Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Richard E Jacob"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65874 (2013)
Changes in the shape of the lung during breathing determine the movement of airways and alveoli, and thus impact airflow dynamics. Modeling airflow dynamics in health and disease is a key goal for predictive multiscale models of respiration. Past eff
Externí odkaz:
https://doaj.org/article/65566948db504ac18596788b693374f0
Autor:
Richard E Jacob, Wayne J Lamm
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27577 (2011)
Pulmonary computational fluid dynamics models require that three-dimensional images be acquired over multiple points in the dynamic breathing cycle without breath holds or changes in ventilatory mechanics. With small animals, these requirements can r
Externí odkaz:
https://doaj.org/article/8a48edefe4f242b3ab00f2e1edb88634
Autor:
Richard E Jacob, James P Carson, Kathy M Gideon, Brett G Amidan, Cathie L Smith, K Monica Lee
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6670 (2009)
In this work, we compare two methods for evaluating and quantifying pulmonary airspace enlargement in a mouse model of chronic cigarette smoke exposure. Standard stereological sample preparation, sectioning, and imaging of mouse lung tissues were per
Externí odkaz:
https://doaj.org/article/5faaaf4d72d94f7abcce1f2aa61651a0
Publikováno v:
Ultrasonics. 127:106854
Recent years have seen a substantial increase in the application of machine learning (ML) for automated analysis of nondestructive examination (NDE) data. One of the applications of interest is the use of ML for the analysis of data from in-service i
Autor:
Mital A. Zalavadia, Nikhil Deshmukh, Richard S. Wittman, Jonathan D. McCall, Erin A. Miller, Pavlo Ivanusa, Dustin M. Kasparek, Timothy A. White, Stanley L. Owsley, Kurt L. Silvers, Luke W. Campbell, Elvin Munoz, Andrew J. Gilbert, Richard E. Jacob
Publikováno v:
Anomaly Detection and Imaging with X-Rays (ADIX) VI.
Gratings-based phase contrast x-ray imaging offers enhanced material information in an x-ray imaging measurement, a key consideration for improving performance in explosives detection. Application of phase contrast imaging to explosives detection req
Autor:
Erin A. Miller, Nikhil Deshmukh, Richard S. Wittman, Dustin M. Kasparek, Luke W. Campbell, Andrew J. Gilbert, Mital A. Zalavadia, Richard E. Jacob
Publikováno v:
Anomaly Detection and Imaging with X-Rays (ADIX) VI.
Gratings-based phase contrast X-ray imaging provides additional materials signatures in textured media based on the deflection of the X-ray beam. Using this technique with a hard (~160 kVp) X-ray spectrum has shown potential for improved materials di
Autor:
Nikhil Deshmukh, Erin A. Miller, Luke W. Campbell, Richard S. Wittman, Richard E. Jacob, Andrew J. Gilbert
Publikováno v:
Anomaly Detection and Imaging with X-Rays (ADIX) IV.
Gratings-based x-ray imaging can provide additional materials signatures, including refraction which is proportional to variations in electron density, and scatter which is sensitive to sub-resolution texture. Phase contrast measurements have been co
Autor:
S.C. Taft, Richard A. Corley, Timothy M. Straub, Senthil Kabilan, Sarah Suffield, M. Moe, Stephanie A. Hines, Andrew P. Kuprat, K.P. Recknagle, J.H. Saunders, James P. Carson, Daniel R. Einstein, Justin G. Teeguarden, Sean M. Colby, Richard E. Jacob
Publikováno v:
Journal of Aerosol Science. 99:64-77
Three-dimensional computational fluid dynamics and Lagrangian particle deposition models were developed to compare the deposition of aerosolized Bacillus anthracis spores in the respiratory airways of a human with that of the rabbit, a species common
Autor:
Jinxiang Xi, Richard A. Corley, JongWon Kim, Senthil Kabilan, Xiuhua April Si, Yu Zhang, Richard E. Jacob
Publikováno v:
The Anatomical Record. 299:853-868
The rabbit is commonly used as a laboratory animal for inhalation toxicology tests and detail knowledge of the rabbit airway morphometry is needed for outcome analysis or theoretical modeling. The objective of this study is to quantify the morphometr