Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Richard E Frye"'
Autor:
Sophie Charrasse, Victor Racine, Charlotte Saint-Omer, Titouan Poquillon, Loïc Lionnard, Marine Ledru, Christophe Gonindard, Sandrine Delaunois, Karima Kissa, Richard E Frye, Manuela Pastore, Christelle Reynes, Mathilde Frechet, Hanane Chajra, Abdel Aouacheria
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0301372 (2024)
The importance of mitochondria in tissue homeostasis, stress responses and human diseases, combined to their ability to transition between various structural and functional states, makes them excellent organelles for monitoring cell health. There is
Externí odkaz:
https://doaj.org/article/efe87f5e2b374a2d96f8519f9e6efa71
Autor:
Shannon Rose, Richard E Frye, John Slattery, Rebecca Wynne, Marie Tippett, Oleksandra Pavliv, Stepan Melnyk, S Jill James
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85436 (2014)
There is increasing recognition that mitochondrial dysfunction is associated with the autism spectrum disorders. However, little attention has been given to the etiology of mitochondrial dysfunction or how mitochondrial abnormalities might interact w
Externí odkaz:
https://doaj.org/article/265b65bc38d140dfbced1f60cdeaf3c3
Publikováno v:
Frontiers in Systems Neuroscience, Vol 4 (2010)
Functional neuroimaging studies suggest that neural networks that subserve reading are organized differently in dyslexic readers (DRs) and typical readers (TRs), yet the hierarchical structure of these networks has not been well studied. We used Gran
Externí odkaz:
https://doaj.org/article/9b6d68df3a934948821da7027dbb6617
Autor:
Richard E Frye
Publikováno v:
Frontiers in Neuroscience, Vol 4 (2010)
Tetrahydrobiopterin (BH4) is a naturally occurring cofactor essential for critical metabolic pathways. Studies suggest that BH4 supplementation may ameliorate autism symptoms; the biological mechanism for such an effect is unknown. To help understand
Externí odkaz:
https://doaj.org/article/4e4725ddf40f4c15adeb654d683ea022
Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
Autor:
Richard E. Frye, Loïc Lionnard, Indrapal Singh, Mohammad A. Karim, Hanane Chajra, Mathilde Frechet, Karima Kissa, Victor Racine, Amrit Ammanamanchi, Patrick John McCarty, Leanna Delhey, Marie Tippett, Shannon Rose, Abdel Aouacheria
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated respiration rates and morphological alterations. We examined electron transport chain (ETC
Externí odkaz:
https://doaj.org/article/16d1cc2755014f93b135086f758acd28
Autor:
Andrew W. Zimmerman, Kanwaljit Singh, Susan L. Connors, Hua Liu, Anita A. Panjwani, Li-Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye, Jed W. Fahey
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-22 (2021)
Abstract Background Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic pathways. Previous clinical trials of oral SF demonstrate
Externí odkaz:
https://doaj.org/article/cfdd1aa8a2284064ac4e1899d7e775ee
Autor:
Kanwaljit Singh, Indrapal N. Singh, Eileen Diggins, Susan L. Connors, Mohammad A. Karim, David Lee, Andrew W. Zimmerman, Richard E. Frye
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 5, Pp 683-694 (2020)
Abstract Background Developmental regression (DR) occurs in about one‐third of children with Autism Spectrum Disorder (ASD) yet it is poorly understood. Current evidence suggests that mitochondrial function in not normal in many children with ASD.
Externí odkaz:
https://doaj.org/article/fe5365ba68db4c09ad79eefadc691097
Autor:
Elizabeth Berry-Kravis, Robyn A. Filipink, Richard E. Frye, Sailaja Golla, Stephanie M. Morris, Howard Andrews, Tse-Hwei Choo, Walter E. Kaufmann, The FORWARD Consortium, Milen Velinov, Amy L. Talboy, Stephanie L. Sherman, Marcy Schuster, Nicole Tartaglia, Dejan B. Budimirovic, Deborah Barbouth, Amy Lightbody, Allan Reiss, Carol M. Delahunty, Randi J. Hagerman, David Hessl, Craig A. Erickson, Gary Feldman, Jonathan D. Picker, Ave M. Lachiewicz, Holly K. Harris, Amy Esler, Patricia A. Evans, Mary Ann Morris, Barbara A. Haas-Givler, Andrea L. Gropman, Ryan S. Uy, Reymundo Lozano, Carrie Buchanan, Jean A. Frazier
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Fragile X syndrome (FXS), the most common inherited cause of intellectual disability, learning disability, and autism spectrum disorder, is associated with an increased prevalence of certain medical conditions including seizures. The goal of this stu
Externí odkaz:
https://doaj.org/article/2144dddb74154f51a1bf96b7016b2719
Autor:
Danielle Brister, Brianna A. Werner, Geoffrey Gideon, Patrick J. McCarty, Alison Lane, Brian T. Burrows, Sallie McLees, P. David Adelson, Jorge I. Arango, William Marsh, Angelea Flores, Matthew T. Pankratz, Ngoc Han Ly, Madison Flood, Danni Brown, David Carpentieri, Yan Jin, Haiwei Gu, Richard E. Frye
Publikováno v:
Metabolites, Vol 12, Iss 5, p 371 (2022)
Neurodevelopmental disorders are associated with metabolic pathway imbalances; however, most metabolic measurements are made peripherally, leaving central metabolic disturbances under-investigated. Cerebrospinal fluid obtained intraoperatively from c
Externí odkaz:
https://doaj.org/article/b9cf687b838846559d502faa354c9694
Publikováno v:
Autism Research. 15:2038-2055
Previous work identified three subgroups of children with ASD based upon co-occurring conditions (COCs) diagnosed during the first 5 years of life. This work examines prenatal risk factors, given by maternal medical claims, for each of the three subg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e7443e7ddf31abdaa9189008618388
https://doi.org/10.1002/aur.2809
https://doi.org/10.1002/aur.2809