis of human deoxyribonucleic acid (DNA) using two probes, pYNH24 and CMM101, was performed on the BIOS Timeframe™ system following the Federal Bureau of Investigation (FBI) Laboratory protocol and some
Autor:
Carol J. Henry, William F. Benedict, Thomas H. Rude, Richard E. Kouri, Ronald G. Sosnowski, Rodger Curren, Karen R. Brandt, Leonard M. Schechtman
Publikováno v:
Environmental Health Perspectives
Exposure to whole cigarette smoke from reference cigarettes results in the prompt (peak activity is 6 hrs), but fairly weak (similar to 2 fold), induction of murine pulmonary microsomal monooxygenase activity. This activity can be detected by using a
Publikováno v:
In Vitro. 10:18-25
Two methods for determining the hydrocarbon-metabolizing enzyme activity of cultured mammalian cells were compared. The method designed to measure benzo[a]an-thracene-induced aryl hydrocarbon hydroxylase activity could detect and quantify enzyme acti
Publikováno v:
International Journal of Cancer. 13:714-720
Using a genetic system in which aryl hydrocarbon hydroxylase (AHH) inducibility segregates, it was observed that inducible mice are approximately 12 times more sensitive to 3-methylcholanthrene-induced tumorigenesis than their non-inducible littermat
Autor:
V.V. Kelkar, Daniel W. Nebert, N.U. Jariwala, John D. Connor, Z.E. Mielens, Leslie Z. Benet, S. Erill, R. Calvo, Richard E. Kouri, Alice E. Till, N.J. Joshi, Robert S. Sloviter, Roy C. Levitt, Eugene G. Drust, Alan R. Boobis, R.S. Gupta, Olavi Pelkonen, R. Carlos
Publikováno v:
Pharmacology. 18:I-V
Publikováno v:
JNCI: Journal of the National Cancer Institute. 54:157-162
Four 1-theta-D-arabinofuranosylcytosine (ara-C)-and one dimethylnitrosamine-transformed Syrian hamster cell lines were established. All produced tumors when inoculated into newborn hamsters. Specific chromosome changes were found in these lines consi