Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Richard DeTeresa"'
Autor:
Margaret Mallory, Christine McGiffert, M. Alford, Isaac Veinbergs, Richard DeTeresa, Emily Van Uden, Robert A. Orlando, Eliezer Masliah
Publikováno v:
Experimental Neurology. 170:15-26
Apolipoprotein E (apoE) is known to bind to at least five receptors, including the low-density lipoprotein (LDL) receptor-related protein (LRP), very low density LDL receptor (VLDL-R), LDL-R, apoE receptor 2 (apoER2), and megalin/gp330. In this conte
Publikováno v:
AIDS. 14:69-74
Objective To analyze changes in frequency of systemic AIDS pathology over time and its relationship to central nervous system pathology. Design and methods A total of 390 AIDS autopsy cases obtained at University of California at San Diego Medical Ce
Publikováno v:
Gerontology. 43:109-118
Reactive glial cells are consistently found in the brain tissue of Alzheimer's disease (AD) patients. Both clustered and scattered glial cells occur in AD brain. A number of clustered microglial cells, but not astrocytes, had a positive correlation w
Autor:
Robert Katzman, Mary Sundsmo, Larry H. Yamaoka, Ronald G. Thomas, H.A.Rohan de Silva, Margaret A. Pericak-Vance, J. B. Rimmler, Tsunao Saitoh, B.L. Rosi, Akihiko Iwai, Leon J. Thal, Xiaohua Chen, Ethan Gregory, Eliezer Masliah, Lawrence A. Hansen, C. Richard Hofstetter, Yu Xia, Richard DeTeresa, Allen D. Roses
Publikováno v:
Annals of Neurology. 40:207-215
The non-Abeta component of Alzheimer's disease amyloid (NAC) is copurified with amyloid from the brain tissue of Alzheimer's disease victims and is immunohistochemically localized to amyloid fibrils. NAC is a hydrophobic peptide fragment from the NAC
Autor:
Margaret Mallory, Tsunao Saitoh, D. Iimoto, Eliezer Masliah, Richard DeTeresa, Mary Sundsmo, A. Sobel, N. Mori, Lee-Way Jin
Publikováno v:
Neurobiology of Aging. 17:331-341
Stathmin (p19), a 19-kDa cytosolic phosphoprotein, plays a key role in converting extracellular signals into intracellular biochemical changes. Antibodies and cDNA specific for stathmin were used to study its levels and localization in normal and Alz
Autor:
Richard DeTeresa, Mary Sundsmo, Eliezer Masliah, Tsunao Saitoh, Margaret Mallory, David P. Salmon, Akihiko Iwai
Publikováno v:
Brain Research. 720:230-234
NACP, the precursor of non-A beta component of Alzheimer's disease (AD) amyloid (NAC), is a synaptic protein that could potentially be involved in AD. We studied, by dot-blot, NACP levels in the frontal cortex of AD cases staged according to severity
Publikováno v:
Journal of Neuro-AIDS. 1:161-173
Publikováno v:
Brain Research. 617:258-266
About one quarter of Alzheimer's disease patients have been found to have concomitant subcortical and neocortical Lewy bodies (LBs). We compared the aberrant neuronal sprouting and the extent of neuritic and synaptic damage in these Lewy body variant
Autor:
Margaret Mallory, John C. Morris, Eliezer Masliah, Richard DeTeresa, Daniel W. McKeel, M. Alford, L. A. Hansen
Publikováno v:
Neurology. 56:127-129
The expression levels of three synaptic proteins (synaptophysin, synaptotagmin, and growth-associated protein 43 [GAP43]) in AD cases clinically classified by Clinical Dementia Rating (CDR) score were analyzed. Compared with control subjects (CDR = 0
Autor:
Margaret Mallory, Robert D. Terry, Richard DeTeresa, Bridget Carragher, S.J. Young, L. A. Hansen, Eliezer Masliah, Mark H. Ellisman
Publikováno v:
Scopus-Elsevier
Recent studies have shown that the Alzheimer disease (AD) neocortex is characterized by a loss of large neurons, the presence of dilated terminal axons, widespread loss of synapses, and a disruption of the dendritic cytoskeleton which is manifested a