Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Richard E. Faulkner"'
Autor:
Julie Hawkins, Barry Sidney Orlek, Graham J. Riley, Emma J. Collings, Richard E. Faulkner, Frederick Cassidy, Michael S. G. Clark
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1411-1414
Replacement of the ester group in methyl quinuclidine-3-car☐ylate1 with a 1,2,4-triazine ring afforded the high affinity muscarinic partial agonist6a. Analogues7a,7b and7d which incorporate the 1-azabicyclo[2.2.1]heptane ring also display high affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ea1c5a5b13daed15d24c4e60cfcbcab
https://doi.org/10.1016/s0960-894x(01)80503-5
https://doi.org/10.1016/s0960-894x(01)80503-5
Autor:
Frederick Cassidy, Richard E. Faulkner, Steven Mark Bromidge, Barry Sidney Orlek, Graham J. Riley, Michael S. G. Clark, Michael S. Hadley, Geoffrey Stemp
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1185-1190
Constraining the 1,2,5,6-tetrahydropyridine ring of arecoline 1a and the related muscarinic agonists 1b–e by replacing the N-methyl group by an ethano bridge between the nitrogen and the C5-position afforded compounds 2a–e . These compounds have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::216aad058f0c90c35f39eccebc1afa80
https://doi.org/10.1016/s0960-894x(01)80326-7
https://doi.org/10.1016/s0960-894x(01)80326-7
Autor:
Barry Sidney Orlek, Graham J. Riley, Richard E. Faulkner, Steven Mark Bromidge, Frank Brown, Michael S. G. Clark, Frederick Cassidy, Loudon Julia Mary, Steven Dabbs, Emma J. Collings
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:557-562
The combination of N-methoxy imidoyl halide and nitrile moieties with the 1,2,5,6-tetrahydropyridine ring system afforded a novel series of potent muscarinic agonists. Members of this class, exemplified by the imidoyl nitriles 2c and 3c , show favour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d45b16026111b228491b57c2df1f13e
https://doi.org/10.1016/s0960-894x(01)80154-2
https://doi.org/10.1016/s0960-894x(01)80154-2
Autor:
Frank Brown, Steven Mark Bromidge, Graham J. Riley, Emma J. Collings, Loudon Julia Mary, Barry Sidney Orlek, Richard E. Faulkner, Frederick Cassidy, Michael S. G. Clark, Steven Dabbs
Publikováno v:
ChemInform. 25
The combination of N-methoxy imidoyl halide and nitrile moieties with the 1,2,5,6-tetrahydropyridine ring system afforded a novel series of potent muscarinic agonists. Members of this class, exemplified by the imidoyl nitriles 2c and 3c , show favour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7939ce7c88bc532d4d5b011567f0492
https://doi.org/10.1002/chin.199434167
https://doi.org/10.1002/chin.199434167
Autor:
Frederick Cassidy, Michael S. Hadley, Michael S. G. Clark, Geoffrey Stemp, Barry Sidney Orlek, Steven Mark Bromidge, Richard E. Faulkner, Graham J. Riley
Publikováno v:
ChemInform. 25
Constraining the 1,2,5,6-tetrahydropyridine ring of arecoline 1a and the related muscarinic agonists 1b–e by replacing the N-methyl group by an ethano bridge between the nitrogen and the C5-position afforded compounds 2a–e . These compounds have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb60ed0de1cb6d208fac15093526914e
https://doi.org/10.1002/chin.199444158
https://doi.org/10.1002/chin.199444158
Autor:
Emma J. Collings, Graham J. Riley, Michael S. G. Clark, Frederick Cassidy, Julie Hawkins, Barry Sidney Orlek, Richard E. Faulkner
Publikováno v:
ChemInform. 25
Replacement of the ester group in methyl quinuclidine-3-car☐ylate1 with a 1,2,4-triazine ring afforded the high affinity muscarinic partial agonist6a. Analogues7a,7b and7d which incorporate the 1-azabicyclo[2.2.1]heptane ring also display high affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85bf1a3b53aa932edb1fef13571425ba
https://doi.org/10.1002/chin.199447183
https://doi.org/10.1002/chin.199447183