Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Richard De Borja"'
Autor:
Nicholas Light, Mehdi Layeghifard, Ayush Attery, Vallijah Subasri, Matthew Zatzman, Nathaniel D. Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M. Abegglen, Daniel Albertson, Jonathan L. Finlay, Jordan R. Hansford, Sam Behjati, Anita Villani, Moritz Gerstung, Ludmil B. Alexandrov, Gino R. Somers, Joshua D. Schiffman, Varda Rotter, David Malkin, Adam Shlien
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Li-Fraumeni syndrome (LFS) is associated with pathogenic germline TP53 variants and predisposes patients to cancer; understanding the evolution and drivers of LFS-related tumours remains crucial. Here, the authors analyse 22 LFS tumours using whole-g
Externí odkaz:
https://doaj.org/article/6313943fa94246f49c0f01dd1873ed40
Autor:
Sandra Isabel, Mariana Abdulnoor, Karel Boissinot, Marc R. Isabel, Richard de Borja, Philip C. Zuzarte, Calvin P. Sjaarda, Kevin R. Barker, Prameet M. Sheth, Larissa M. Matukas, Jonathan B. Gubbay, Alisson J. McGeer, Samira Mubareka, Jared T. Simpson, Ramzi Fattouh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) was met with rapid development of robust molecular-based detection assays. Many SARS-CoV-2 molecular tests target multiple genetic regions of the virus to maximize d
Externí odkaz:
https://doaj.org/article/a6597e6f3e164ef8a2191d94f801c382
Impact of neoadjuvant chemotherapy on somatic mutation status in high-grade serous ovarian carcinoma
Autor:
Zibi Marchocki, Alicia Tone, Carl Virtanen, Richard de Borja, Blaise Clarke, Theodore Brown, Taymaa May
Publikováno v:
Journal of Ovarian Research, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Background Patients treated with neoadjuvant chemotherapy (NACT) for advanced high-grade serous ovarian carcinoma (HGSC) have a higher rate and shorter time to platinum-resistant recurrence compared to patients treated with primary cytoreduc
Externí odkaz:
https://doaj.org/article/4d6299f09403467893e382b9901bf564
Autor:
L. Jonathan Dursi, Zoltan Bozoky, Richard de Borja, Haoyuan Li, David Bujold, Adam Lipski, Shaikh Farhan Rashid, Amanjeev Sethi, Neelam Memon, Dashaylan Naidoo, Felipe Coral-Sasso, Matthew Wong, P-O Quirion, Zhibin Lu, Samarth Agarwal, Yuriy Pavlov, Andrew Ponomarev, Mia Husic, Krista Pace, Samantha Palmer, Stephanie A. Grover, Sevan Hakgor, Lillian L. Siu, David Malkin, Carl Virtanen, Trevor J. Pugh, Pierre-Étienne Jacques, Yann Joly, Steven J.M. Jones, Guillaume Bourque, Michael Brudno
Publikováno v:
Cell Genomics, Vol 1, Iss 2, Pp 100033- (2021)
We present the Canadian Distributed Infrastructure for Genomics (CanDIG) platform, which enables federated querying and analysis of human genomics and linked biomedical data. CanDIG leverages the standards and frameworks of the Global Alliance for Ge
Externí odkaz:
https://doaj.org/article/cb228eeaf5b24ef2bdf9cdff5b01b44c
Autor:
Jennifer L. Guthrie, Sarah Teatero, Sandra Zittermann, Yao Chen, Ashleigh Sullivan, Heather Rilkoff, Esha Joshi, Karthikeyan Sivaraman, Richard de Borja, Yogi Sundaravadanam, Michael Laszloffy, Lawrence Heisler, Vanessa G. Allen, Jared T. Simpson, Nahuel Fittipaldi
Publikováno v:
Journal of Clinical Virology Plus, Vol 1, Iss 1, Pp 100010- (2021)
Background: Travel-related dissemination of SARS-CoV-2 continues to contribute to the global pandemic. A novel SARS-CoV-2 lineage (B.1.177) reportedly arose in Spain in the summer of 2020, with subsequent spread across Europe linked to travel by infe
Externí odkaz:
https://doaj.org/article/8f302c6604e341e7a2621d8675e332d6
Autor:
Christine P’ng, Jeffrey Green, Lauren C. Chong, Daryl Waggott, Stephenie D. Prokopec, Mehrdad Shamsi, Francis Nguyen, Denise Y. F. Mak, Felix Lam, Marco A. Albuquerque, Ying Wu, Esther H. Jung, Maud H. W. Starmans, Michelle A. Chan-Seng-Yue, Cindy Q. Yao, Bianca Liang, Emilie Lalonde, Syed Haider, Nicole A. Simone, Dorota Sendorek, Kenneth C. Chu, Nathalie C. Moon, Natalie S. Fox, Michal R. Grzadkowski, Nicholas J. Harding, Clement Fung, Amanda R. Murdoch, Kathleen E. Houlahan, Jianxin Wang, David R. Garcia, Richard de Borja, Ren X. Sun, Xihui Lin, Gregory M. Chen, Aileen Lu, Yu-Jia Shiah, Amin Zia, Ryan Kearns, Paul C. Boutros
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-5 (2019)
Abstract Background We introduce BPG, a framework for generating publication-quality, highly-customizable plots in the R statistical environment. Results This open-source package includes multiple methods of displaying high-dimensional datasets and f
Externí odkaz:
https://doaj.org/article/4314e3a47df049aeb55750230ad05c88
Autor:
Sandra Isabel, Mariana Abdulnoor, Karel Boissinot, Marc R. Isabel, Richard de Borja, Philip C. Zuzarte, Calvin P. Sjaarda, Kevin R. Barker, Prameet M. Sheth, Larissa M. Matukas, Jonathan B. Gubbay, Allison J. McGeer, Samira Mubareka, Jared T. Simpson, Ramzi Fattouh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/cdc16fa90b1e4f4d8b9269e8db22114d
Autor:
Karl P Hodel, Richard de Borja, Erin E Henninger, Brittany B Campbell, Nathan Ungerleider, Nicholas Light, Tong Wu, Kimberly G LeCompte, A Yasemin Goksenin, Bruce A Bunnell, Uri Tabori, Adam Shlien, Zachary F Pursell
Publikováno v:
eLife, Vol 7 (2018)
Tumors defective for DNA polymerase (Pol) ε proofreading have the highest tumor mutation burden identified. A major unanswered question is whether loss of Pol ε proofreading by itself is sufficient to drive this mutagenesis, or whether additional f
Externí odkaz:
https://doaj.org/article/b21959d54c17454baf2f9fe1bada282c
Autor:
Dylan C. Kain, Sandra Isabel, Mariana Abdulnoor, Karel Boissinot, Richard De Borja, Amanda Filkin, Bernard Lam, Jason Li, Ilinca Lungu, Liz McCreight, Allison McGeer, Tony Mazzulli, Aimee Paterson, Philip Zuzarte, Felicia Vincelli, Cassandra Bergwerff, Ramzi Fattouh, Jared T. Simpson, Jennie Johnstone
Publikováno v:
Infection Control & Hospital Epidemiology. :1-5
Objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hospital outbreaks have been common and devastating during the coronavirus disease 2019 (COVID-19) pandemic. Understanding SARS-CoV-2 transmission in these environments is critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e04fea9e26957dc1c09dea77c616e8be
https://doi.org/10.1017/ice.2023.34
https://doi.org/10.1017/ice.2023.34
Autor:
Jonathan D. Wasserman, Adam Shlien, David Malkin, Ozgur Mete, Rose Chami, Nikolaus E. Wolter, Evan J. Propst, Paolo Campisi, Vito Forte, Meryl Acker, Richard de Borja, Scott Davidson, Nathaniel D. Anderson, Fabio Fuligni, Ana Stosic
Demographics and Oncogenic Variants for Tumors evaluated by WES/RNASeq. NA-Not applicable (infiltrative tumors without defined borders)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503e17d1c3847b743e217c60bee241d5
https://doi.org/10.1158/0008-5472.22430164.v1
https://doi.org/10.1158/0008-5472.22430164.v1
